Professor LEE, Hung Kay(李鴻基教授)

Associate Professorppl---lhk

location    Room 261 Science Centre

Phone No.    (852) 3943 6331

Email    hklee@cuhk.edu.hk

0000-0002-2052-4069

 

 

 

 

 

 

 

 

Education

1995 Ph.D. The Chinese University of Hong Kong
1990 B.Sc. The Chinese University of Hong Kong

 

Position

2020–Present Programme Director
MSc Programme in Accreditation Chemistry, The Chinese University of Hong Kong
2016–Present Associate College Head and Dean of General Education
United College, The Chinese University of Hong Kong
2012-2016 Associate Dean of General Education
United College, The Chinese University of Hong Kong
2010–Present Associate Director
Environmental Science Programme, The Chinese University of Hong Kong
2003–Present Associate Professor
Department of Chemistry, The Chinese University of Hong Kong
1997-2003 Assistant Professor
Department of Chemistry, The Chinese University of Hong Kong
1995-1997 Postdoctoral Scholar
California Institute of Technology

 

Research Interests

1. Synthesis, structural characterization, and reactivity studies of amidometal complexes.
2. Design of structural and functional mimics to the active sites of various metalloproteins.

 

Honours and Awards

Science Faculty Exemplary Teaching Awards 2003, 2015 and 2019

 

Professional Activities

2015–Present Honorary Secretary
The Royal Society of Chemistry (Hong Kong Section)
2008–Present Vice President
The Hong Kong Chemical Society

 

