(* denotes corresponding author. † denotes equal contribution. Number of Web of Science citations > 5300; Number of Google Scholar citations > 7200)
Zhang C, Hao L, Calabrese CM, Zhou Y, Choi CHJ , Xing H, Mirkin CA. Biodegradable DNA-brush block copolymer spherical nucleic acids enable transfection agent-free intracellular gene regulation. Small , 11 , 40, 5360-5368 (2015). [Abstract & Full Text] Narayan SP*, Choi CHJ* , Hao L, Calabrese CM, Auyeung E, Zhang C, Goor OJGM, Mirkin CA. The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates. Small , 11 , 33, 4173-4182 (2015). [Abstract & Full Text] Senesi AJ, Eichelsdoerfer DJ, Brown KA, Lee B, Auyeung E, Choi CHJ , Macfarlane RJ, Mirkin CA. Oligonucleotide flexibility dictates crystal quality in DNA-programmable materials. Adv. Mater. , 26 , 42, 7235-7240 (2014). [Abstract & Full Text] Wu XA*, Choi CHJ* , Zhang C, Hao L, Mirkin CA. Intracellular fate of spherical nucleic acid nanoparticle conjugates. J. Am. Chem. Soc. , 136 , 21, 7726-7733 (2014). [Abstract & Full Text] Alhasan A, Patel PC, Choi CHJ , Mirkin CA. Exosome-encased spherical nucleic acid nanoparticle conjugates as potent microRNA regulation agents. Small , 10 , 1, 186-192 (2014). [Abstract & Full Text] Weiss GJ, Chao J, Niedhart JD, Ramanathan RK, Bassett D, Neidhart JA, Choi CHJ , Chow W, Chung V, Forman SJ, Garmey E, Hwang J, Kalinoski DL, Koczywas M, Longmate J, Melton RJ, Morgan R, Oliver J, Peterkin J, Ryan JL, Schluep T, Synold T, Twardowski P, Davis ME, Yen Y. First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies. Invest. New Drugs , 31 , 4, 986-1000 (2013). [Abstract & Full Text] Zhang C, Macfarlane RJ, Young KL, Choi CHJ , Hao L, Auyeung E, Liu G, Zhao X, Mirkin CA. A general approach to DNA-programmable atom equivalents. Nat. Mater. , 12 , 8, 741-746 (2013). (This paper was highlighted in Nat. Mater. , 12 , 8, 694-696 (2013).) [Abstract & Full Text] Choi CHJ* , Hao L*, Narayan SP, Auyeung E, Mirkin CA. Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates. Proc. Natl. Acad. Sci. USA. , 110 , 19, 7625-7630 (2013). [Abstract & Full Text] Auyeung E, Macfarlane RJ, Choi CHJ , Cutler JI, Mirkin CA. Transitioning DNA-engineered nanoparticle superlattices from solution to the solid state. Adv. Mater. , 24 , 38, 5181-5186 (2012). [Abstract & Full Text] Rahman MA, Amin ARMR, Wang X, Zuckerman JE, Choi CHJ , Zhou B, Wang D, Nannapaneni S, Koenig L, Chen Z, Chen ZG, Yen Y, Davis ME, Shin DM. Systemic delivery of siRNA-nanoparticles targeting RRM2
suppresses head and neck tumor growth. J. Control. Release , 159 , 3, 384-392 (2012). [Abstract & Full Text] Zuckerman JE*, Choi CHJ* , Han H, Davis ME. Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane. Proc. Natl. Acad. Sci. USA. , 109 , 8, 3137-3142 (2012). (This paper was highlighted in Sci. Transl. Med. , 4, 123, 123ec35 (2012).) [Abstract & Full Text] Choi CHJ , Zuckerman JE, Webster P, Davis ME. Targeting kidney mesangium by nanoparticles of defined size. Proc. Natl. Acad. Sci. USA. , 108 , 16, 6656-6661 (2011). [Abstract & Full Text] Davis ME, Zuckerman JE, Choi CHJ , Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature , 469 , 7291, 1067-1070 (2010). (This paper was highlighted in Nat. Biotechnol ., 28 , 335 (2010), Nat. Rev. Drug Discov ., 9 , 359 (2010), & Angew. Chem. Int. Ed. , 49 , 36, 6258-6259 (2010).) [Abstract & Full Text] Choi CHJ , Alabi CA, Webster P, Davis ME. Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles. Proc. Natl. Acad. Sci. USA ., 107 , 3, 1235-1240 (2010). [Abstract & Full Text] Schluep T, Hwang J, Hildebrandt I, Czernin J, Choi CHJ , Alabi CA, Mack BC, Davis ME. Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements. Proc. Natl. Acad. Sci. USA., 106 , 27, 11394-11399 (2009). [Abstract & Full Text]