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Publications and Research Output

 
  1. Abbott TEF, Fowler AJ, Pelosi P, de Abreu MG, Moller AM, Canet J, Creagh-Brown B, Mythen M, Gin T, Lalu MM, Futier E, Grocott MP, Schultz MJ, Pearse RM, Grp S-C. A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. Brit J Anaesth. 2018;120(5):1066-79.

  2. Beh ZY, Osman A, Fathil S, Karmakar MK. Ultrasound guided interscalene brachial plexus block with low dose sedation - Technique of choice for reducing shoulder dislocation. Am J Emerg Med. 2018;36(4):717-8.

  3. Buse GL, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC, Sigamani A, Sessler DI, Berwanger O, Biccard BM, Pearse R, Urrutia G, Szczeklik RW, Garutti I, Srinathan S, Malaga G, Abraham V, Chow CK, Jacka MJ, Tiboni M, Ackland G, Macneil D, Sapsford R, Leuwer M, Le Manach Y, Devereaux PJ. Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis. Can J Surg. 2018;61(3):185-94.

  4. Chan H, Zhao S, Zhang L, Ho J, Leung CCH, Wong WT, Tian Y, Liu X, Kwong TNY, Chan RCY, Yu SSB, Wang MHT, Tse G, Wong SH, Chan MTV, Wu WKK. Clostridium difficile toxin B induces autophagic cell death in colonocytes. J Cell Mol Med. 2018;22(4):2469-77.

  5. Chan MTV, Chow BK, Lo T, Ko FW, Ng SS, Gin T, Hui DS. Exhaled air dispersion during bag-mask ventilation and sputum suctioning - Implications for infection control. Sci Rep-Uk. 2018;8.

  6. Dubey AK, Samanta A, Sarkar P, Karmakar MK, Mukherjee A, Loha C, Kumar M, Sahu SG, Saxena VK, Chatterjee PK. Hydrodynamic characteristics in a pilot-scale cold flow model for chemical looping combustion. Adv Powder Technol. 2018;29(6):1499-506.

  7. Flaatten H, Skaar E, Joynt GM. Understanding cardiovascular physiology of ageing. Intens Care Med. 2018;44(6):932-5.

  8. Graham MM, Sessler DI, Parlow JL, Biccard BM, Guyatt G, Leslie K, Chan MTV, Meyhoff CS, Xavier D, Sigamani A, Kumar PA, Mrkobrada M, Cook DJ, Tandon V, Alvarez-Garcia J, Villar JC, Painter TW, Landoni G, Fleischmann E, Lamy A, Whitlock R, Le Manach Y, Aphang-Lam M, Cata JP, Gao P, Terblanche NCS, Ramana PV, Jamieson KA, Bessissow A, Mendoza GR, Ramirez S, Diemunsch PA, Yusuf S, Devereaux PJ. Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery. Ann Intern Med. 2018;168(4):237-+.

  9. Joynt GM, Wong WT, Ling L, Lee A. Medical students and professionalism - Do the hidden curriculum and current role models fail our future doctors? Med Teach. 2018;40(4):395-9.

  10. Kwong TNY, Wang XS, Nakatsu G, Chow TC, Tipoe T, Dai RZW, Tsoi KKK, Wong MCS, Tse G, Chan MTV, Chan FKL, Ng SC, Wu JCY, Wu WKK, Yu J, Sung JJY, Wong SH. Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer. Gastroenterology. 2018;155(2):383-+.

  11. Lee A, Mu JL, Chiu CH, Gin T, Underwood MJ, Joynt GM. Effect of motor subtypes of delirium in the intensive care unit on fast-track failure after cardiac surgery. J Thorac Cardiov Sur. 2018;155(1):268-+.

  12. Leung CCH, Pun J, Lock G, Slade D, Gomersall CD, Wong WT, Joynt GM. Exploring the scope of communication content of mechanically ventilated patients. J Crit Care. 2018;44:136-41.

  13. Li DZ, Zhou YX, Yu J, Yu HF, Xia YQ, Zhang L, Wu WKK, Zeng Z, Yao R, Cao Y. Evaluation of a novel prognostic score based on thrombosis and inflammation in patients with sepsis: a retrospective cohort study. Clin Chem Lab Med. 2018;56(7):1182-92.

  14. Li KHC, Bazoukis G, Liu T, Li GP, Wu WKK, Wong SH, Wong WT, Chan YS, Wong MCS, Wassilew K, Vassiliou VS, Tse G. Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) in clinical practice. J Arrythm. 2018;34(1):11-22.

  15. Li XC, Xu WQ, Kang W, Wong SH, Wang MY, Zhou Y, Fang XD, Zhang XQ, Yang HM, Wong CH, To KF, Chan SL, Chan MTV, Sung JJY, Wu WKK, Yu J. Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features. Theranostics. 2018;8(6):1740-51.

  16. Li Z, Chen C, Lin YX, Li XY, Tan HN, Chan MTV, Wu WKK, Zhan ST, Cao Q, Shen JX. A novel probe for measuring tissue bioelectrical impedance to enhance pedicle screw placement in spinal surgery. Am J Transl Res. 2018;10(7):2205-12.

  17. Li Z, Jiang C, Li XY, Wu WKK, Chen X, Zhu SB, Ye CH, Chan MTV, Qian WW. Circulating microRNA signature of steroid-induced osteonecrosis of the femoral head. Cell Proliferat. 2018;51(1).

  18. Li Z, Li XY, Jiang C, Qian WW, Tse G, Chan MTV, Wu WKK. Long non-coding RNAs in rheumatoid arthritis. Cell Proliferat. 2018;51(1).

  19. Li Z, Shen JX, Chan MTV, Wu WKK. The long non-coding RNA SPRY4-IT1: An emerging player in tumorigenesis and osteosarcoma. Cell Proliferat. 2018;51(4).

  20. Li Z, Yang B, Weng XS, Tse G, Chan MTV, Wu WKK. Emerging roles of MicroRNAs in osteonecrosis of the femoral head. Cell Proliferat. 2018;51(1).

  21. Lindroth H, Bratzke L, Purvis S, Brown R, Coburn M, Mrkobrada M, Chan MTV, Davis DHJ, Pandharipande P, Carlsson CM, Sanders RD. Systematic review of prediction models for delirium in the older adult inpatient. Bmj Open. 2018;8(4).

  22. Ling L, Chan KM. Weaning adult patients with cardiogenic shock on veno-arterial extracorporeal membrane oxygenation by pump-controlled retrograde trial off. Perfusion-Uk. 2018;33(5):339-45.

  23. Myles PS, Bellomo R, Corcoran T, Forbes A, Peyton P, Story D, Christophi C, Leslie K, McGuinness S, Parke R, Serpell J, Chan MTV, Painter T, McCluskey S, Minto G, Wallace S, Anaes ANZC, C ANZI. Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery. New Engl J Med. 2018;378(24):2263-74.

  24. Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper J, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Network ACT. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery (vol 376, pg 136, 2017). New Engl J Med. 2018;378(8):782-.

  25. Nakatsu G, Zhou HK, Wu WKK, Wong SH, Coker OO, Dai ZW, Li XC, Szeto CH, Sugimura N, Lam TYT, Yu ACS, Wang XS, Chen ZG, Wong MCS, Ng SC, Chan MTV, Chan PKS, Chan FKL, Sung JJY, Yu J. Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes. Gastroenterology. 2018;155(2):529-+.

  26. Ngan Kee WD, Lee SWY, Ng FF, Khaw KS. Prophylactic Norepinephrine Infusion for Preventing Hypotension During Spinal Anesthesia for Cesarean Delivery. Anesth Analg. 2018;126(6):1989-94.

  27. Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Airway physical examination tests for detection of difficult airway management in apparently normal adult patients. Cochrane Db Syst Rev. 2018(5).

  28. Tian Y, Liu X, Jia M, Yu H, Lichtner P, Shi Y, Meng Z, Kou S, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK, Gin T, Wu WKK, Chen Z, Chan MTV. Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain (vol 128, pg 587, 2018). Anesthesiology. 2018;128(5):1049-.

  29. Tian YY, Liu XD, Jia MZ, Yu H, Lichtner P, Shi YJ, Meng ZY, Kou SL, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK, Gin T, Wu WKK, Chen ZY, Chan MTV, Stud PPAS. Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain. Anesthesiology. 2018;128(3):587-97.