Representative Publications

1. Tze-Hei. Choi, Wing-Por. Leung, Hung Kay Lee and Yuk-Chi Chan:
“Metalation of 2-quinolyl-linked (boranophosphinoyl)methane. Alkali Metal, Alkaline Earth Metal and Ytterbium(II) Complexes of Monoanionic [CH(iPr2P–BH3)(C9H6N-2)]– Ligand”
Eur. J. Inorg. Chem., accepted for publication.
2. Cheuk Kit Ngai, Sik Lok Lam, Hung Kay Lee, and Pei Guo:
“A Purine and a Backbone Discontinuous Site Alter the Structure and Thermal Stability of DNA Minidumbbells Containing Two Pentaloops”,
FEBS Letters, 2022, 596, 826−840.
3. Ho Yin Yu, Hung Kay Lee, and Kin Shing Chan:
“Acylation of Rhodium(III) Porphyrin Complexes with Carboxylic Acids: Scope and Mechanism”,
Organometallics, 2021, 40, 3733−3741.
4. Liqi Wan, Sik Lok Lam, Hung Kay Lee, and Pei Guo:
“Effects of Adenine Methylation on the Structure and Thermodynamic Stability of a DNA Minidumbbell”,
Int. J. Mol. Sci., 2021, 22, 3633−3647.
5. Liqi Wan, Jie Yi, Sik Lok Lam, Hung Kay Lee, and Pei Guo:
“5‐Methylcytosine Substantially Enhances the Thermal Stability of DNA Minidumbbells”,
Chem. Eur. J., 2021, 27, 6740−6747.
6. Liqi Wan, Sik Lok Lam, Hung Kay Lee, and Pei Guo:
“Rational Design of a Reversible Mg2+/EDTA-controlled Molecular Switch Based on a DNA Minidumbbell”,
Chem. Commun., 2020, 56, 10127−10130.
7. Cheuk Kit Ngai, Sik Lok Lam, Hung Kay Lee, and Pei Guo:
“High-Resolution Structures of DNA Minidumbbells Comprising Type II Tetraloops with a Purine Minor Groove Residue”,
J. Phys. Chem. B, 2020, 124, 5131−5138.
8. George Fai Wong, Lai Fong Yeung, Ho Yin Tsoi, Hoi-Shan Chan, Ming-Hsi Chiang and Hung Kay Lee:
“A Mononuclear Iron(II) Bis(guanidinate) Complex: Synthesis, Structure, and Reactivity”,
Eur. J. Inorg. Chem., 2019, 98–109.
9. S. Yao, D. Y. S. Tam, P. S. Cheung, C.-K. Lam, P. Guo, S. L. Lam and H. K. Lee:
“Cobalt(II) Amido Complexes Derived from a Monodentate Arylamido Ligand Featuring a Highly Electron-withdrawing C6F5 Substituent”,
Dalton Trans., Vol. 44, pp. 17950–17959 (2015).
10. K. W. Ku, C. W. Au, H.-S. Chan and H. K. Lee:
“Divalent Europium and Ytterbium Complexes Supported by a Bulky 2-Pyridyl Amido Ligand: Synthesis, Structure and Reactivity Studies”
Dalton Trans. Vol. 42, pp. 2841–2852 (2013).
11. S. Yao, H.-S. Chan, C.-K. Lam and H. K. Lee:
“Synthesis, Structure and Reaction Chemistry of Samarium(II), Europium(II) and Ytterbium(II) Complexes of the Unsymmetrical Benzamidinate Ligand [PhC(NSiMe3)(NC6H3Pri2–2,6)]–”
Inorg. Chem., Vol. 48, pp. 9936–9946 (2009).
12. H. Y. Au-Yeung, C. H. Lam, C.-K. Lam, W.-Y. Wong and H. K. Lee:
“Unusual Iron(II) and Cobalt(II) Complexes Derived from Monodentate Arylamido Ligands”
Inorg. Chem., Vol. 46, pp. 7695–7697 (2007).
13. S. V. Pavlova, H. L. To, E. S. H. Chan, H.-W. Li, T. C. W. Mak, H. K. Lee and S. I. Chan:
“Synthesis, Structure and Dioxygen Reactivity of a Bis(μ–iodo)dicopper(I) Complex Supported by the [N–(3,5–di–tert–butyl–2–hydroxybenzyl)–N,N–di–(2–pyridylmethyl)]amine Ligand”,
Dalton Trans., pp.2232–2242 (2006).
14. H. K. Lee, T. S. Lam, C.-K. Lam, H.-W. Li and S. M. Fung:
“Synthesis and Structural Characterisation of Divalent Transition Metal Complexes Containing an Unsymmetrical Benzamidinate Ligand”,
New J. Chem., Vol. 27, pp. 1310–1318 (2003).
15. S. C. F. Kui, H.-W. Li and H. K. Lee:
“Cerium(III) and Neodymium(III) Amides Derived from a Chelating 2–Pyridyl Amido Ligand”,
Inorg. Chem., Vol. 42, pp. 2824–2826 (2003).
16. Y.-L. Wong, D. K. P. Ng and H. K. Lee:
