Prof YUNG Shu-hang, Patrick, MH, JP |
Prof ONG Tim-yun, Michael |
Prof WONG Ronald Man Yeung |
Prof LING Ka-kin, Samuel |
Dr LAW Sheung-wai |
Dr WONG Wing-yee, Clara |
Dr HO Ki-wai, Kevin |
Dr LAM Tsz-ping |
Prof LEUNG Ping-chung, SBS, OBE, JP |
Prof CHAN Kai-ming, OBE, JP |
Prof LEUNG Kwok-sui |
Prof CHENG Chun-yiu, Jack |
Prof KUMTA Shekhar Madhukar |
Prof QIN Ling |
Prof LI Gang |
Prof WANG Huating |
Prof CHEUNG Wing-hoi, Louis |
Prof LUI Po-yee, Pauline |
Prof LEE Yuk-wai, Wayne |
Prof XU Jiankun, Jerry |
Prof ZHANG Ning |
Prof LIN Sien |
Prof CHUI Chun-sing, Elvis |
Prof TONG Wenxue |
Prof CHEN Xiaona |
|
|
CONTACT INFORMATION
Office : (852) 2471-6706
Email : waynelee@cuhk.edu.hk
ACADEMIC ENGAGEMENT
Postgraduate supervision:
MPhil/PhD in Orthopaedics & Traumatology
ORCID:
0000-0002-0486-360X
ResearcherID:
H-8298-2013 |
|
Professor LEE Yuk-wai, Wayne 李郁偉 |
BSc(Hons, HKBU), PhD(CUHK)
Assistant Professor of Orthopaedics and Traumatology
矯形外科及創傷學系助理教授
BIOGRAPHY
Professor Lee obtained his PhD in Pharmacology from The Chinese University of Hong Kong in 2009, then pursued postdoctoral training in the Department of Orthopaedics and Traumatology of CUHK. He has published over 90 publications in peer-reviewed international journals (Scopus H-index 30), and serves as reviewers of a number of international journals.
His research can be divided into two major areas of orthopaedic with important clinical relevance. The first line focuses on the development of GMP-grade cell therapy to treat osteoarthritis and other musculoskeletal problems. He is a registered authorized person for advanced therapy product in Hong Kong. His team also explore novel treatment strategies such as MSC secretome, miRNA and biomaterials with MSC tracking and controlled release properties. The second line is on the biological roles of osteocyte in adolescent idiopathic scoliosis and bone aging. His team has developed advanced research platforms for the study of osteocyte, and recently established a composite model composed of circulating microRNA and bone turnover marker to predict curve progression.
SPECIALISED RESEARCH AREAS
- Adolescent Idiopathic Scoliosis
- Clinical Application of Cell Therapy
- Musculoskeletal Aging
|
SELECTED PUBLICATION
1. |
Q. Li, R. Wang, Z. Zhang, H. Wang, X. Lu, J. Zhang, A. Kong, X.Y. Tian, H.F. Chan, A.C.K. Chung, J.C.Y. Cheng, Q. Jiang, W.Y. Lee*. Sirt3 mediates the benefits of exercise on bone in aged mice. Cell Death and Differentiation, accepted. (IF: 12.077) |
2. |
J. Sun, J.H.T. Lo, L. Fan, T.L. Yiu, A. Shakoor, G. Li, W.Y. Lee*, D. Sun*. High-efficiency quantitative control of mitochondrial transfer based on droplet microfluidics and its application on muscle regeneration. Science Advances. 2022;8(33):eabp9245. (IF: 14.972) |
3. |
B. Wang*, M. Pang, Y. Song, H. Wang, P. Qi, S. Bai, X. Lei, S. Wei, Z. Zong, S. Lin, X. Zhang, X. Cen, X. Wang, Y. Yang, Y. Li, Y. Wang, H. Xu, L. Huang, M. Tortorella, B. Cheng, W.Y. Lee*, D. Qin*, G. Li*. Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat-shock protein family. Bioengineering & Translational Medicine. 2022;e10354. (IF: 10.684) |
4. |
Y. Wang, M. Li, C.O. Chan, G. Yang, J.C.K. Lam, B.C.S. Law, T.P. Lam, A.L.H. Hung, J.C.Y. Cheng, D.K.W. Mok*, W.Y. Lee*. Biological effect of dysregulated LBX1 on adolescent idiopathic scoliosis through modulating muscle carbohydrate metabolism. The Spine Journal. 2022;22(9):1551-1565. (IF: 4.297) |
5. |
Q. Li, J.C.Y. Cheng, Q. Jiang, W.Y. Lee*. Role of sirtuins in bone biology: potential implications for novel therapeutic strategies for osteoporosis. Aging Cell, 2020;20(2):e13301. (IF: 11.005) |
6. |
J. Zhang, K.Y. Cheuk, L. Xu, Y. Wang, Z. Feng, T. Sit, K.L. Cheng, E. Nepotchatykh, T.P. Lam, Z. Liu, A.L.H. Hung, Z. Zhu, A. Moreau, J.C.Y. Cheng, Y. Qiu, W.Y. Lee*. A validated composite model to predict risk of curve progression in adolescent idiopathic scoliosis. EClinicalMedicine, 2020;18:100236. (IF: 17.033) |
7. |
S. Lin, L. Cui, G. Chen, J. Huang, Y. Yang, K. Zou, Y. Lai, X. Wang, L. Zou, T. Wu, J.C.Y. Cheng, G. Li, B. Wei, W.Y. Lee*. PLGA/β-TCP composite scaffold incorporating salvianolic acid B promotes bone fusion by angiogenesis and osteogenesis in a rat spinal fusion model. Biomaterials, 2019;196:109-121. (IF: 15.304) |
8. |
J. Zhang, H. Chen, R.K.K. Leung, K.W. Choy, T.P. Lam, B.K.W. Ng, Y. Qiu, J.Q. Feng, J.C.Y. Cheng, W.Y. Lee*. FASEB Journal, 2018;32(12):6537–6549. (IF: 5.834) |
9. |
W.Y. Lee*, T. Zhang, C.P. Lau, C.C. Wang, K.M. Chan, G. Li. Immortalized human fetal bone marrow-derived mesenchymal stromal cell expressing suicide gene for anti-tumor therapy in vitro and in vivo. Cytotherapy, 2013;15:1484-1497. (IF: 6.196) |
10. |
W.Y. Lee*, P.P. Lui, Y.F. Rui. Hypoxia-mediated efficient expansion of human tendon-derived stem cells in vitro. Tissue engineering. Part A, 2012;18(5-6):484-498. (IF: 4.080) |
|