  30. Tipoe TL, Wu WKK, Chung L, Gong MQ, Dong M, Liu T, Roever L, Ho J, Wong MCS, Chan MTV, Tse G, Wu JCY, Wong SH. Plasminogen Activator Inhibitor 1 for Predicting Sepsis Severity and Mortality Outcomes: A Systematic Review and Meta-Analysis. Front Immunol. 2018;9.

  31. Tse G, Gong MQ, Wong SH, Wu WKK, Bazoukis G, Lampropoulos K, Wong WT, Xia YL, Wong MCS, Liu T, Woo J, Ne IHISI. Frailty and Clinical Outcomes in Advanced Heart Failure Patients Undergoing Left Ventricular Assist Device Implantation: A Systematic Review and Meta-analysis. J Am Med Dir Assoc. 2018;19(3):255-U02.

  32. Tse G, Wong CW, Gong MQ, Wong WT, Bazoukis G, Wong SH, Li GP, Wu WKK, Tse LA, Lampropoulos K, Xia YL, Liu T, Baranchuk A, Ne IHISI. Predictive value of inter-atrial block for new onset or recurrent atrial fibrillation: A systematic review and meta-analysis. Int J Cardiol. 2018;250:152-6.

  33. Wang SP, Zhang YX, Song QL, Fang ZW, Chen Z, Zhang YM, Zhang LL, Zhang L, Niu N, Ma SC, Wang JW, Yao YQ, Hu ZM, Zhang GS. Mitochondrial Dysfunction Causes Oxidative Stress and Tapetal Apoptosis in Chemical Hybridization Reagent-Induced Male Sterility in Wheat. Front Plant Sci. 2018;8.

  34. Wang XJ, Zhang X, Chu ESH, Chen XT, Kang W, Wu F, To KF, Wong VWS, Chan HLY, Chan MTV, Sung JJY, Wu WKK, Yu J. Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis. Faseb J. 2018;32(1):37-51.

  35. Wong WT, Phua J, Joynt GM. Worldwide end-of-life practice for patients in ICUs. Curr Opin Anesthesio. 2018;31(2):172-8.

  36. Wu WKK, Sun R, Zuo T, Tian YY, Zeng ZR, Ho J, Wu JCY, Chan FKL, Chan MTV, Yu J, Sung JJY, Wong SH, Wang MH, Ng SC. A novel susceptibility locus in MST1 and gene-gene interaction network for Crohn's disease in the Chinese population. J Cell Mol Med. 2018;22(4):2368-77.

  37. Yu X, Zheng HY, Chan MTV, Wu WKK. Immune consequences induced by photodynamic therapy in non-melanoma skin cancers: a review. Environ Sci Pollut R. 2018;25(21):20569-74.

  38. Yu X, Zheng HY, Chan MTV, Wu WKK. NOVA1 acts as an oncogene in melanoma via regulating FOXO3a expression. J Cell Mol Med. 2018;22(5):2622-30.

  39. Yu X, Zheng HY, Tse G, Chan MTV, Wu WKK. Long non-coding RNAs in melanoma. Cell Proliferat. 2018;51(4).

  40. Zhang L, Hu W, Cho CH, Chan FKL, Yu J, Fitzgerald JR, Cheung CKY, Xiao ZG, Shen J, Li LF, Li MX, Wu JCY, Ling TKW, Chan JYK, Ko H, Tse G, Ng SC, Yu S, Wang MHT, Gin T, Ashktorab H, Smoot DT, Wong SH, Chan MTV, Wu WKK. Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori. J Pathol. 2018;244(4):432-44.

  41. Zhang L, Zhang YC, Wong SH, Law PTY, Zhao S, Yu J, Chan MTV, Wu WKK. Common Deregulation of Seven Biological Processes by MicroRNAs in Gastrointestinal Cancers. Sci Rep-Uk. 2018;8.


 
  1. Bayoumy A, Gong MQ, Li KHC, Wong SH, Wu WKK, Li GP, Bazoukis G, Letsas KP, Wong WT, Xia YL, Liu T, Tse G, IHIS IHIS. Spontaneous type 1 pattern, ventricular arrhythmias and sudden cardiac death in Brugada Syndrome: an updated systematic review and meta-analysis. J Geriatr Cardiol. 2017;14(10):639-43.


  2. Chan MTV, Chu MHM, Lam CKM, Jia B, Tsang S, Wu WKK. Deep anesthesia: too much of a good thing? Can J Anesth. 2017;64(6):574-80.

  3. Chang KV, Lin CP, Lin CS, Wu WT, Karmakar MK, Ozcakar L. Sonographic tracking of trunk nerves: essential for ultrasound-guided pain management and research. J Pain Res. 2017;10:79-88.

  4. Chen JF, Wang MH, Men RT, Gu DY, Liang D, Wu WKK, Chong KC, Tam G, He ML, Zee BCY. Thymidylate synthase 4R polymorphism is a prognostic biomarker in chinese gastric cancer patients. Int J Mol Med. 2017;40:S61-S.

  5. Corcoran T, Kasza J, Short TG, O'Loughlin E, Chan MTV, Leslie K, Forbes A, Paech M, Myles P, Investigators E-I. Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX). Brit J Anaesth. 2017;118(2):190-9.

  6. Critchley LAH. Meta-analyses of Bland-Altman-style cardiac output validation studies: good, but do they provide answers to all our questions? Brit J Anaesth. 2017;118(3):296-7.

  7. Flaatten H, de Lange DW, Artigas A, Bin D, Moreno R, Christensen S, Joynt GM, Bagshaw SM, Sprung CL, Benoit D, Soares M, Guidet B. The status of intensive care medicine research and a future agenda for very old patients in the ICU. Intens Care Med. 2017;43(9):1319-28.

  8. Gin T, Ho J, Leung C, Wong S, Choi G, Chan M, Wu W. Cathelicidin Depletion Aggravates Intestinal Epithelial Injury in Murine Sepsis. Anesth Analg. 2017;124:223-.

  9. Ho AMH, Leung JYC, Mizubuti GB, Contardi LH, Chan MTV, Lo TSF, Lee AKT. Inattentional blindness in anesthesiology: A simulation study. J Clin Anesth. 2017;42:36-9.

  10. Ho J, He WJ, Chan MTV, Tse G, Liu T, Wong SH, Leung CCH, Wong WT, Tsang S, Zhang L, Chan RYP, Gin T, Leung J, Lau BWM, Wu WKK, Ngai SPC. Eosinophilia and clinical outcome of chronic obstructive pulmonary disease: a meta-analysis. Sci Rep-Uk. 2017;7.

  11. Ho J, Zhang L, Liu XD, Wong SH, Wang MHT, Lau BWM, Ngai SPC, Chan H, Choi G, Leung CCH, Wong WT, Tsang S, Gin T, Yu J, Chan MTV, Wu WKK. Pathological Role and Diagnostic Value of Endogenous Host Defense Peptides in Adult and Neonatal Sepsis: A Systematic Review. Shock. 2017;47(6):673-9.

  12. Hounsome J, Lee A, Greenhalgh J, Lewis SR, Schofield-Robinson OJ, Coldwell CH, Smith AF. A systematic review of information format and timing before scheduled adult surgery for peri-operative anxiety. Anaesthesia. 2017;72(10):1265-72.

  13. Hui CYT, Leung CCH, Gomersall CD. Performance of a Novel Non-Fit-Tested HEPA Filtering Face Mask. Infect Cont Hosp Ep. 2017;38(10):1260-1.

  14. Hui DSC, Chow B, Lo T, Gin T, Chan M. Exhaled air leakage during application of high flow nasal cannula on a human patient simulator. Eur Respir J. 2017;50.

  15. Karmakar MK, Samy W, Lee A, Li JW, Chan WC, Chen PP, Tsui BCH. Survival Analysis of Patients with Breast Cancer Undergoing a Modified Radical Mastectomy With or Without a Thoracic Paravertebral Block: a 5-Year Follow-up of a Randomized Controlled Trial. Anticancer Res. 2017;37(10):5813-20.

