![](/20210519132757im_/https://www.cuhk.edu.hk/med/cpy/imgs/spe.gif) |
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Biography |
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Dr. Jinyue Liao received his bachelor's degree in Basic Medicine from Fudan University in 2007. During that time, he was trained in biology, biochemistry, genetics and medicine. Afterward, he received his master's degree in Biochemistry from The Hong Kong University of Science and Technology in 2012. Thereafter, he received his Ph.D. in Biomedical Sciences from The Chinese University of Hong Kong in 2017 and had postdoctoral training at the School of Biomedical Sciences, The Chinese University of Hong Kong from 2017 to 2021. His research focused on the analysis of gene regulatory networks that define the identity, development, and function of cells with a particular focus on germ cell development, regeneration and aging. His research integrates both wet (experimental) and dry (computational) components. The tools of his work include RNA-seq for gene expression, ChIP-seq for histone modifications, ATAC-seq for chromatin accessibility, and single-cell RNA-seq and single-cell ATAC-seq for individual transcriptomes and epigenomes from single cells. After he joined the department, he is working to apply his research approaches to the study of the biology of cell-free nucleic acid and the development of liquid biopsy testing. |
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Selected publications: |
J Liao, HC Suen, S Rao, AC Luk, R Zhang, AWT Lee, THT Chan, MY Cheung, HT Chu, HC So, RM Hobbs, TL Lee (2021). The single-cell epigenetic regulatory landscape in mammalian perinatal testis development. bioRxiv doi: https://doi.org/10.1101/2021.03.17.435776 |
J Liao, HC Suen, AC Luk, AWT Lee, JKW Ng, THT Chan, MY Cheung, DYL Chan, H Qi, WY Chan, RM Hobbs, TL Lee (2020). scATAC-Seq reveals epigenetic heterogeneity associated with an EMT-like process in male germline stem cells and its regulation by G9a. bioRxiv doi: https://doi.org/10.1101/2020.10.12.336834 |
J Liao, SH Ng, AC Luk, HC Suen, Y Qian, AWT Lee, J Tu, JCL Fung, NLS Tang, B Feng, WY Chan, P Fouchet, RM Hobbs, TL Lee (2019). Revealing cellular and molecular transitions in neonatal germ cell differentiation using single cell RNA sequencing. Development. 2019 Mar 27;146(6). |
C Meng, J Liao, D Zhao, H Huang, J Qin, TL Lee, D Chen, WY Chan, Y Xia (2019). L3MBTL2 regulates chromatin remodeling during spermatogenesis. Cell Death Differ. 2019 Nov;26(11):2194-207. |
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![](/20210519132757im_/https://www.cuhk.edu.hk/med/cpy/imgs/spe.gif) |
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