The Chinese University of Hong Kong

Advanced Biophotonics Imaging Laboratory
(ABI Lab)


2023


ER stress aggravates diaphragm weakness through activating PERK/JNK signaling in obesity hypoventilation syndrome


Xiang X, Zhu Y, Pan X, Xin W, Chen J, Tang W, Guo R, Yuan W, He X, Zhou L, Ren Z, Wen S, Wang H, Lu T, Li S, Chen T, Zhou Y, Dou Z, Cai M, Zhang X, Chen Y, Shi G

Obesity, 2023; 31 (8), 2076-2089

Unraveling the complexity of Optical Coherence Tomography image segmentation using machine and deep learning techniques: A review


Nawaz M, Uvaliyev A, Bibi K, Wei H, Abaxi SMD, Masood A, Shi P, Ho HP, Yuan W

Computerized Medical Imaging and Graphics, 2023; 108:102269

Rectifying Noisy Labels with Sequential Prior: Multi-Scale Temporal Feature Affinity Learning for Robust Video Segmentation


Cui B, Zhang M, Xu M, Wang A, Yuan W, Ren H

arXiv:2307.05898

Analysis of the D-shaped PCF-based SPR sensor using Resonance Electron Relaxation and Fourier domain method


Luo W, Li X, Abbasi SA, Zhu S, Ho HP Yuan W

Optics and Lasers in Engineering 166, 107588

Ultrasensitive and Specific Clustered Regularly Interspaced Short Palindromic Repeats Empowered a Plasmonic Fiber Tip System for Amplification-Free Monkeypox Virus Detection and Genotyping


Chen Y, Chen Z, Li T, Qiu M, Zhang J, Wang Y, Yuan W, Ho HP, Al-Hartomy O, Wageh S, Al-Sehemi AG, Shi X, Li J, Xie Z, Li X, Zhang H

ACS Nano 2023; 17, 13, 12903–12914

Generalist Vision Foundation Models for Medical Imaging: A Case Study of Segment Anything Model on Zero-Shot Medical Segmentation


Shi P, Qiu J, Abaxi SMD, Wei H, Lo FPW, Yuan W

Diagnostics 2023; 13(11), 1947

Design and Evaluation of a Flexible Sensorized Robotic OCT Neuroendoscope


Yan J, Chen P, Xue J, Xu C, Qiu Y, Fang H, Lu Y, Wong GKC, Liu YH, Yuan W, Cheng SS

[ISMR 2023]

LiDeOCTNet: A Lightweight OCT-aware Framework for Segmentation of Irregularly Layered Tissue Structures


Abaxi SMD, Nawaz M, Shi P, Wei H, Abbasi SA, Yuan W

TechRxiv:22308655

Electrically switchable and tunable infrared light modulator based on functional graphene metasurface


Luo W, Abbasi SA, Zhu S, Li X, Ho HP, Yuan W

Nanophotonics 2023; 12(9), 1797-1807

Large AI Models in Health Informatics: Applications, Challenges, and the Future


Qiu J, Li L, Sun J, Peng J, Shi P, Zhang R, Dong Y, Lam K, Lo FPW, Xiao B, Yuan W, Xu D, Lo B

arXiv:2303.11568

Fiber-optic devices for sensing, manipulating, and imaging cells in vitro and in vivo


Zhu S, Zeng S, Wang Y, Ho HP, Yuan W

Microfluidic Biosensors, 2023; 313-342

2022


Real-Time Detection of Circulating Tumor Cells in Bloodstream Using Plasmonic Fiber Sensors


Zhu S, Xie Z, Chen Y, Liu S, Kwan YW, Zeng S, Yuan W, Ho HP

Biosensors, 2022; 12(11), 968

An Optimization Method for Ultrahigh-resolution Vis-OCT Imaging


Wang J, Xu C, Zhu S, Yuan W

[TENCON 2022]

Atomically Thin Nanomaterials-Enhanced Plasmonic Sensors Operating in Near-Infrared


Zhu S, Yuan W, Crunteanu A, Jaffiol R, Ho HP, Zeng S

[TENCON 2022]

Direct Visualization and Quantitative Imaging of Small Airway Anatomy In Vivo Using Deep Learning Assisted Diffractive OCT


Yuan W, Thiboutot J, Park HC, Li A, Loube J, Mitzner W, Yarmus L, Brown RH, Li XD

IEEE Trans Biomed Eng, 2022

Visualization and Validation of The Microstructures in The Airway Wall in vivo Using Diffractive Optical Coherence Tomography


Thiboutot J*, Yuan W*, Park HC, Li D, Loube J, Mitzner W, Yarmus L, Li XD, Brown RH

Academic radiology, 2022

In vivo assessment of inflammatory bowel disease in rats with ultrahigh-resolution colonoscopic OCT


Yuan W, Feng Y, Chen D, Gharibani P, Chen JD, Yu H, Li XD

Biomedical Optics Express, 2022; 13(4):2091-2102

Integrated scanning spectrometer with a tunable micro-ring resonator and an arrayed waveguide grating


