Research
FUNG, Erik

Name : Erik Fung 馮以文
Title :
Assistant Professor (Clinical)
Home Department :  Medicine and Therapeutics
Email : e.fung@cuhk.edu.hk
Phone Number: (852) 3505 3140
Website:  https://www.mect.cuhk.edu.hk/LHFCR/
Profile Website:  https://www.mect.cuhk.edu.hk/people/erikfung.html

Biography:

Dr Erik Fung is an academic cardiologist and physician-scientist in the Department of Medicine and Therapeutics, The Chinese University of Hong Kong. He is a medical graduate of CUHK and has had predoctoral, PhD and postdoctoral research training at Harvard Medical School, University of Cambridge, Dartmouth College, and Imperial College London. During his research training at Cambridge, he was a Prince Philip Graduate Exhibition scholar and JDRF Postdoctoral Fellow. After cardiology training at Dartmouth, he further sub-specialised in advanced heart failure, ventricular assist device and transplant cardiology at University of Southern California. Dr Fung's research team is focused on heart failure, circulatory disorders, and inflammation.

 

Specialised Research Area(s):

Heart failure; Circulatory disorders; Inflammation and thrombosis; Animal models of cardiomyopathy and mechanical circulatory support.

 

Selected Publications:

1. Lee-Ling Lim, Eric SH Lau, Erik Fung, Heung-Man Lee, Ronald CW Ma, Claudia HT Tam, Willy KK Kong, Alex SW Ng, Elaine Chow, Andrew OY Luk, Alicia Jenkins, Juliana CN Chan, Alice PS Kong. Independent association of serum branched-chain amino acids with incident heart failure in type 2 diabetes: the Hong Kong Diabetes Register. Diabetes/Metabolism Research and Reviews 2020;36:e3253. doi: 10.1002/dmrr.3253. (IF 4.758)

2. Erik Fung*, Leong Ting Lui, Finn Gustafsson, Forrest CF Yau, Jason CS Leung, Petri Wiklund, Marjo-Riitta Järvelin, Peter S Macdonald, Jean Woo. Predicting 10-year mortality in older adults using VO2max, oxygen uptake efficiency slope and frailty class. European Journal of Preventive Cardiology 2020 Mar 30. doi: 10.1177/2047487320914435. (IF 7.804)

3. Xiaobo Yang, Jean Woo, Leong Ting Lui, Qi Li, King Fai Cheng, Yiting Fan, Forrest Yau, Alex PW Lee, Jenny SW Lee, Erik Fung*. Cardiac manifestations of sarcopenia. Journal of Nutrition Health and Aging 2020;24:478–484. doi: 10.1007/s12603-020-1358-8. (IF 4.075)

4. Jun Ni, Fuye Yang, Xiao-Ru Huang, Jinxiu Meng, Jiaoyi Chen, Michael Bader, Josef M Penninger, Erik Fung, Xue-Qing Yu, Hui Yao Lan. Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy. Journal of Cellular and Molecular Medicine 2020 Sep 24. doi: 10.1111/jcmm.15914.(IF 5.310)

5. Chandu Sadasivan, Josie TY Chow, Bun Sheng, David Chan, Yiting Fan, Paul CL Choi, Jeffrey KT Wong, Mabel MP Tong, Tsz-Ngai Chan, Erik Fung, Kevin KH Kam, Joseph YS Chan, Wai K Chi, David I Paterson, Manohara Senaratne, Neil Brass, Gavin Y Oudit, Alex PW Lee. Screening for Fabry disease in patients with unexplained hypertrophic cardiomyopathy. PLoS ONE 2020;15:e0239675. doi: 10.1371/journal.pone.0239675. (IF 3.240)

6. Ganesan Karthikeyan, Erik Fung, Roger S-Y Foo. An alternative hypothesis to explain disease progression in rheumatic heart disease. Circulation 2020;142:2091-2094. doi: 10.1161/CIRCULATIONAHA.120.050966. (IF 23.603)

7. Sek-Ying Chair, Ho Yu Cheng, Kai Chow Choi, Elaine KC Siow, Xi Cao, Erik Fung*. Influenza-Associated Hospitalizations and Risk of Subsequent Heart Failure Hospital Admissions: A 20-Year Territorywide Registry Study in Hong Kong, China. American Journal of Epidemiology 2021;190:779-785. doi: 10.1093/aje/kwaa263. (IF 4.526)

8. Yiting Fan, Tsz-Ngai Chan, Josie TY Chow, Kevin KH Kam, Wai-Kin Chi, Joseph YS Chan, Erik Fung, Mabel MB Tong, Jeffery KT Wong, Paul CL Choi, David KH Chan, Bun Sheng, Alex PW Lee. High prevalence of late-onset Fabry cardiomyopathy in a Cohort of 499 non-selective patients with left ventricular hypertrophy: The Asian Fabry Cardiomyopathy High-Risk Screening Study (FAME). Journal of Clinical Medicine 2021;10:2160. doi: 10.3390/jcm10102160. (IF 4.241)

9. Polakit Teekakirikul, Wenjuan Zhu, George C Gabriel, Cullen B Young, Kylia Williams, Lisa J Martin, Jennifer C Hill, Tara Richards, Marie Billaud, Julie A Phillippi, Jianbin Wang, Yijen Wu, Tuantuan Tan, William Devine, Jiuann-huey Lin, Abha S Bais, Jonathan Klonowski, Anne Moreau de Bellaing, Ankur Saini, Michael X Wang, Leonid Emerel, Nathan Salamacha, Samuel K Wyman, Carrie Lee, Hung Sing Li, Anastasia Miron, Jingyu Zhang, Jianhua Xing, Dennis M McNamara, Erik Fung, Paul Kirshbom, William Mahle, Lazaros K Kochilas, Yihua He, Vidu Garg, Peter White, Kim L McBride, D Woodrow Benson, Thomas G Gleason, Seema Mital, Cecilia W Lo. Common deletion variants causing protocadherin-a deficiency contribute to the genetic etiology of bicuspid aortic valve and left-sided congenital heart disease. Human Genetics and Genomics Advances 2021;2:100037. doi: 10.1016/j.xhgg.2021.100037.

10. Erik Fung*, Ho Yu Cheng, Kai Choi Chow, David SC Hui, Cheng Yang, Sek Ying Chair. Differential Risks For Heart Failure Hospitalization Following Severe Respiratory Infections By Common Pathogens. European Journal of Preventive Cardiology 2021 (accepted 6 July 2021). (IF 7.804)

11. Xiaowei Ojanen, Runtan Cheng, Timo Törmäkangas, Noa Rappaport, Tomasz Wilmanski, Na Wu, Erik Fung, Rozenn Nedelec, Sylvain Sebert, Dimitris Vlachopoulos, Wei Yan, Nathan D Price, Sulin Cheng, Petri Wiklund. Towards early risk biomarkers: serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood. EBioMedicine 2021;72:103611.

12. Erik Fung, Leong-Ting Lui, Lei Huang, King Fai Cheng, Gloria HW Lau, Yi Ting Chung, Behzad Nasiri Ahmadabadi, Suyi Xie, Jenny SW Lee, Elsie Hui, Wing Yee So, Joseph JY Sung, Irwin King, William B Goggins, Queenie Chan, Marjo-Riitta Järvelin, Ronald CW Ma, Elaine Chow, Timothy Kwok. Characterising frailty, metrics of continuous glucose monitoring, and mortality hazards in older adults with type 2 diabetes on insulin therapy (HARE): a prospective, observational cohort study. The Lancet Healthy Longevity 2021;2:e724-e735.