中大職務
醫學院助理院長 (外務)
化學病理學系教授
專業範疇
- 化學病理學
- 分子診斷學
- 分子病理學
- 遺傳學
- 基因組學
- 科創企業發展
教育及資歷
MBBS (HKU), MRCP (UK), FRCPA (Australia), PhD (CUHK), FHKCPath, FHKAM
專注研究
- 開發基於血漿DNA的創新診斷測試
更多資訊
獎項及榮譽
- 國家教育部高等學校科學研究優秀成果獎 - 技術發明獎二等獎, 2019
- 中國臨床腫瘤學會 (CSCO) 年度成就獎, 2018
- 首屆羅鷹石慈慧學者獎, 2018
- 首屆Arnold Chan講師(為紀念加拿大議會議員Arnold Chan), 2018
- 新英倫醫學雜誌 (NEJM)「最受矚目研究文章」之第一和通訊作者, 2017
- 香港醫學專科學院最佳原創研究獎, 2009
專業服務
- 食物及衞生局醫療衞生研究基金 : 資助審查委員會和專家諮詢小組委員
- Expert Review for Molecular Diagnostics 編輯委員會成員
- 香港認可處 (醫療實驗室) 評審員
部分論文 (只有英文版本)
- Lam WKJ*, Jiang P*, Chan KCA*, Peng W, Shang H, Heung MMS, Cheng SH, Zhang H, Tse OYO, Raghupathy R, Ma BBY, Hui EP, Chan ATC, Woo JKS, Chiu RWK, Lo YMD. Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases. Nat Commun 2019;10:3256. (*co-first authors)
- King AD, Woo JKS, Ai QY, Chan JSM, Lam WKJ, Tse IOL, Bhatia KS, Zee BCY, Hui EP, Ma BBY, Chiu RWK, Van Hasselt AC, Chan ATC, Lo YMD, Chan KCA. Complementary roles of MRI and endoscopic examination in the early detection of nasopharyngeal carcinoma. Ann Oncol 2019. doi: 10.1093/annonc/mdz106.
- Chan ATC, Hui EP, Ngan RKC, Tung SY, Cheng ACK, Ng WT, Lee VHF, Ma BBY, Cheng HC, Wong FCS, Loong HHF, Tong M, Poon DMC, Ahuja AT, King AD, Wang K, Mo F, Zee BCY, Chan KCA, Lo YMD. Analysis of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Cancer After Chemoradiation to Identify High-Risk Patients for Adjuvant Chemotherapy: A Randomized Controlled Trial. J Clin Oncol 2018:JCO2018777847.
- Gai W, Ji L, Lam WKJ, Sun K, Jiang P, Chan AWH, Wong J, Lai PBS, Ng SSM, Ma BBY, Wong GLH, Wong VWS, Chan HLY, Chiu RWK, Lo YMD, Chan KCA. Liver- and Colon-Specific DNA Methylation Markers in Plasma for Investigation of Colorectal Cancers with or without Liver Metastases. Clin Chem 2018;64(8):1239-1249.
- Chan KCA, Chu SWI, Lo YMD. Ambient Temperature and Screening for Nasopharyngeal Cancer. N Engl J Med2018;378:962-963.
- Lam WKJ*, Jiang P*, Chan KCA*, Cheng SH, Zhang H, Peng W, Tse OYO, Tong YK, Gai W, Zee BCY, Ma BBY, Hui EP, Chan ATC, Woo JKS, Chiu RWK, Lo YMD. Sequencing-based counting and size profiling of plasma Epstein-Barr virus DNA enhance population screening of nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 2018;115:E5115-24. (*co-first authors)
- Chan KCA, Woo JKS, King A, Zee BCY, Lam WKJ, Chan SL, Chu SWI, Mak C, Tse IOL, Leung SYM, Chan G, Hui EP, Ma BBY, Chiu RWK, Leung SF, van Hasselt AC, Chan ATC, Lo YMD. Analysis of Plasma Epstein-Barr Virus DNA to Screen for Nasopharyngeal Cancer. N Engl J Med 2017;377:513-522.
- Chan KCA, Jiang P, Sun K, Cheng YK, Tong YK, Cheng SH, Wong AI, Hudecova I, Leung TY, Chiu RW, Lo YM. Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends.Proc Natl Acad Sci U S A 2016;113:E8159-6
- Jiang P*, Chan CW*, Chan KCA*, Cheng SH, Wong J, Wong VW, Wong GL, Chan SL, Mok TS, Chan HL, Lai PB, Chiu RW, Lo YM. Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients.Proc Natl Acad Sci U S A 2015;112:E1317-25.(*co-first authors)
- Chan KCA, Jiang P, Zheng YW, Liao GJ, Sun H, Wong J, Siu SS, Chan WC, Chan SL, Chan AT, Lai PB, Chiu RW, Lo YMD.Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing.Clin Chem 2013;59:211-24.