  16. Kee WDN, Ng FF, Khaw KS, Tang SPY, Koo AGP. Dose-Response Curves for Intrathecal Bupivacaine, Levobupivacaine, and Ropivacaine Given for Labor Analgesia in Nulliparous Women. Region Anesth Pain M. 2017;42(6):788-92.

  17. Lee A, Cheung YSL, Joynt GM, Leung CCH, Wong WT, Gomersall CD. Are high nurse workload/staffing ratios associated with decreased survival in critically ill patients? A cohort study. Ann Intensive Care. 2017;7.

  18. Lee A, Mu JL, Joynt GM, Chiu CH, Lai VKW, Gin T, Underwood MJ. Risk prediction models for delirium in the intensive care unit after cardiac surgery: a systematic review and independent external validation. Brit J Anaesth. 2017;118(3):391-9.

  19. Lee A, Mu JL, Joynt GM, Chiu CH, Lai VKW, Gin T, Underwood MJ. Predicting delirium: are we there yet? (vol 119, pg 281, 2017). Brit J Anaesth. 2017;119(6):1246-.

  20. Leung YK, Cheng NM, Chan CPY, Lee A, Wong JKT, Yan BPY, Ahuja AT, Graham CA, Rainer TH. Early Exclusion of Major Adverse Cardiac Events in Emergency Department Chest Pain Patients: A Prospective Observational Study. J Emerg Med. 2017;53(3):287-94.

  21. Li JW, Songthamwat B, Samy W, Sala-Blanch X, Karmakar MK. Ultrasound-Guided Costoclavicular Brachial Plexus Block Sonoanatomy, Technique, and Block Dynamics. Region Anesth Pain M. 2017;42(2):233-40.

  22. Li Z, Li XY, Chan MTV, Wu WKK, Tan DX, Shen JX. Melatonin antagonizes interleukin-18-mediated inhibition on neural stem cell proliferation and differentiation. J Cell Mol Med. 2017;21(9):2163-71.

  23. Li Z, Li XY, Chen C, Chan MTV, Wu WKK, Shen JX. Melatonin inhibits nucleus pulposus (NP) cell proliferation and extracellular matrix (ECM) remodeling via the melatonin membrane receptors mediated PI3K-Akt pathway. J Pineal Res. 2017;63(3).

  24. Li Z, Shen JX, Chan MTV, Wu WKK. The role of microRNAs in intrahepatic cholangiocarcinoma. J Cell Mol Med. 2017;21(1):177-84.

  25. Li Z, Shen JX, Chan MTV, Wu WKK. MicroRNA-379 suppresses osteosarcoma progression by targeting PDK1. J Cell Mol Med. 2017;21(2):315-23.

  26. Liu QM, Wang QZ, Liu HG, Wu WKK, Chan MTV. Warning criteria for intraoperative neurophysiologic monitoring. Curr Opin Anesthesio. 2017;30(5):557-62.

  27. Liu Y, Zhu ZY, Ho IHT, Shi YJ, Xie YX, Li JZ, Zhang Y, Chan MTV, Cheng CHK. Germline-specific dgcr8 knockout in zebrafish using a BACK approach. Cell Mol Life Sci. 2017;74(13):2503-11.

  28. Loo JFC, Kwok HC, Leung CCH, Wu SY, Law ILG, Cheung YK, Cheung YY, Chin ML, Kwan P, Hui M, Kong SK, Ho HP. Sample-to-answer on molecular diagnosis of bacterial infection using integrated lab-on-a-disc. Biosens Bioelectron. 2017;93:212-9.

  29. Loo JFC, Leung CCH, Kwok HC, Wu SY, Law ILG, Chin ML, Hui M, Kong SK, Ho HP. Rapid molecular diagnosis of bacterial infection using integrated lab-on-a-disc. Proc Tech. 2017;27:224-5.

  30. Luk KS, Ip C, Gong MQ, Wong SH, Wu WKK, Dong M, Li GP, Chan KP, Du YM, Liu T, Wong MCS, Hui DSC, Tse G, Ne IHISI. A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension. J Geriatr Cardiol. 2017;14(12):766-71.

  31. Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Network ACT. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. New Engl J Med. 2017;376(2):136-48.

  32. Ngan Kee WD. Norepinephrine for maintaining blood pressure during spinal anaesthesia for caesarean section: a 12-month review of individual use. Int J Obstet Anesth. 2017;30:73-4.

  33. Ngan Kee WD. The use of vasopressors during spinal anaesthesia for caesarean section. Curr Opin Anesthesio. 2017;30(3):319-25.

  34. Ngan Kee WD, Khaw KS, Tam YH, Ng FF, Lee SW. Performance of a closed-loop feedback computer-controlled infusion system for maintaining blood pressure during spinal anaesthesia for caesarean section: a randomized controlled comparison of norepinephrine versus phenylephrine. J Clin Monit Comput. 2017;31(3):617-23.

  35. Ngan Kee WD, Tam YH, Khaw KS, Ng FF, Lee SWY. Closed-Loop Feedback Computer-Controlled Phenylephrine for Maintenance of Blood Pressure During Spinal Anesthesia for Cesarean Delivery: A Randomized Trial Comparing Automated Boluses Versus Infusion. Anesth Analg. 2017;125(1):117-23.

  36. Onwochei DN, Ngan Kee WD, Fung LL, Downey K, Ye XY, Carvalho JCA. Norepinephrine Intermittent Intravenous Boluses to Prevent Hypotension During Spinal Anesthesia for Cesarean Delivery: A Sequential Allocation Dose-Finding Study. Anesth Analg. 2017;125(1):212-8.

  37. Peng YM, Li Y, Jian MY, Liu XY, Sun J, Jia B, Dong J, Zeng M, Lin N, Zhang L, Gelb AW, Chan MTV, Han RQ. Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke: Protocol for a randomized controlled (CANVAS) trial. Int J Stroke. 2017;12(9):991-7.

  38. Ren NSX, Ji M, Tokar EJ, Busch EL, Xu XJ, Lewis D, Li XC, Jin AW, Zhang YP, Wu WKK, Huang WC, Li LP, Fargo DC, Keku TO, Sandler RS, Li XL. Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development. Curr Biol. 2017;27(4):483-94.

  39. Tang MH, Loo JFC, Wang YY, Zhang XP, Kwok HC, Hui MM, Leung CCH, Kong SK, Wang GH, Ho HP. Motor-assisted chip-in-a-tube (MACT): a new 2-and 3-dimensional centrifugal microfluidic platform for biomedical applications. Lab Chip. 2017;17(3):474-83.

  40. Tong CWS, Wu WKK, Loong HHF, Cho WCS, To KKW. Drug combination approach to overcome resistance to EGFR tyrosine kinase inhibitors in lung cancer. Cancer Lett. 2017;405:100-10.

  41. Tse AHW, Ling L, Joynt GM, Lee A. Prolonged infusion of sedatives and analgesics in adult intensive care patients: A systematic review of pharmacokinetic data reporting and quality of evidence. Pharmacol Res. 2017;117:156-65.

  42. Tse G, Gong MQ, Wong WT, Georgopoulos S, Letsas KP, Vassiliou VS, Chan YS, Yan BP, Wong SH, Wu WKK, Ciobanu A, Li GP, Shenthar J, Saguner AM, Ali-Hasan-Al-Saegh S, Bhardwaj A, Sawant AC, Whittaker P, Xia YL, Yan GX, Liu T. The T-peak - T-end interval as an electrocardiographic risk marker of arrhythmic and mortality outcomes: A systematic review and meta-analysis. Heart Rhythm. 2017;14(8):1131-7.

  43. Tse G, Liu T, Li GP, Keung W, Yeo JM, Chan YWF, Yan BP, Chan YS, Wong SH, Li RA, Zhao JC, Wu WKK, Wong WT. Effects of pharmacological gap junction and sodium channel blockade on S1S2 restitution properties in Langendorff-perfused mouse hearts. Oncotarget. 2017;8(49):85341-52.

  44. Tse G, Wong CW, Gong MQ, Meng L, Letsas KP, Li GP, Whittaker P, Bhardwaj A, Sawant AC, Wu WKK, Wong SH, Shenthar J, Tse LA, Wong MCS, Baranchuk A, Yan GX, Liu T, Ne IHISI. Meta-analysis of T-wave indices for risk stratification in myocardial infarction. J Geriatr Cardiol. 2017;14(12):776-9.