Zhang Z, Wang Y, Wang J, YI D, Chan D, Yuan W, Tsang H

Photonics Research, 2022

2021


Label-free imaging of human brain tissue at subcellular resolution for potential rapid intra-operative assessment of glioma surgery


Chen D, Nauen DW, Park HC, Li D, Yuan W, Li A, Guan H, Kut C, Chaichana KL, Bettegowda C, Quiñones-Hinojosa A, Li XD

Theranostics 2021; 11(15):7222-7234

2020


In vivo assessment of vascular-targeted photodynamic therapy effects on tumor microvasculature using ultrahigh-resolution functional optical coherence tomography


Chen D*, Yuan W*, Park HC, Li XD

Biomedical Optics Express, 2020; 11(8):4316-4325.

Theranostic OCT microneedle for fast ultrahigh-resolution deep-brain imaging and efficient laser ablation in vivo


Yuan W, Chen D, Sarabia-Estrada R, Guerrero- Cázares H, Li D, Quiñones-Hinojosa A, Li XD

Science Advances, 2020; 6(15), eaaz9664.

2019


Ultralow-voltage electrothermal MEMS based fiber-optic scanning probe for forward-viewing endoscopic OCT


Park HC, Zhang X, Yuan W, Zhou L, Xie H, Li XD

Optics Letters, 2019; 44(9): 2232-2235

Parallel deep neural networks for endoscopic OCT image segmentation


Li D, Wu J, He Y, Yao X, Chen D, Park HC, Yuan W, Prince J, Li XD

Biomedical Optics Express, 2019; 10(3):1126-1135

Current advances in COPD imaging


Thiboutot J, Yuan W, Park HC, Lerner AD, Mitzner W, Yarmus LB, Li XD, Brown R

Academic Radiology, 2019; 26(3): 335-343

2018


Super-achromatic optical coherence tomography capsule for ultrahigh-resolution imaging of esophagus


Li K, Liang W, Mavadia-Shukla J, Park HC, Li D, Yuan W, Wan S, Li XD,

Journal of Biophotonics, 2018; 12(3): e201800205

Robust layer segmentation of esophageal OCT images based on graph search using edge-enhanced weights


Gan M, Wang C, Yang T, Yang N, Zhang M, Yuan W, Li XD, Wang L

Biomedical Optics Express, 2018; 9(9): 4481-4495

2017


Super-achromatic monolithic microprobe for ultrahigh-resolution endoscopic optical coherence tomography at 800 nm


Yuan W, Brown R, Mitzner W, Yarmus L, Li XD,

Nature Communications, 2017; 8(1): 1531

Robust and fast characterization of OCT-based optical attenuation using a novel frequency-domain algorithm for brain cancer detection


Yuan W, Kut C, Liang W, Li XD,

Scientific Reports, 2017; 7: 44909

Automatic and robust segmentation of endoscopic OCT images and optical staining


Zhang J*, Yuan W*, Liang WS, Yu S, Liang Y, Xu Z, Wei Y, Li XD

Biomedical Optics Express, 2017; 8(5): 2697-2708

Broadband rotary joint for high-speed ultrahigh-resolution endoscopic OCT imaging at 800 nm


Park HC, Mavadia-Shukla J, Yuan W, Alemohammad M, Li XD,

Optics Letters, 2017; 42(23): 4978-4981

2016


Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging


Yuan W, Mavadia-Shukla J, Xi J, Liang W, Yu X, Yu S, Li XD

Optics Letters, 2016; 41:250-253

Optical clearing for luminal organs imaging with ultrahigh-resolution optical coherence tomography


Liang Y*, Yuan W*, Mavadia-Shukla J, Li XD

Journal of Biomedical Optics, 2016; 21: 081211

Ultrahigh resolution endoscopic optical coherence tomography at 800 nm for imaging of bile duct


Yuan W, Mavadia-Shukla J, Ngamruengphong S, Gabrielson KL, Kalloo AN, Li XD

Gastrointestinal Endoscopy, 2016; 83:AB487

2015


Coherent mid-infrared supercontinuum generation with As2Se3 photonic crystal fiber and femtosecond Airy pulses


Yuan W

Laser Physics Letters, 2015; 12:125101

2014


Laser-assisted lateral optical fiber processing for selective infiltration


Zhang BM, Lai Y, Yuan W, Seah YP, Shum PP, Yu X, Wei H

Optics Express, 2014; 22:2675-2680

2013


High-Tg TOPAS microstructured polymer optical fiber for fiber Bragg grating strain sensing at 110 degrees


Markos C, Stefani A, Nielsen K, Rasmussen HK, Yuan W, Bang O

Optics Express, 2013; 21:4758-4765

2-10 μm mid-infrared supercontinuum generation in As2Se3 photonic crystal fiber


Yuan W

Optics Express, 2013; 21:4758-4765

2012


Tunable polymer fiber Bragg grating (FBG) inscription: fabrication of dual-FBG temperature compensated polymer optical fiber strain sensors


