Research
WANG Chi Chiu
Name : WANG Chi Chiu 黃志超
Home Department :  Obstetrics & Gynaecology
Email : ccwang@cuhk.edu.hk
Office Phone Number : (852) 3505 3099
Office Fax Number :  (852) 2636 0008
Address : Room 505, Li Ka Shing Medical Sciences Building,
Prince of Wales Hospital, Shatin, New Territoies, Hong Kong
Website :
www.obg.cuhk.edu.hk/wang-chi-chiu-ronald/


Biography:

i) Academic & Professional Qualifications:

MBBS (Hons), PhD (Surgical Sciences), PhD (Genetics), DipTCM (Chinese Medicine), DipTCM (Acupuncture), FRSC (UK), SAB (US)

ii) Current Academic Positions:

Professor, Department of Obstetrics & Gynaecology, CUHK

Division Head, Division of Obstetrics & Gynaecology, CUHK

Associate Member, School of Biomedical Science, CUHK

Deputy Director, Prenatal Genetics Diagnosis Centre, CUHK

 

Specialised Research Area(s):

Reproductive and Developmental Biology

 

Selected Publications:

1. Wu, X.K., Stener-Victorin, E., Kuang, H.K., Ma, H.L., Gao, J.S., Xie, L.Z., Hou, L.H., Hu, Z.X., Shai, X.G., Ge, J., Zhang, J.F., Xue, H.Y., Xu, Z.F., Liang, R.N., Ma, H.X., Yang, H.W., Li, W.L., Huang, D.M., Sun, Y., Hao, C.F., Du, S.M., Yang, Z.W., Wang, X., Yan, Y., Chen, X.H., Fu, P., Ding, C.F., Gao, Y.Q., Zhou, Z.M., Wang, C.C., Wu, T.X., Liu, J.P., Ng, E.H., Legro, R.S., Zhang, H.P. & PCOSAct Study Group. (2017). Effect of Acupuncture and Clomiphene in Chinese Women With Polycystic Ovary Syndrome: a randomized clinical trial. JAMA, 317(24):2502-14.

 2. Lui, N.C., Tam, W.Y., Gao, C.J., Huang, J.D., Wang, C.C., Jiang, L.W., Yung, W.H., & Kwan, K.M. (2017). Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin. Nature Communications, 8:15079.

3. Zhou, L., Sun, K., Zhao, Y., Zhang, S.Y., Wang, X.C., Li, Y.Y., Lu, L.N., Chen, X.N., Chen, F.Y., Bao, X.C., Zhu, X.H., Wang, L.J., Tang, L.Y., Esteban, M.A., Wang, C.C., Jauch, R., Sun, H., & Wang, H.T. (2015) Linc-YY1 promotes skeletal myoblast differentiation and muscle regeneration through interacting with YY1. Nature Communications, 6:e10026.

4. Brutsch, S.H., Wang, C.C., Li, L., Stender, H., Neziroglu, N., Richter, C., Kuhn, H., & Borchert, A. (2015) Expression of inactive glutathione peroxidase 4 leads to embryonic lethality and inactivation of the Alox15 gene does not rescue such knock-in mice. Antioxidants & Redox Signaling, 22(4):281-93.

5. Li, L., Dou, L.X., Neilson, J.P., Leung, P.C., & Wang, C.C. (2012). Adverse outcomes of Chinese medicines used for threatened miscarriage: a systematic review and meta-analysis. Human Reproduction Update, 18(5):504-524.

6. Lee, L.M., Leung, C.Y., Tang, W.W., Choi, H.L., Leung, Y.C., McCaffery, P.J., Wang, C.C., Woolf, A.S., & Shum, A.S. (2012) A paradoxical teratogenic mechanism for retinoic acid. Proceedings of the National Academy of Sciences of the United States of America, 109:13668-73.

7. Wang, C.C., Billett, E., Borchert, A., Kuhn, H., & Ufer, C. (2012) Monoamine oxidases in development. Cellular and Molecular Life Sciences, 70(4):599-630.

8. Ufer, C., Wang, C.C., Borchert, A., Heydeck, D., & Kuhn, H. (2010) Redox control in mammalian embryo development. Antioxidants & Redox Signaling, 13(6):833-75.

9. Kai, Y., Wang, C.C., Kishigami, S., Kazuki, Y., Abe, S., Takiguchi, M., Wakayama, T., Shirayoshi, Y., Inoue, T., Ito, H., & Oshimura, M. (2009) Enhanced apoptosis during early neuronal differentiation in mouse ES cells with autosomal imbalance. Cell Research19(2): 247-258.

10. Ufer, C., Wang, C.C., Fahling, M., Schiebel, H., Thiele, B.J., Billett, E.E., Kuhn, H., & Borchert, A. (2008) Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence binding factor 1 is essential for embryonic brain development. Genes & Development, 22:1835-50.