O&T, CUHK

Academic Profile

Prof LI Gang

Prof WANG Huating

Prof CHEUNG Wing-hoi, Louis

Prof LUI Po-yee, Pauline

Prof LEE Yuk-wai, Wayne

Prof XU Jiankun, Jerry

Prof ZHANG Ning

Prof LIN Sien

Prof CHUI Chun-sing, Elvis

Prof TONG Wenxue

Prof CHEN Xiaona

CONTACT INFORMATION

Office : (852) 3505-2731

Email : gangli@cuhk.edu.hk

ACADEMIC ENGAGEMENT

Undergraduate teaching:
MBChB Programme
General Education Teaching

Postgraduate supervision:
PhD in Orthopaedics & Traumatology

ORCID: 0000-0002-3981-2239
ResearcherID: J-7830-2018

Professor LI Gang 李剛

MBBS(4 MMU, China), D. Phil(Oxon)

Professor of Orthopaedics and Traumatology
矯形外科及創傷學系教授

BIOGRAPHY

Gang Li is a full non-clinical professor in the Department of Orthopedics and Traumatology, The Chinese University of Hong Kong. He received MBBS at the Fourth Military Medical University, Xian, China (1991) and D. Phil. at the University of Oxford School of Medicine, England, UK (1998). Previously he was Lecturer, Senior Lecturer and Reader (1998-2009), at Department of Orthopaedic Surgery, School of Medicine, Queen's University, Belfast, UK. Prof Li holds valid PR China Medical Doctor Qualification Certificate and PR China Medical Practicing License (Surgery) and has honorary appointments in several orthopaedic surgery departments in PR China.

The focuses of Prof. Li’s research work are on biological mechanisms and novel clinical applications of distraction histogenesis; stem cell biology and cell therapy applications in musculoskeletal tissue engineering. He has published more than 290 peer-reviewed SCI articles with citations over 12,500 and H index 67 (Google scholar 05-2022; https://scholar.google.com/citations?hl=zh-CN&user=YIGsB6QAAAAJ&view); 16 book chapters and 3 books on tissue engineering, bone biology, distraction histogenesis and Ilizarov techniques. He is currently a honorary council member of Chinese Orthopaedic Research Society; Chinese ORS Representative to International Combined Orthopaedic Research Societies (ICORS); Member of International Committee, American Orthopaedic Research Society (ORS); Vice Chairman, Branch of Regenerative Biomaterials, Chinese Association of Materials; Member-at-Large (Global position), Tissue Engineering and Regenerative Medicine Society (TERMIS) Asia Pacific (AP); Co-Chairman of ILLRS and ASAMI China Branch. He is executive associate editor for Journal of Orthopaedic Translation (IF: 5.19); editor for Calcified Tissue International, Bone and Joint Research, Bone and Journal of Orthopaedic Research. Prof Li holds honorary or visiting Professorship at many prestigious universities such as Monash University, Australia; South-East University Medical School, China; The Airforce Medical University, China; Gong Dong Medical University and Jilin University Medical School, etc. His work received serval awards including 1st Class Award in Science Advances, Ministry of Science and Technology, PR China (2020); 1st Class Research Award in Science and Technology, Ministry of Education, China (2015); 2nd Class Award in Medical Science and Technology, China Medical Association (2018). He is elected as fellow of International Combined Orthopaedic Research Societies (FIORS) in 2016 and fellow of American Orthopaedic Research Society (FORS) in 2020.

EXPERTISE

Stem Cell Therapy in Musculoskeletal Tissue Engineering
Limb Deformity Correction and Reconstruction Mechanisms
Novel Clinical Applications of Tibial Cortex Transverse Transport for Avascular Diseases
Cranial Bone Transport for Neurological Function Recovery in Stroke and Trauma Brain Injury Conditions

SPECIALISED RESEARCH AREAS

Distraction Histogenesis Mechanisms and Novel Clinical Applications
Stem Cell Biology and Cellular Therapies in Musculoskeletal Tissues
Biomaterials and Biophysical Stimuli for Musculoskeletal Tissue Engineering