  45. Wang MHT, Weng HY, Sun R, Lee J, Wu WKK, Chong KC, Zee BCY. A Zoom-Focus algorithm (ZFA) to locate the optimal testing region for rare variant association tests. Bioinformatics. 2017;33(15):2330-6.

  46. Wong CCM, Zhang L, Wu WKK, Shen J, Chan RLY, Lu L, Hu W, Li MX, Li LF, Ren SX, Li YF, Li J, Cho CH. Cathelicidin-encoding Lactococcus lactis promotes mucosal repair in murine experimental colitis. J Gastroen Hepatol. 2017;32(3):609-19.

  47. Wong SH, Kwong TNY, Chow TC, Luk AKC, Dai RZW, Nakatsu G, Lam TYT, Zhang L, Wu JCY, Chan FKL, Ng SSM, Wong MCS, Ng SC, Wu WKK, Yu J, Sung JJY. Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut. 2017;66(8):1441-8.

  48. Wong SH, Zhao LY, Zhang X, Nakatsu G, Han JQ, Xu WQ, Xiao X, Kwong TNY, Tsoi H, Wu WKK, Zeng BH, Chan FKL, Sung JJY, Wei H, Yu J. Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice. Gastroenterology. 2017;153(6):1621-+.

  49. Wong WT, Gomersall CD. Adaptive support ventilation of cardiac surgical patients: A component of a complex intervention. J Crit Care. 2017;37:251-.

  50. Wu WKK, Li XC, Wang XS, Dai RZW, Cheng ASL, Wang MHT, Kwong T, Chow TC, Yu J, Chan MTV, Wong SH. Oncogenes without a Neighboring Tumor-Suppressor Gene Are More Prone to Amplification. Mol Biol Evol. 2017;34(4):903-7.

  51. Xin Y, Li Z, Zheng HY, Chan MTV, Wu WKK. CCAT2: A novel oncogenic long non-coding RNA in human cancers. Cell Proliferat. 2017;50(3).

  52. Xin Y, Li Z, Zheng HY, Ho J, Chan MTV, Wu WKK. Neuro-oncological ventral antigen 1 (NOVA1): Implications in neurological diseases and cancers. Cell Proliferat. 2017;50(4).

  53. Yu X, Li Z, Zheng HY, Chan MTV, Wu WKK. NEAT1: A novel cancer-related long non-coding RNA. Cell Proliferat. 2017;50(2).

  54. Yu X, Li Z, Zheng HY, Ho J, Chan MTV, Wu WKK. Protective roles of melatonin in central nervous system diseases by regulation of neural stem cells. Cell Proliferat. 2017;50(2).

  55. Yu X, Zheng HY, Chan MTV, Wu WKK. MicroRNAs: new players in cataract. Am J Transl Res. 2017;9(9):3896-903.

  56. Yu X, Zheng HY, Chan MTV, Wu WKK. Modulation of chemoresponsiveness to platinum-based agents by microRNAs in cancer. Am J Cancer Res. 2017;7(9):1769-78.

  57. Yu X, Zheng HY, Chan MTV, Wu WKK. BANCR: a cancer-related long non-coding RNA. Am J Cancer Res. 2017;7(9):1779-87.

  58. Yu X, Zheng HY, Chan MTV, Wu WKK. HULC: an oncogenic long non-coding RNA in human cancer. J Cell Mol Med. 2017;21(2):410-7.

  59. Zhou Y, Huang T, Zhang J, Wong CC, Zhang B, Dong Y, Wu F, Tong JHM, Wu WKK, Cheng ASL, Yu J, Kang W, To KF. TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis. Oncogene. 2017;36(47):6518-30.

  60. Zhou YH, Huang TT, Siu HL, Wong CC, Dong YJ, Wu F, Zhang B, Wu WKK, Cheng ASL, Yu J, To KF, Kang W. IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis. Mol Cancer. 2017;16.


 

 
  1. Aun CST, McBride C, Lee A, Lau ASC, Chung RCK, Yeung CK, Lai KYC, Gin T. Short-Term Changes in Postoperative Cognitive Function in Children Aged 5 to 12 Years Undergoing General Anesthesia: A Cohort Study. Medicine. 2016;95(14)

  2. Bai AHC, Wu WKK, Xu LL, Wong SH, Go MY, Chan AWH, Harbord M, Zhang SH, Chen MH, Wu JCY, Chan MWY, Chan MTV, Chan FKL, Sung JJY, Yu J, Cheng ASL, Ng SC. Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10. J Crohns Colitis. 2016;10(6):726-34.

  3. Bandeshe H, Boots R, Dulhunty J, Dunlop R, Holley A, Jarrett P, Gomersall CD, Lipman J, Lo T, O'Donoghue S, Paratz J, Paterson D, Roberts JA, Starr T, Stephens D, Stuart J, Thomas J, Udy A, White H. Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients? The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group (vol 34, pg 95, 2016). J Crit Care. 2016;35:230-.

  4. Bandeshe H, Boots R, Dulhunty J, Dunlop R, Holley A, Jarrett P, Gomersall CD, Lipman J, Lo T, O'Donoghue S, Paratz J, Paterson D, Roberts JA, Starr T, Stephens D, Stuart J, Thomas J, Udy A, White H. Is inhaled prophylactic heparin useful for prevention and Management of Pneumonia in ventilated ICU patients?. The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. J Crit Care. 2016;34:95-102.


  5. Bandeshe H, Boots R, Dulhunty J, Dunlop R, Holley A, Jarrett P, Gomersall CD, Lipman J, Lo T, O'Donoghue S, Paratz J, Paterson D, Roberts JA, Starr T, Stephens D, Stuart J, Thomas J, Udy A, White H, Australian II. Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients? J Crit Care. 2016;35:231-9.

  6. Blanch L, Abillama FF, Amin P, Christian M, Joynt GM, Myburgh J, Nates JL, Pelosi P, Sprung C, Topeli A, Vincent JL, Yeager S, Zimmerman J, Soc CTF. Triage decisions for ICU admission: Report from the Task Force of the World Federation of Societies of Intensive and Critical Care Medicine. J Crit Care. 2016;36:301-5.

  7. Chan MTV, Peyton PJ, Myles PS, Leslie K, Buckley N, Kasza J, Paech MJ, Beattie WS, Sessler DI, Forbes A, Wallace S, Chen Y, Tian Y, Wu WKK, Coll ANZ. Chronic postsurgical pain in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II trial. Brit J Anaesth. 2016;117(6):801-11.

  8. Garner AA, Lee A, Weatherall A, Langcake M, Balogh ZJ. Physician staffed helicopter emergency medical service case identification - a before and after study in children. Scand J Trauma Resus. 2016;24.

  9. Gin T, Tian Y, Liu X, Wu WK, Chan MT. Targeted Genotyping Identifies Two Susceptibility Loci in Bdnf Gene for Chronic Postsurgical Pain. Anesth Analg. 2016;122.

  10. Ho AMH, Karmakar MK, Ng SK, Wan S, Ng CSH, Wong RHL, Chan SKC, Joynt GM. Local anaesthetic toxicity after bilateral thoracic paravertebral block in patients undergoing coronary artery bypass surgery. Anaesth Intens Care. 2016;44(5):615-9.

  11. Ho J, Chan H, Wong SH, Wang MHT, Yu J, Xiao ZG, Liu XD, Choi G, Leung CCH, Wong WT, Li Z, Gin T, Chan MTV, Wu WKK. The involvement of regulatory non-coding RNAs in sepsis: a systematic review. Crit Care. 2016;20.

  12. Ho J, Yu J, Wong SH, Zhang L, Liu XD, Wong WT, Leung CCH, Choi G, Wang MHT, Gin T, Chan MTV, Wu WKK. Autophagy in sepsis: Degradation into exhaustion? Autophagy. 2016;12(7):1073-82.

  13. 13.          Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algul H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An ZY, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Banhegyi G, Bao HJ, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolome A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bedard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GMN, Behrns KE, Bejarano E, Belaid A, Belleudi F, Benard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Bockler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouche M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VMM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultman SJ, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Butikofer P, Caberlotto L, Cadwell K, Cahova M, Cai DS, Cai JJ, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao LZ, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LAM, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Cena V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EYW, Chan MTV,et al. . Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222.

