3-Dimensional Microphysiological Tissue Models
development of organotypic culture models of neuromusculoskeletal tissues amenable to study of disease pathogenesis and the testing and screening of candidate therapeutic agents
Scientific Sharing by Prof. CHAN Hon-fai- Bioactive Glass-Loaded Microsphere as Oral Drug for IBD Treatment
New therapy for inflammatory bowel disease (IBD) is needed due to primary drug failure or loss of response to drugs for patients suffering from the disease. The recent findings from the collaborative work led [...]
Scientific Sharing by Prof. JIANG Yangzi’s Team- “Slow walk” Mimetic Tensile Loading Maintains Human Meniscus Tissue Resident Progenitor Cells Homeostasis In Photocrosslinked Gelatin Hydrogel
This research project is completed under the supervision of Prof. JIANG Yangzi and Prof. TUAN S. Rocky, and Dr. SUN Jing is the first author. It is worth noting that Dr. SUN Jing, who took part in [...]
Scientific Sharing by Prof. Elmer Ker, Prof. Rocky Tuan, Prof. Michelle Wang, Dr. Xu Zhang, Dr. Ke Li
This research project is completed under Prof. KER Dai Fei Elmer. It is worth noting that Dr. Ke Li, who took part in this project, was an iTERM/SBS Ph.D. student who graduated last year and is now [...]
Deciphering and Engineering Tissue Folding: A Mechanical Perspective
This research project is completed under Prof. Hon Fai CHAN. Tissue folding is a common phenomenon in a variety of organisms including human, and has been shown to serve important structural and functional roles. [...]
Efficient Fabrication of Monodisperse Hepatocyte Spheroids and Encapsulation in Hybrid Hydrogel with Controllable Extracellular Matrix Effect
This research project is completed under Prof. Hon Fai CHAN. Three-dimensional (3D) cultures, such as spheroid and organoid cultures, have gained increasing interest as 3D culture models. However, the understanding and control of extracellular [...]
Engineering Hydrogel for Biomedical Applications
Hepatocyte spheroids can contribute to liver research in various capacities. However, the technique of spheroid culture is far from optimal, as it is challenging to generate and maintain uniform-sized spheroids on a large scale. Moreover, [...]