Yuan W, Stefani A, Bang O

Photonics Technology Letters, 2012; 24: 401-403

Nonlinear fiber-optic strain sensor based on four-wave mixing in microstructured optical fiber


Gu B, Yuan W, Frosz MH, Zhang AP, He S, Bang O

Optics Letters, 2012; 37:794-796

High sensitivity polymer optical fiber Bragg grating based accelerometer


Stefani A, Andresen S, Yuan W, Herholdt-Rasmussen N, Bang O

Photonics Technology Letters, 2012; 24:763-765

Dynamic characterization of polymer optical fibres


Stefani A, Andresen S, Yuan W, Bang O

IEEE Sensors Journal, 2012; 10:3047-3053

2011


Improved thermal and strain performance of annealed polymer optical fiber Bragg gratings


Yuan W, Stefani A, Bache M, Jacobsen T, Rose B, Herholdt-Rasmussen N, Nielsen FK, Andresen S, Sørensen OB, Hansen KS, Bang O

Optics Communications, 2011; 284:176-182

Optical fibre Bragg grating recorded in TOPAS cyclic olefin copolymer


Johnson IP, Yuan W, Stefani A, Nielsen K, Rasmussen HK, Khan L, Webb DJ, Kalli K, Bang O

Electronics Letters, 2011; 47:271 – 272

A reason to Bragg


Johnson IP, Yuan W, Stefani A, Nielsen K, Rasmussen HK, Khan L, Webb DJ, Kalli K, Bang O

Electronics Letters, 2011; 47:228

Narrow bandwidth 850nm fiber Bragg grating in few-mode polymer optical fibers


Stefani A, Yuan W, Markos C., Bang O

Photonics Technology Letters, 2011; 23:660-662

Label-free biosensing with high sensitivity in dual-core microstructured polymer optical fibers


Markos C, Yuan W, Vlachos K, Town GE, Bang O

Optics Express, 2011; 19:7790-7798

Optical fiber milled by focused ion beam and its application for Fabry-Pérot refractive index sensor


Yuan W, Wang F, Savenko A, Petersen DH, Bang O

Review of Scientific Instrument, 2011; 82: 076103-076105

Selective filling of photonic crystal fibers using focused ion beam milled microchannels


Wang F, Yuan W, Hansen O, Bang O

Optics Express, 2011; 19:17585-17590

Humidity insensitive TOPAS polymer fiber Bragg grating sensor


Yuan W, Khan L, Webb DJ, Kalli K, Rasmussen HK, Stefani A, Bang O

Optics Express, 2011; 19:19731-19739

Temperature compensated strain sensor based on cascaded Sagnac interferometers and all-solid birefringent hybrid photonic crystal fibers


Gu B, Yuan W, He S, Bang O

IEEE Sensors Journal, 2011; 99:1-6

2010


Microstructured optical fiber refractive index sensor


Town GE, Yuan W, McCosker R, Bang O

Optics Letters, 2010; 35:856-858

Refractive index sensing in an all-solid twin-core photonic bandgap fiber


Yuan W, Town GE, Bang O

IEEE Sensors Journal, 2010; 10:1192-1199

2009


Thermal tunability of photonic bandgaps in liquid crystal infiltrated microstructured polymer optical fibers


Yuan W, Wei L, Alkeskjold TT, Bjarklev AO, Bang O

Optics Express, 2009; 17:19356-19364

Surface-enhanced Raman scattering biosensor for DNA detection on nanoparticle island substrates


Yuan W, Ho HP, Lee R, Kong SK

Applied Optics, 2009; 48:4329-4337

Polarization-sensitive surface plasmon enhanced ellipsometry biosensor using the photoelastic modulation technique


Yuan W, Ho HP, Wu SY, Suen YK, Kong SK

Sensors and Actuators A: Physical, 2009; 151:23-28

2008


Real-time protein biosensor arrays based on surface plasmon resonance differential phase imaging


Wong CL, Ho HP, Suen YK, Kong SK, Chen QL, Yuan W, Wu SY

Biosensors and Bioelectronics, 2008; 24:606-612

2007


Two dimensional biosensor arrays based on SPR phase imaging


Wong CL, Ho HP, Yu TT, Suen YK, Chow W, Wu SY, Law WC, Yuan W, Li WJ, Kong SK, Lin CL

Applied Optics, 2007; 46:2325-2332

Surface plasmon resonance biosensor incorporated in a Michelson interferometer with enhanced sensitivity


Yuan W, Ho HP, Wong CL, Kong SK, Lin CL

IEEE Sensors Journal, 2007; 7:70-73

Sensitivity enhancement based on application of multi-pass interferometry in phase-sensitive surface plasmon resonance biosensor


Ho HP, Yuan W, Wong CL, Wu SY, Suen YK, Kong SK, Lin CL

Optics Communications, 2007; 275:491-496

Improving sensitivity limit of surface plasmon resonance biosensors by detecting mixed interference signals


Yuan W, Ho HP, Suen YK, Kong SK, Lin CL

Applied Optics, 2007; 46:8068-8073