  14. Konstantatos AH, Howard W, Story D, Mok LYH, Boyd D, Chan MTV   A randomised controlled trial of peri-operative pregabalin vs. placebo for video-assisted thoracoscopic surgery. Anaesthesia. 2016;71(2):192-7.

  15. Lai VKW, Lee A, Leung P, Chiu CH, Ho KM, Gomersall CD, Underwood MJ, Joynt GM. Patient and Family Satisfaction Levels in the Intensive Care Unit after Elective Cardiac Surgery. Anesth Analg. 2016;123:150-.

  16. Lai VKW, Lee A, Leung P, Chiu CH, Ho KM, Gomersall CD, Underwood MJ, Joynt GM. Patient and family satisfaction levels in the intensive care unit after elective cardiac surgery: study protocol for a randomised controlled trial of a preoperative patient education intervention. Bmj Open. 2016;6(6).

  17. Lee A, Samy W, Chiu CH, Chan SKC, Gin T, Chui PT. Determinants of Serum 25-Hydroxyvitamin D Concentrations and a Screening Test for Moderate-to-Severe Hypovitaminosis D in Chinese Patients Undergoing Total Joint Arthroplasty. J Arthroplasty. 2016;31(9):1921-6.

  18. Lei DW, Dong CG, Wu WKK, Dong AM, Li TT, Chan MTV, Zhou XR, Yuan HP. Lentiviral Delivery of Small Hairpin RNA Targeting Connective Tissue Growth Factor Blocks Profibrotic Signaling in Tenon's Capsule Fibroblasts. Invest Ophth Vis Sci. 2016;57(13):5171-80.

  19. Li XC, Wu WKK, Xing R, Wong SH, Liu YX, Fang XD, Zhang YL, Wang MY, Wang JQ, Li L, Zhou Y, Tang SW, Peng SL, Qiu KL, Chen LY, Chen KX, Yang HM, Zhang W, Chan MTV, Lu YY, Sung JJY, Yu J. Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability. Cancer Res. 2016;76(7):1724-32.

  20. Li Z, Shen JX, Chan MTV, Wu WKK. TUG1: a pivotal oncogenic long non-coding RNA of human cancers. Cell Proliferat. 2016;49(4):471-5.

  21. Li Z, Wong SH, Shen JX, Chan MTV, Wu WKK. The Role of MicroRNAS in Ankylosing Spondylitis. Medicine. 2016;95(14).

  22. Ling L, Gomersall CD, Samy W, Joynt GM, Leung CCH, Wong WT, Lee A. The Effect of a Freely Available Flipped Classroom Course on Health Care Worker Patient Safety Culture: A Prospective Controlled Study. J Med Internet Res. 2016;18(7).

  23. Milligan J, Lee A, Gill M, Weatherall A, Tetlow C, Garner AA. Performance comparison of improvised prehospital blood warming techniques and a commercial blood warmer. Injury. 2016;47(8):1824-7.

  24. Mrkobrada M, Hill MD, Chan MTV, Sigamani A, Cowan D, Kurz A, Sessler DI, Jacka M, Graham M, Dasgupta M, Dunlop V, Emery DJ, Gulka I, Guyatt G, Heels-Ansdell D, Murkin J, Pettit S, Sahlas DJ, Sharma M, Sharma M, Srinathan S, St John P, Tsai S, Gelb AW, O'Donnell M, Siu D, Chiu PWY, Sharath V, George A, Devereaux PJ. Covert stroke after non-cardiac surgery: a prospective cohort study. Brit J Anaesth. 2016;117(2):191-7.

  25. Myles PS, Chan MTV, Kasza J, Paech MJ, Leslie K, Peyton PJ, Sessler DI, Haller G, Beattie WS, Osborne C, Sneyd JR, Forbes A. Severe Nausea and Vomiting in the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II Trial. Anesthesiology. 2016;124(5):1032-40.

  26. Phua J, Joynt GM, Nishimura M, Deng YY, Myatra SN, Chan YH, Binh NG, Tan CC, Faruq MO, Arabi YM, Wahjuprajitno B, Liu SF, Hashemian SMR, Kashif W, Staworn D, Palo JE, Koh Y, Investigators AS, Care AC. Withholding and withdrawal of life-sustaining treatments in low-middle-income versus high-income Asian countries and regions. Intens Care Med. 2016;42(7):1118-27.

  27. Phua J, Joynt GM, Nishimura M, Deng YY, Myatra SN, Chan YH, Binh NG, Tan CC, Faruq MO, Arabi YM, Wahjuprajitno B, Liu SF, Hashemian SMR, Kashif W, Staworn D, Palo JE, Koh Y, Investigators AS, Clinical ACC. Withholding and withdrawal of life-sustaining treatments in low-middle-income versus high-income Asian countries and regions (vol 42, pg 1118, 2016). Intens Care Med. 2016;42(7):1202-.

  28. Rainer TH, Leung YK, Lee A, Chan PY, Cheng NM, Wong JK, Yan BP, Ahuja AT, Graham CA. Add-on tests for improving risk-stratification in emergency department patients with chest pain who are at low to moderate risk of 30-day major adverse cardiac events. Int J Cardiol. 2016;220:299-306.

  29. Roberts JA, Choi GYS, Joynt GM, Paul SK, Deans R, Peake S, Cole L, Stephens D, Bellomo R, Turnidge J, Wallis SC, Roberts MS, Roberts DM, Lassig-Smith M, Starr T, Lipman J. SaMpling Antibiotics in Renal Replacement Therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infect Dis. 2016;16.

  30. Shen J, Li ZJ, Li LF, Lu L, Xiao ZG, Wu WKK, Zhang L, Li MX, Hu W, Chan KM, Cho CH. Vascular-targeted TNF alpha and IFN gamma inhibits orthotopic colorectal tumor growth. J Transl Med. 2016;14.

  31. Sun Z, Yue Y, Leung CCH, Chan MTV, Gelb AW, Stroke SGP. Clinical diagnostic tools for screening of perioperative stroke in general surgery: a systematic review. Brit J Anaesth. 2016;116(3):328-38.

  32. Tai A, Corke C, Joynt GM, Griffith J, Lunn D, Tong PWY. A comparative study of tracheal diameter in Caucasian and Chinese patients. Anaesth Intens Care. 2016;44(6):719-23.

  33. Tam MKP, Wong WT, Gomersall CD, Tian Q, Ng SK, Leung CCH, Underwood MJ. A randomized controlled trial of 2 protocols for weaning cardiac surgical patients receiving adaptive support ventilation. J Crit Care. 2016;33:163-8.

  34. Tang SW, Wu WKK, Li XC, Wong SH, Wong N, Chan MTV, Sung JJY, Yu J. Stratification of Digestive Cancers with Different Pathological Features and Survival Outcomes by MicroRNA Expression. Sci Rep-Uk. 2016;6.

  35. Tsang DPF, Wu WKK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang WQ, Li MSM, Lau SS, Li XC, Lee SD, Yang YH, Lai PBS, Yu DY, Xu G, Lo KW, Chan MTV, Wang HT, Lee TL, Yu J, Wong N, Yip KY, To KF, Cheng ASL. Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-B in hepatocellular carcinoma. J Pathol. 2016;238(5):651-64.

  36. Tse AHW, Ling L, Joynt GM, Lee A. The Quality of Reporting in Pharmacokinetic Studies of Analgesics and Sedatives Delivered for More Than 24 Hours in Adult Intensive Care Patients: A Systematic Review. Anesth Analg. 2016;123:665-.

  37. Wang L, Hu T, Shen J, Zhang L, Li LF, Chan RLY, Li MX, Wu WKK, Cho CH. Miltirone induced mitochondrial dysfunction and ROS-dependent apoptosis in colon cancer cells. Life Sci. 2016;151:224-34.

  38. Wong SH, Gao QY, Tsoi KKF, Wu WKK, Tam LS, Lee N, Chan FKL, Wu JCY, Sung JJY, Ng SC. Effect of immunosuppressive therapy on interferon gamma release assay for latent tuberculosis screening in patients with autoimmune diseases: a systematic review and meta-analysis. Thorax. 2016;71(1):64-72.