SELECTED PUBLICATION

1.	Bai SS#, Lu X#, Xuan Lu, Pan Q, Wang B, U KP, Yang YK, Wang HX, Lin SE, Feng L, Wang Y, Li YC, Lin WP, Wang YJ, Zhang XT, Li Y, Li LL, Yang ZM, Wang M, Lee WYW, Jiang XH, Li G. Cranial bone transport promotes angiogenesis, neurogenesis and modulates meningeal lymphatic function in MCAO rats. Stroke 2022 Apr; 53(4):1373-1385 (DOI: 10.1161/STROKEAHA.121.037912) [IF: 7.914].*
2.	Wang B#, Pang MR#, Song YC, Wang HX, Pan Q, Bai SS, Lei XX, Wei SK, Zhang XT, Wang X, Yang YK, Li Y, Wang Y, Xu HJ, Hang L, Cheng B, Lee YK, Qin DJ, Li G. Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat-shock protein family. Bioengineering & Translational Medicine, 2022, in press [IF: 10.71]
3.	Deng YR, Li Rui, Wang HX, Yang BG, Shi P, Zhang Y, Yang Q, Li G, Bian LM. Biomaterial-mediated presentation of Jagged-1 mimetic ligand enhances cellular activation of Notch signaling and bone regeneration. ACS Nano, 2022, in press. 10.1021/acsnano.1c08728. [IF: 15.881]
4.	Deng YR#, Zhang XT, Li R, Li Z, Yang BG, Shi P, Zhang HL, Wang CM, Weng CY, Li G, Bian LM. Biomaterial-mediated presentation of wnt5a mimetic ligands enhances chondrogenesis and metabolism of stem cells by activating non-canonical Wnt signaling. Biomaterials, 2021 Dec 9; 281:121316. https://doi.org/10.1016/j.biomaterials.2021.121316 [IF: 12.479]
5.	Li Z, Wang HX, Zhang KY, Yang BG, Xie X, Yang ZM, Kong LC, Shi P, Zhang Y, Ho YP, Zhang ZY , Li G, Bian LM. Bisphosphonate-based hydrogel mediates biomimetic negative feedback regulation of osteoclastic activity to promote bone regeneration. Bioactive Materials, 2021; 13:9-22. https://doi.org/10.1016/j.bioactmat.2021.11.004 [IF: 14.593]*
6.	Shakoor A#, Wang B, Fan L, Kong L, Gao W, Sun J, Man K, Li G, Sun D. Automated optical tweezers manipulation to transfer mitochondria from fetal to adult MSCs to improve anti-aging gene expressions. Small, 2021; 2103086. https://doi.org/10.1002/smll.202103086 [IF:13.281]
7.	Li Y#, Xu JK, Mi J, He X, Pan Q, Zheng LZ, Zu HY, Chen ZY, Dai BY, Li X, Pang QQ, Zou L, Zhou LB, Huang L, Tong WX, Li G, Qin L. Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis. Biomaterials, 2021; 275: 120984. https://doi.org/10.1016/j.biomaterials.2021.120984. [IF: 12.479]
8.	Yuan W, Wang H, Fang C, Yang Y, Xia X, Yang B, Lin Y, Li G, Bian L. Microscopic local stiffening in a supramolecular hydrogel network expedites stem cell mechanosensing in 3D and bone regeneration. Materials Horizons, 2021; 8: 1722-1734. https://doi.org/10.1039/D1MH00244A [IF: 13.266]
9.	Feng L, Yang ZM, Li YC, Wang HX, Lo JHT, Zhang XT, Li G. Linc-ROR promotes mesenchymal stem cells chondrogenesis and cartilage formation via regulating SOX9 expression. Osteoarthritis Cartilage, 2021 Apr; 29(4):568-578. [IF: 6.576]*
10.	Xu J, Feng Q, Lin S, Yuan W, Li R, Li J, Wei K, Chen X, Zhang K, Yang Y, Wu T, Wang B, Zhu M, Guo R, Li G, Bian L. Injectable stem cell-laden supramolecular hydrogels enhance in situ osteochondral regeneration via the sustained co-delivery of hydrophilic and hydrophobic chondrogenic molecules. Biomaterials. 2019 Jul; 210:51-61. [IF: 12.479]