“New Chloro, μ-oxo, and Alkyl Derivatives of Dioxomolybdenum(VI) and –Tungsten(VI) Complexes Chelated with N2O Tridentate Ligands: Synthesis and Catalyitc Activties toward Olefin Epoxidation”,
Inorg. Chem ., Vol. 41, pp. 5276-5285 (2002).
17. X.-M. Zhang, M.-L. Tong, M.-L. Gong, H. K. Lee, L. Luo, K. F. Li, Y.-X. Tong and X.-M. Chen:
“Syntheses, Crystal Structures, and Physical Properties of Dinuclear Copper(I) and Tetranuclear Mixed-valence Copper(I, II) Complexes with Hydroxylated Bipyridyl-like Ligands”,
Chem. Eur. J. , Vol. 8 (14), pp. 3187-3194 (2002).
18. Q.-M. Wang, H. K. Lee and T. C. W. Mak:
“A Mixed-valent Silver(I, II) Complex Containing a Self-assembled Silver(I) Cluster Dimer with Encapsulated Acetylide Dianion”,
New J. Chem. , Vol. 26, pp. 513-515 (2002).
19. S.-L. Zheng, M.-L. Tong, S.-D. Tan, Y. Wang, J.-X. Shi, Y.-X. Tong, H. K. Lee and X.-M. Chen:
“Syntheses, Structures, and Properties of Three Novel Coordination Polymers of Silver(I) Aromatic Carboxylates with Hexamethylenetetramine Exhibiting Unique Metal-π Interaction”,
Organometallics , Vol. 20, 5319-5325 (2001).
20. H. K. Lee, C. H. Lam, S.-L. Li, Z.-Y. Zhang and T. C. W. Mak:
“Low-Valent Chemistry of Cobalt Amide. Synthesis and Structural Characterization of Cobalt(II) Amido, Aryloxide, and Thiolate Compounds”,
Inorg. Chem. , Vol. 40, pp. 4691-4695 (2001).
21. X.-M. Zhang, M.-L. Tong, H. K. Lee and X.-M. Chen:
“The First Noncluster Vanadium(IV) Coordination Polymers: Solvothermal Syntheses, Crystal Structure, and Ion Exchange”,
Journal of Solide State Chemistry , Vol. 160, pp. 118-122 (2001).
22. H. K. Lee, Y.-L. Wong, Z.-Y. Zhou, Z.-Y. Zhang, D. K. P. Ng and T. C. W. Mak:
“Synthesis and Structures of Dioxo-Mo(VI) and –W(VI) Amides”,
J. Chem. Soc., Dalton Trans. , pp. 539-544 (2000).
23. A. R. Waldeck, M. H. B. Stowell, H. K. Lee , S.-C. Hung, M. Matsson, L. Hederstedt, B. A. C. Ackrell and S.I. Chan:
“Electron Paramagnetic Resonance Studies of Succinate:Ubiquinone Oxidoreductase from paracoccus denitrificans : I. Evidence for a Magnetic Interaction between the 3Fe-4S Cluster and Cytochrome “,
J. Biol. Chem. , Vol. 272, pp. 19373-19382 (1997).
24. S. M. Musser, M. H. B. Stowell, H. K. Lee, J. N. Rumbley, S. I. Chan:
“Uncompetitive Substrate Inhibition and Noncompetitive Inhibition by 5-n-Undecyl-6-hydroxy-4,7-dioxobenzothiazole (UHDBT) and 2-n-Nonyl-4-hydroxyquinoline-N-oxide (NQNO) is Observed for the Cytochrome bo3 Complex: Implications for a Q(H2)-loop Proton Translocation Mechanism”,
Biochemistry , Vol. 36, pp. 894-902 (1997).
25. W.-P. Leung, H. K. Lee, L.-H. Weng, Z.-Y. Zhou, T. C. W. Mak:
“Synthesis and Structural Characterisation of Mono- and Bi-nuclear Cobalt(II) Alkyls”,
J. Chem. Soc., Dalton Trans. , pp. 779-783 (1997).
26. W.-P. Leung, H. K. Lee, L.-H. Weng, B.-S. Luo, Z.-Y. Zhou, T. C. W. Mak:
“Synthesis and Structures of Iron(II) Alkyl and Thiolate Compounds Containing Sterically Hindered -Functionalized Alkyl Ligands”,
Organometallics , Vol. 15, pp. 1785-1792 (1996).

Books Published

1. W.-K. Li, H. K. Lee, D. K. P. Ng, Y.-S. Cheung, K. K. W. Mak and T. C. W. Mak, Problems in Structural Inorganic Chemistry, 2nd edition, Oxford University Press, 2019.
2. 李伟基,张羽伸,李奇,李鸿基,吴基培,麦建华,麦松威,无机结构化学习题(第2版),北京大学出版社,2019。

 

Major Research Grants

2020 General Research Fund, The Research Grants Council
2017 General Research Fund, The Research Grants Council
2015 General Research Fund, The Research Grants Council
2011 General Research Fund, The Research Grants Council
2007 Earmarked Research Grant, The Research Grants Council
2005 Earmarked Research Grant, The Research Grants Council