  39. Wong SH, Ip M, Hawkey PM, Lo N, Hardy K, Manzoor S, Hui WWM, Choi KW, Wong RYK, Yung IMH, Cheung CSK, Lam KLY, Kwong T, Wu WKK, Ng SC, Wu JCY, Sung JJY, Lee N. High morbidity and mortality of Clostridium difficile infection and its associations with ribotype 002 in Hong Kong. J Infection. 2016;73(2):115-22.

  40. Wong WT, Lai VKW, Chee YE, Lee A. Fast-track cardiac care for adult cardiac surgical patients. Cochrane Db Syst Rev. 2016(9).

  41. Wu WKK, Chan MTV, Cheng ASL. A transcriptional-microRNA network for beta-catenin-driven stemness in hepatocellular carcinoma. Transl Cancer Res. 2016;5:S1408-S12.

  42. Wu WKK, Yu J, Chan MTV, To KF, Cheng ASL. Combinatorial epigenetic deregulation by Helicobacter pylori and Epstein-Barr virus infections in gastric tumourigenesis. J Pathol. 2016;239(3):245-9.

  43. Xin Y, Li Z, Chan MTV, Wu WKK. Circulating epigenetic biomarkers in melanoma. Tumor Biol. 2016;37(2):1487-92.

  44. Xin Y, Li Z, Shen JX, Chan MTV, Wu WKK. CCAT1: a pivotal oncogenic long non-coding RNA in human cancers. Cell Proliferat. 2016;49(3):255-60.

  45. Yu J, Wu WKK, Liang Q, Zhang N, He J, Li X, Zhang X, Xu L, Chan MTV, Ng SSM, Sung JJY. Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer. Oncogene. 2016;35(2):187-95.

  46. Yu L, Wu WKK, Gu CP, Zhong DS, Zhao XY, Kong Y, Lin QH, Chan MTV, Zhou ZT, Liu SW. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7(12):14693-707.

  47. Yu X, Li Z, Chan MTV, Wu WKK. The roles of microRNAs in Wilms' tumors. Tumor Biol. 2016;37(2):1445-50.

  48. Yu X, Li Z, Shen JX, Chan MTV, Wu WKK. Role of microRNAs in primary central nervous system lymphomas. Cell Proliferat. 2016;49(2):147-53.

  49. Zhang J, Critchley LAH, Lee DCW, Khaw KS, Lee SWY. The effect of head up tilting on bioreactance cardiac output and stroke volume readings using suprasternal transcutaneous Doppler as a control in healthy young adults. J Clin Monit Comput. 2016;30(5):519-26.

  50. Zhang L, Wu WKK, Gallo RL, Fang EF, Hu W, Ling TKW, Shen J, Chan RLY, Lu L, Luo XM, Li MX, Chan KM, Yu J, Wong VWS, Ng SC, Wong SH, Chan FKL, Sung JJY, Chan MTV, Cho CH. Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection. J Immunol. 2016;196(4):1799-809.

 

 
  1. Chan MTV, Gin T.   Delirium and cognitive decline after surgery: a randomised controlled trial of anaesthetic management to improve postoperative mental health outcome.   Hong Kong Med J 2015; 20 Suppl 7; 28-9.





  2. Chan MTV, Gin T.   Predicting postoperative cardiac complications using automated endothelial function test.   Hong Kong Med J 2015; 21 Suppl 6; 17-8.


  3. Chan MTV, Wu WKK, Tang RS.   Optimizing depth of sedation for colonoscopy.   Can J Anaesth 2015; 62(11); 1143-8. doi: 10.1007/s12630-015-0462-4.


  4. Chen X, Dong C, Law PT, Chan MTV, Su Z, Wang S, Wu WKK, Xu H.   MicroRNA-145 targets TRIM2 and exerts tumor-suppressing functions in epithelial ovarian cancer.   Gynecol Oncol 2015; 139(3); 513-9. doi: 10.1016/j.ygyno.2015.10.008.


  5. Cho CH, Yu J, Zhang L, Wu WKK.   The role of cathelicidin in control of Helicobacter pylori colonisation in the stomach.   Hong Kong Med J 2015; 21 Suppl 4; 17-9.


  6. Critchley LAH, Zhang J.   The pulmonary circulation: a significant factor in the performance of different thermodilution techniques.   Anesth Analg 2015; 121(1); 8-10. doi: 10.1213/ANE.0000000000000657.


  7. Dorhout Mees SM, Algra A, Wong GK, Poon WS, Bradford CM, Saver JL, Starkman S, Rinkel GJ, van den Bergh WM; writing groups of MASH-I, IMASH, MASH-II, MASH and FAST-MAG, van Kooten F, Dirven CM, van Gijn J, Vermeulen M, Rinkel GJ, Boet R, Chan MTV, Gin T, Ng SC, Zee BC, Al-Shahi Salman R, Boiten J, Kuijsten H, Lavados PM, van Oostenbrugge RJ, Vandertop WP, Finfer S, O'Connor A, Yarad E, Firth R, McCallister R, Harrington T, Steinfort B, Faulder K, Assaad N, Morgan M, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N.   Early Magnesium Treatment After Aneurysmal Subarachnoid Hemorrhage: Individual Patient Data Meta-Analysis.   Stroke 2015; 46(11); 3190-3. doi: 10.1161/STROKEAHA.115.010575.


  8. Ho AM, Critchley LAH, Leung JY, Kan PK, Au SS, Ng SK, Chan SK, Lam PK, Choi GY, Wai JK, Lee AP, Chan SO.   Introducing Final-Year Medical Students to Pocket-Sized Ultrasound Imaging: Teaching Transthoracic Echocardiography on a 2-Week Anesthesia Rotation.   Teach Learn Med 2015; 27(3); 307-13. doi: 10.1080/10401334.2015.1044657.


  9. Ho AM, Holcomb JB, Ng CS, Zamora JE, Karmakar MK, Dion PW.   The traditional vs "1:1:1" approach debate on massive transfusion in trauma should not be treated as a dichotomy.   Am J Emerg Med 2015; 33(10); 1501-4. doi: 10.1016/j.ajem.2015.06.065.


  10. Ho AM, Zamora JE, Holcomb JB, Ng CS, Karmakar MK, Dion PW.   The Many Faces of Survivor Bias in Observational Studies on Trauma Resuscitation Requiring Massive Transfusion.   Ann Emerg Med 2015; 66(1); 45-8. doi: 10.1016/j.annemergmed.2014.12.030.


  11. Hoste EA, Bagshaw SM, Bellomo R, Cely CM, Colman R, Cruz DN, Edipidis K, Forni LG, Gomersall CD, Govil D, Honoré PM, Joannes-Boyau O, Joannidis M, Korhonen AM, Lavrentieva A, Mehta RL, Palevsky P, Roessler E, Ronco C, Uchino S, Vazquez JA, Vidal Andrade E, Webb S, Kellum JA.   Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study.   Intensive Care Med 2015; 41(8); 1411-23. doi: 10.1007/s00134-015-3934-7.


  12. Hu T, Wang L, Zhang L, Lu L, Shen J, Chan RL, Li M, Wu WKK, To KK, Cho CH.   Sensitivity of apoptosis-resistant colon cancer cells to tanshinones is mediated by autophagic cell death and p53-independent cytotoxicity.   Phytomedicine 2015; 22(5); 536-44. doi: 10.1016/j.phymed.2015.03.010.


  13. Huang L, Critchley LAH, Zhang J.   Erratum to: Does using two Doppler cardiac output monitors in tandem provide a reliable trend line of changes for validation studies?   J Clin Monit Comput 2015.


  14. Huang L, Critchley LAH, Zhang J.   Major Upper Abdominal Surgery Alters the Calibration of Bioreactance Cardiac Output Readings, the NICOM, When Comparisons Are Made Against Suprasternal and Esophageal Doppler Intraoperatively.   Anesth Analg 2015; 121(4); 936-45. doi: 10.1213/ANE.0000000000000889.


  15. Hui DS, Chow BK, Lo T, Ng SS, Ko FW, Gin T, Chan MTV.   Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask.   Chest 2015; 147(5); 1336-43. doi: 10.1378/chest.14-1934.


