Vice-Chancellor Assistant Professor
Room G58 Science Centre
(852) 3943 5868
https://xinglong-zhang.github.io
Education
| 2020 | Postdoctoral Scholar, Division of Chemistry and Chemical Engineering, California Institute of Technology (Caltech), USA | |
| 2019 | Doctor of Philosophy, University of Oxford, UK | |
| 2016 | Master of Science, Theoretical and Computational Chemistry (Distinction), University of Oxford, UK | |
| 2014 | Bachelor of Arts, Natural Sciences Tripos (First Class Honours), University of Cambridge, UK | |
Positions
| Since 2024 | Vice-Chancellor Assistant Professor, The Chinese University of Hong Kong |
| 2020-2025 | Research Scientist, IHPC, A*STAR, Singapore |
| 2014-2015 | Laboratory Officer, IBN, A*STAR, Singapore |
Professional Affiliations
| Ad hoc | Peer reviewer for Nat. Chem., Nat. Commun., J. Am. Chem. Soc., Advanced Science, Digital Discovery, Chem. Sci., J. Org. Chem., ACS Omega etc. |
| Since 01/2024 | Member, International Union of Pure and Applied Chemistry (IUPAC) |
| Since 03/2022 | Member, American Chemical Society (ACS), USA |
| Since 12/2017 | Member, Royal Society of Chemistry (RSC), UK |
| Since 07/2017 | Member, World Association of Theoretical and Computational Chemists (WATOC) |
Research Interests
| We are broadly interested in applying computational tools to understand the mechanisms for various catalytic chemical reactions. Areas of interests include C–H activation, small-molecule (CO2, N2, H2) activation and asymmetric catalysis. We are also interested in applying machine learning techniques to tackle traditionally challenging chemical problems such as dynamic and entropic effects that are hard to capture accurately with static DFT. We also aim to apply coding and workflow development to facilitate high-throughput quantum chemical studies and machine learning applications, with the goal of streamlining computational research practices. |
Honors and Awards
| 2023 | ASEAN-Republic of Korea Next ASEAN Innovator Finalist |
| 2018 | The Leathersellers’ Company Scholarship, University of Oxford, UK |
| 2017 | New College Graduate Travel/Research Grant, University of Oxford, UK |
| 2017-2019 | Stipendiary Lectureship in Physical Chemistry (undergraduate teaching), University of Oxford, UK |
| 2015 | National Science Scholarship (PhD), A*STAR, Singapore |
| 2009 | National Science Scholarship (BS), A*STAR, Singapore |
Representative Publications
| 1. | Tan, T-D.; Tee, K. Z.; Luo, X.; Qian, P-C.; Zhang, X.;* Koh, M. J.* Kinetically controlled Z-alkene synthesis using iron-catalysed allene dialkylation. Nat. Synth., 2024, https://doi.org/10.1038/s44160-024-00658-7. |
| 2. | Tan. T.-D.; Serviano, J.; Luo, X.; Qian, P.-C.; Holland P.;* Zhang, X.;* Koh, M. J.* Congested C(sp3)-rich Architectures by Iron-catalyzed Conjunctive Alkylation. Nat. Catal. 2024, 7, 321. |
| 3. | Das, J.; Ali, W.; Ghosh, A.; Pal, T.; Mandal, A.; Chitrala, T.; Dutta, S.; Pothikumar, R.; Ge, H.;* Zhang, X.;* Maiti, D.* Access to Unsaturated Bicyclic Lactones by Overriding Conventional C(sp3)–H Site Selectivity. Nat. Chem. 2023, 15, 1626. (Highlighted by Synform 2024/04, A61–A65 and Synfacts 2024; 20(03): 0259.) |
| 4. | Wei, L.; Li, J.; Zhao, Y.; Zhou, Q.; Wei, Z.; Chen, Y.; Zhang, X.;* Yang, X.* Chiral Phosphoric Acid Catalyzed Asymmetric Hydrolysis of Biaryl Oxazepines for the Synthesis of Axially Chiral Biaryl Amino Phenol Derivatives. Angew. Chem. Int. Ed. 2023, e202306864. |
| 5. | Chen, B. W. J. *; Zhang, X.;* Zhang, J. Accelerating Explicit Solvent Models of Heterogeneous Catalysts with Machine Learning Interatomic Potentials. Chem. Sci. 2023, 14, 8338. |
| 6. | Sinha, S. K., Panja, S.; Grover, J.; Hazra, P. S.; Pandit, S.; Bairagi, Y.; Zhang, X.;* Maiti, D.* Dual Ligand Enabled No n-Directed C–H Chalcogenation of Arenes and Heteroarenes. J. Am. Chem. Soc., 2022, 144, 27, 12032 |
| 7. | Deng, R.; Wu, S., Chengli Mou, C.; Liu, J.; Zheng, P.;* Zhang, X.;* Chi, Y. R.* Carbene- Catalyzed Enantioselective Sulfonylation of Enone Aryl Aldehydes: A New Mode of Breslow Intermediate Oxidation. J. Am. Chem. Soc., 2022, 144, 12, 5441. |
| 8. | Zhang, X.; Paton, R. S.* Stereoretention in Styrene Heterodimerisation Promoted by One- Electron Oxidants. Chem. Sci., 2020, 11, 9309. |
| 9. | Achar, T. K.; †Zhang, X.; †Mondal, R.; Shanavas, M. S.; Maity, S.; Pal, N.; Paton, R. S.;* Maiti, D.* Palladium-Catalyzed Directed meta-Selective C–H Allylation of Arenes: Unactivated Internal Olefins as Allyl Surrogates. Angew. Chem. Int. Ed., 2019, 58, 10353. |
| 10. | Porey, S.; †Zhang, X.; †Bhowmick, S.; Singh, V. K. ; Guin, S.; Paton, R. S.;* Maiti, D.* An Alkyne Linchpin Strategy for Drug:Pharmacophore Conjugation: Experimental and Computational Realization of a meta-selective Inverse Sonogashira Coupling. J. Am. Chem. Soc., 2020, 142, 8, 3762. |
Major Research Grants
Research Grants:
| 1. | 2022 Manufacturing, Trade and Connectivity (MTC) Young Individual Research Grant (YIRG), Singapore, as PI, S$309,400 |
| 2. | 2021 A*STAR Career Development Fund, Singapore, as PI, S$234,000 |
Computational Research Grants:
| 1. | National Supercomputing Centre (NSCC), Singapore, total core-hours granted: 8,640,000 |
| 2. | Advanced Cyberinfrastructure Coordination Ecosystem: Services & Support (ACCESS), USA, total core-hours granted: 966,000 |
last update:7-June-2024