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高浩醫生

高浩醫生

助理院長 (研究)

內科及藥物治療學系助理教授

中大職務
  • 醫學院助理院長 (研究)
  • 內科及藥物治療學系及生物醫學學院助理教授
  • 精神科學系名譽助理教授
  • 張金菱治療柏金遜綜合症研究中心副主任
  • 李嘉誠健康科學研究所首席研究員 

  • 蔡永業腦神經科學中心首席研究員

 

專業範疇
  • 神經科學

 

教育及資歷

BMedSc (CUHK), MBChB (CUHK), PhD (UCL)

 

 

專注研究
  • 神經退化疾病中的膠質與血管細胞異常
  • 神經迴路
  • 成像技術開發

 

更多資訊


獎項榮譽

  • 國家優秀青年科學基金(港澳)得獎學者, 2021
  • 裘槎前瞻科研大獎, 2020
  • Finalist, Eppendorf 與 Science 神經生物學獎, 2014
部分論文 (只有英文版本)
 

Researcher ID: https://publons.com/researcher/2254191/ho-ko/

 

  1. Lai HM, Tang Y, Lau ZYH, Campbell RAA, Yau CN, Chan CCY, Chan DCW, Wong HKT, Yan LYC, Wu WKK, Wong SH, Kwok KW, Wing YK, Lam HHN, Ng HK, Mrsic-Flogel TD, Mok VCT, Chan JYK, Ko H. Antibody stabilization for thermally accelerated deep immunostaining. Nature Methods. 2022 (accepted)
  2. Li Z, Chen X, Vong JSL, Zhao L, Huang J, Yan LYC, Ip B, Lai HM, Mok VCT, Ko H. Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner. Communications Biology. 2021 Jun 2;4(1):656.
  3. Zhao L, Li Z, Vong JSL, Chen X, Lai HM, Yan LYC, Huang J, Sy SKH, Tian X, Huang Y, Chan HYE, So HC, Ng WL, Tang Y, Lin WJ, Mok VCT, Ko H. Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain. Nature Communications. 2020 Sep 4;11(1):4413.
  4. Li Q*, Ko H*, Qian ZM, Yan LYC, Chan DCW, Arbuthnott GW, Ke Y, Yung WH. Refinement of learned skilled movement representation in motor cortex deep output layer. Nature Communications. 2017 Jun 9; 8:15834.
  5. Ko H. Runner-up, Eppendorf and Science Prize for Neurobiology 2014. Functional organization of synaptic connectivity in the neocortex. Science. 2014 Oct 31; 346(6209):555.
  6. Ko H, Mrsic-Flogel TD, Hofer SB. Emergence of feature-specific connectivity in cortical microcircuits in the absence of visual experience. Journal of Neuroscience. 2014 July 16:34(29):9812-9816.
  7. Ko H, Cossell L, Baragli C, Antolik J, Clopath C, Hofer SB, Mrsic-Flogel TD. The emergence of functional microcircuits in visual cortex. Nature. 2013 Apr 4;496(7443):96-100.
  8. Hofer SB*, Ko H*, Pichler B, Vogelstein J, Ros H, Zeng H, Lein E, Lesica NA, Mrsic-Flogel TD. Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortexNature Neuroscience. 2011 Jul 17;14(8):1045-52.
  9. Ko H, Hofer SB, Pichler B, Buchanan KA, Sjöström PJ, Mrsic-Flogel TD. Functional specificity of local synaptic connections in neocortical networks. Nature. 2011 May 5;473(7345):87-91.