  16. Joynt GM, Lipman J, Hartog C, Guidet B, Paruk F, Feldman C, Kissoon N, Sprung CL.   The Durban World Congress Ethics Round Table IV: health care professional end-of-life decision making.   J Crit Care 2015; 30(2); 224-30. doi: 10.1016/j.jcrc.2014.10.011.


  17. Karmakar MK, Li JW, Kwok WH, Hadzic A.   Ultrasound-guided lumbar plexus block using a transverse scan through the lumbar intertransverse space: a prospective case series.   Reg Anesth Pain Med 2015; 40(1); 75-81. doi: 10.1097/AAP.0000000000000168.


  18. Karmakar MK, Sala-Blanch X, Songthamwat B, Tsui BC.   Benefits of the costoclavicular space for ultrasound-guided infraclavicular brachial plexus block: description of a costoclavicular approach.   Reg Anesth Pain Med 2015; 40(3); 287-8. doi: 10.1097/AAP.0000000000000232.


  19. Khaw KS, Lee SW, Ngan Kee WD, Law LW, Lau TK, Ng FF, Leung TY.   Randomized trial of anaesthetic interventions in external cephalic version for breech presentation.   Br J Anaesth 2015; 114(6); 944-50. doi: 10.1093/bja/aev107.


  20. Lee A, Chan SK, Fan LT.   Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting.   Cochrane Database Syst Rev 2015; 11; CD003281. doi: 10.1002/14651858.CD003281.pub4.


  21. Lee A, Chan SK, Samy W, Chiu CH, Gin T.   Effect of Hypovitaminosis D on Postoperative Pain Outcomes and Short-Term Health-Related Quality of Life After Knee Arthroplasty: A Cohort Study.   Medicine (Baltimore) 2015; 94(42); e1812. doi: 10.1097/MD.0000000000001812.


  22. Lee A, Chui PT, Chiu CH, Tan PE, Tam TP, Samy W, Tong PW, Critchley LAH, Gin T.   Risk of perioperative respiratory complications and postoperative morbidity in a cohort of adults exposed to passive smoking.   Ann Surg 2015; 261(2); 297-303. doi: 10.1097/SLA.0000000000000544.


  23. Leslie K, Myles PS, Kasza J, Forbes A, Peyton PJ, Chan MTV, Paech MJ, Sessler DI, Beattie WS, Devereaux PJ, Wallace S.   Nitrous Oxide and Serious Long-term Morbidity and Mortality in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II Trial.   Anesthesiology 2015; 123(6); 1267-80. doi: 10.1097/ALN.0000000000000908.


  24. Leung JY, Critchley LAH, Yung AL, Kumta SM.   Evidence of virtual patients as a facilitative learning tool on an anesthesia course.   Adv Health Sci Educ Theory Pract 2015; 20(4); 885-901. doi: 10.1007/s10459-014-9570-0.


  25. Li CW, Liao CH, Huang X, Chan MTV.   Orchids (Oncidium and Phalaenopsis).   Methods Mol Biol 2015; 1224; 331-46. doi: 10.1007/978-1-4939-1658-0_26.


  26. Li H, Critchley LAH, Zhang J.   Does using two Doppler cardiac output monitors in tandem provide a reliable trend line of changes for validation studies?   J Clin Monit Comput 2015.


  27. Li X, Li JW, Ho AM, Karmakar MK.   Age-related differences in the quantitative echo texture of the median nerve.   J Ultrasound Med 2015; 34(5); 797-804. doi: 10.7863/ultra.34.5.797.


  28. Li Z, Shen J, Li Q, Chan MTV, Wu WKK.   Drug Fever Induced by Piperacillin/Tazobactam in a Scoliosis Patient: A Case Report.   Medicine (Baltimore) 2015; 94(46); e1875. doi: 10.1097/MD.0000000000001875.


  29. Li Z, Yu X, Shen J, Chan MTV, Wu WKK.   MicroRNA in intervertebral disc degeneration.   Cell Prolif 2015; 48(3); 278-83. doi: 10.1111/cpr.12180.


  30. Li Z, Yu X, Shen J, Law PT, Chan MTV, Wu WKK.   MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer.   Oncotarget 2015; 6(16); 13914-21.


  31. Li Z, Yu X, Shen J, Liu Y, Chan MTV, Wu WKK.   MicroRNA dysregulation in rhabdomyosarcoma: a new player enters the game.   Cell Prolif 2015; 48(5); 511-6. doi: 10.1111/cpr.12199.


  32. Li Z, Yu X, Shen J, Wu WKK, Chan MTV.   MicroRNA expression and its clinical implications in Ewing's sarcoma.   Cell Prolif; 48(1); 1-6. doi: 10.1111/cpr.12160.


  33. Li Z, Yu X, Wang Y, Shen J, Wu WKK, Liang J, Feng F.   By downregulating TIAM1 expression, microRNA-329 suppresses gastric cancer invasion and growth.   Oncotarget 2015; 6(19); 17559-69.


  34. Lin CS, Chen JJ, Huang YT, Chan MTV, Daniell H, Chang WJ, Hsu CT, Liao DC, Wu FH, Lin SY, Liao CF, Deyholos MK, Wong GK, Albert VA, Chou ML, Chen CY, Shih MC.   The location and translocation of ndh genes of chloroplast origin in the Orchidaceae family.   Sci Rep 2015; 5; 9040. doi: 10.1038/srep09040.


  35. Liu X, Dong C, Jiang Z, Wu WKK, Chan MTV, Zhang J, Li H, Qin K, Sun X.   MicroRNA-10b downregulation mediates acute rejection of renal allografts by derepressing BCL2L11.   Exp Cell Res 2015; 333(1); 155-63. doi: 10.1016/j.yexcr.2015.01.018.


  36. Liu X, Tian Y, Meng Z, Chen Y, Ho IH, Choy KW, Lichtner P, Wong SH, Yu J, Gin T, Wu WKK, Cheng CH, Chan MTV.   Up-regulation of Cathepsin G in the Development of Chronic Postsurgical Pain: An Experimental and Clinical Genetic Study.   Anesthesiology; 123(4); 838-50. doi: 10.1097/ALN.0000000000000828.


  37. Lu L, Li ZJ, Li LF, Wu WKK, Shen J, Zhang L, Chan RL, Yu L, Liu YW, Ren SX, Chan KM, Cho CH.   Vascular-targeted TNFa improves tumor blood vessel function and enhances antitumor immunity and chemotherapy in colorectal cancer.   J Control Release 2015; 210; 134-46. doi: 10.1016/j.jconrel.2015.05.282.


  38. Luo MX, Wong SH, Chan MTV, Yu L, Yu SS, Wu F, Xiao Z, Wang X, Zhang L, Cheng AS, Ng SS, Chan FK, Cho CH, Yu J, Sung JJ, Wu WKK.   Autophagy Mediates HBx-Induced Nuclear Factor-?B Activation and Release of IL-6, IL-8, and CXCL2 in Hepatocytes.   J Cell Physiol 2015; 230(10); 2382-9. doi: 10.1002/jcp.24967.


  39. McIlroy DR, Chan MTV, Wallace SK, Grover A, Koo EG, Ma J, Symons JA, Myles PS.   Is Preoperative Endothelial Dysfunction a Potentially Modifiable Risk Factor for Renal Injury Associated With Noncardiac Surgery?   J Cardiothorac Vasc Anesth 2015; 29(5); 1220-8. doi: 10.1053/j.jvca.2015.05.116.


  40. Moralli D, Nudel R, Chan MTV, Green CM, Volpi EV, Benítez-Burraco A, Newbury DF, García-Bellido P.   Language impairment in a case of a complex chromosomal rearrangement with a breakpoint downstream of FOXP2.   Mol Cytogenet 2015; 8; 36. doi: 10.1186/s13039-015-0148-1.


  41. Mu JL, Lee A, Joynt GM.   Pharmacologic agents for the prevention and treatment of delirium in patients undergoing cardiac surgery: systematic review and metaanalysis.   Crit Care Med 2015; 43(1); 194-204. doi: 10.1097/CCM.0000000000000673.


  42. Myles PS, Peyton P, Chan MTV, Leslie K; ENIGMA-II investigators.   Nitrous oxide in general anaesthesia - Authors' reply. Lancet 2015; 385(9966); 417-8. doi: 10.1016/S0140-6736(15)60152-0.


