"AllPombeData_MedianNormalized_AfterAveragingReplicates_Working.Rdata" contains real data sets.
"BIOGRID.txt" records gene interactions in yeast from BioGrid.
"SPname.csv" collects gene names under different rules.

R codes are constituted by 3 parts.

The first one is "1_make_data.R". 
In this part, synthesized data sets are generated and saved as "data_train&test1.RData" and "data_test2.RData", 

The second one is "2_all_model_fitting.R".
In this part, model fitting process is completed and divided into 6 modules.
Each module corresponds to one model according to the order as  in main paper, i.e. 
1.our method, 2.traditional linear model, 3.classical linear model, 4.non-smooth ODE model, 5.smoothed ODE model and 6.classical ODE model.

The third one is "3_classification.R".
In this part, XGBoost and coefficient of determination are used to classify the fitting results of all models. 