  43. Nakatsu G, Li X, Zhou H, Sheng J, Wong SH, Wu WKK, Ng SC, Tsoi H, Dong Y, Zhang N, He Y, Kang Q, Cao L, Wang K, Zhang J, Liang Q, Yu J, Sung JJ.   Gut mucosal microbiome across stages of colorectal carcinogenesis.   Nat Commun 2015; 6; 8727. doi: 10.1038/ncomms9727.


  44. Ngan Kee WD, Lee SW, Ng FF, Tan PE, Khaw KS.   Randomized double-blinded comparison of norepinephrine and phenylephrine for maintenance of blood pressure during spinal anesthesia for cesarean delivery.   Anesthesiology 2015; 122(4); 736-45. doi: 10.1097/ALN.0000000000000601.


  45. Ngan Kee WD, Lee SW, Ng FF, Tan PE, Khaw KS.   Randomized double-blinded comparison of norepinephrine and phenylephrine for maintenance of blood pressure during spinal anesthesia for cesarean delivery.   Anesthesiology 2015; 122(4); 736-45. doi: 10.1097/ALN.0000000000000601.


  46. Phua J, Joynt GM, Nishimura M, Deng Y, Myatra SN, Chan YH, Binh NG, Tan CC, Faruq MO, Arabi YM, Wahjuprajitno B, Liu SF, Hashemian SM, Kashif W, Staworn D, Palo JE, Koh Y; ACME Study Investigators and the Asian Critical Care Clinical Trials Group.   Withholding and withdrawal of life-sustaining treatments in intensive care units in Asia.   JAMA Intern Med 2015; 175(3); 363-71. doi: 10.1001/jamainternmed.2014.7386.


  47. Phua J, Joynt GM, Nishimura M, Deng Y, Myatra SN, Chan YH, Binh NG, Tan CC, Faruq MO, Arabi YM, Wahjuprajitno B, Liu SF, Hashemian SM, Kashif W, Staworn D, Palo JE, Koh Y; ACME Study Investigators and the Asian Critical Care Clinical Trials Group.   Withholding and withdrawal of life-sustaining treatments in intensive care units in Asia.   JAMA Intern Med 2015; 175(3); 363-71. doi: 10.1001/jamainternmed.2014.7386.


  48. Ruhlman TA, Chang WJ, Chen JJ, Huang YT, Chan MTV, Zhang J, Liao DC, Blazier JC, Jin X, Shih MC, Jansen RK, Lin CS.   NDH expression marks major transitions in plant evolution and reveals coordinate intracellular gene loss.   BMC Plant Biol 2015; 15; 100. doi: 10.1186/s12870-015-0484-7.


  49. Shen J, Xiao Z, Wu WKK, Wang MH, To KF, Chen Y, Yang W, Li MS, Shin VY, Tong JH, Kang W, Zhang L, Li M, Wang L, Lu L, Chan RL, Wong SH, Yu J, Chan MTV, Chan FK, Sung JJ, Cheng AS, Cho CH.   Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis.   Cancer Res 2015; 75(4); 754-65. doi: 10.1158/0008-5472.CAN-14-1301.


  50. Short TG, Leslie K, Chan MTV, Campbell D, Frampton C, Myles P.   Rationale and Design of the Balanced Anesthesia Study: A Prospective Randomized Clinical Trial of Two Levels of Anesthetic Depth on Patient Outcome After Major Surgery.   Anesth Analg 2015; 121(2); 357-65. doi: 10.1213/ANE.0000000000000797.


  51. Shulman MA, Myles PS, Chan MTV, McIlroy DR, Wallace S, Ponsford J.   Measurement of disability-free survival after surgery. Anesthesiology 2015; 122(3); 524-36. doi: 10.1097/ALN.0000000000000586.


  52. Sivashanmugam T, Ray S, Ravishankar M, Jaya V, Selvam E, Karmakar MK.   Randomized Comparison of Extrafascial Versus Subfascial Injection of Local Anesthetic During Ultrasound-Guided Supraclavicular Brachial Plexus Block.   Reg Anesth Pain Med 2015; 40(4); 337-43. doi: 10.1097/AAP.0000000000000264.


  53. Sprung CL, Hawryluck L, De Robertis E, Joynt GM, McDermid RC, Avidan A.   Reply: The Worldwide End-of-Life Practice for Patients in Intensive Care Units Study: Adding Africa.   Am J Respir Crit Care Med 2015; 192(6); 769-70. doi: 10.1164/rccm.201506-1213LE.


  54. Wang L, Hu T, Shen J, Zhang L, Chan RL, Lu L, Li M, Cho CH, Wu WKK.   Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer.   Phytomedicine 2015; 22(12); 1079-87. doi: 10.1016/j.phymed.2015.08.009.


  55. Whitlock RP, Devereaux PJ, Teoh KH, Lamy A, Vincent J, Pogue J, Paparella D, Sessler DI, Karthikeyan G, Villar JC, Zuo Y, Avezum Á, Quantz M, Tagarakis GI, Shah PJ, Abbasi SH, Zheng H, Pettit S, Chrolavicius S, Yusuf S; SIRS Investigators.   Methylprednisolone in patients undergoing cardiopulmonary bypass (SIRS): a randomised, double-blind, placebo-controlled trial.   Lancet 2015; 386(10000); 1243-53. doi: 10.1016/S0140-6736(15)00273-1.


  56. Wong GK, Chan DY, Siu DY, Zee BC, Poon WS, Chan MTV, Gin T, Leung M; HDS-SAH Investigators.   High-dose simvastatin for aneurysmal subarachnoid hemorrhage: multicenter randomized controlled double-blinded clinical trial.   Stroke; 46(2); 382-8. doi: 10.1161/STROKEAHA.114.007006.


  57. Wong GK, Wong A, Zee BC, Poon WS, Chan MTV, Gin T, Siu DY, Mok VC.   Cognitive outcome in acute simvastatin treatment for aneurysmal subarachnoid hemorrhage: A propensity matched analysis.   J Neurol Sci. 2015; 358(1-2); 58-61. doi: 10.1016/j.jns.2015.08.013.


  58. Wong WT, Choi G, Gomersall CD, Lipman J.   To increase or decrease dosage of antimicrobials in septic patients during continuous renal replacement therapy: the eternal doubt.   Curr Opin Pharmacol 2015; 24; 68-78. doi: 10.1016/j.coph.2015.07.003. Epub 2015 Oct 28.


  59. Xin Y, Li Z, Chan MTV, Wu WKK.   Circulating epigenetic biomarkers in melanoma.   Tumour Biol 2015.


  60. Yu X, Li Z, Chan MTV, Wu WKK.   microRNA deregulation in keloids: an opportunity for clinical intervention?   Cell Prolif; 48(6); 626-30. doi: 10.1111/cpr.12225.


  61. Yu X, Li Z, Chan MTV, Wu WKK.   PAQR3: a novel tumor suppressor gene.   Am J Cancer Res 2015; 5(9); 2562-8.


  62. Yu X, Li Z, Chan MTV, Wu WKK.   The roles of microRNAs in Wilms' tumors.   Tumour Biol 2015.


  63. Yu X, Li Z, Yu J, Chan MTV, Wu WKK. MicroRNAs predict and modulate responses to chemotherapy in colorectal cancer.   Cell Prolif 2015; 48(5); 503-10. doi: 10.1111/cpr.12202.


  64. Zhang J, Critchley LAH, Huang L.   Five algorithms that calculate cardiac output from the arterial waveform: a comparison with Doppler ultrasound.   Br J Anaesth 2015; 115(3); 392-402. doi: 10.1093/bja/aev254.


  65. Zhang J, Critchley LAH, Huang L.   The effect of aorta unfolding and remodelling on oesophageal Doppler readings as probe depth is varied.   Br J Anaesth 2015; 115(5); 708-15. doi: 10.1093/bja/aev343.


  66. Zhu F, Gomersall CD, Ng SK, Underwood MJ, Lee A.   A randomized controlled trial of adaptive support ventilation mode to wean patients after fast-track cardiac valvular surgery.   Anesthesiology 2015; 122(4); 832-40. doi: 10.1097/ALN.0000000000000589.



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

The Chinese University of Hong Kong   |  Department of Anaesthesia and Intensive Care 
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