Professor WONG Kwok Chu George    
黃國柱

Professor
MB ChB (CUHK), MD (CUHK), FRCSEd (SN), FCSHK, FHKAM (Surgery)

Neurosurgery
(852) 3505 2624
georgewongadd this for spam@add this for spamsurgery.cuhk.edu.hk
L-4344-2016

Biography

Professor WONG Kwok Chu George is a specialist in Neurosurgery and credentialled on Endovascular Neurointerventional Procedures. He is Professor in Division of Neurosurgery, Department of Surgery, Faculty of Medicine of the Chinese University of Hong Kong, and Consultant (Honorary) of the Hospital Authority. Clinically, he is devoted to the service development for patients with subarachnoid hemorrhage, cerebral aneurysms, cerebral arteriovenous malformations, stroke, and traumatic brain injury. He has received numerous research awards and has published more than 200 papers in peer reviewed journals including Stroke, Journal of Neurology Neurosurgery and Psychiatry, Neurosurgery, and Journal of Neurosurgery. He is passionate in undergraduate and postgraduate medical education and chairs numerous workshops and courses for professional bodies. He serves key positions in a number of international and local professional bodies including European Stroke Organization, Asian Australasian Federation of Interventional and Therapeutic Neuroradiology, College of Surgeons of Hong Kong, Hong Kong Academy of Medicine, Hong Kong Society of Simulation in Healthcare, and Hong Kong Society of Interventional and Therapeutic Neuroradiology. He is the elected Congress President of the 15th AAFITN Biennial Congress. He has also completed the LLM(Arb&DR)(HKU) degree and is a Fellow member of the Chartered Institute of Arbitrators (FCIArb).

Research Interests

• Subarachnoid Haemorrhage
• Intracranial Aneurysm
• Brain Tumour
• Brain Injury Outcome Research
• Translational Stroke Research

Additional Information

Specialization:

• Neuro-endovascular intervention
• Neurosurgery

Award and Honour:

• GB Ong Travelling Fellowship (2007)
• Royal College of Surgeons of Edinburgh Syme Medal (2011)
• State Scientific and Technological Progress Award Second-class Award (2011)
• World Federation of Neurological Surgeons Young Neurosurgeon Award (2013)
• American College of Surgeons Centennial Scholar (2013)
• American College of Surgeons Elias Hanna Scholar (2013)
• Sir Robert Black Trust Fund Scholar (2013)
• Harvard MGH Athinoula A. Martinos Center for Biomedical Imaging fMRI Visiting Fellowship (2013)
• Chinese National Medical Association Science and Technology Award (2014)
• Boston Center for Medical Simulation Scholar (2015)
• American Heart Association Paul Dudley White International Scholar (2019)
• Fellow of the American College of Surgeons (2013)
• Fellow of the American Heart Association (2019)
• Fellow of the European Stroke Organization (2020)

Others:

1. Honorary Appointment:
   
   • Consultant (Honorary), NTEC, Hospital Authority
2. Editorship:
   
   • Neurointervention (Korean Society of Interventional Neuroradiology)
   • Journal of Japanese Medical Association
   • Frontiers in Surgery (Neurosurgery)
3. Professional Service:
   
   • Deputy Director of the Hong Kong Jockey Club Innovative Learning Centre for Medicine
   • Chairman, Education Subcommittee of the HKJC Innovative Learning Centre for Medicine, Workplace Based Assessment Course, OSCE Workshop and Course
   • Faculty members of CSEC, DSSI, LOL Courses of the HKJC Innovative Learning Centre for Medicine
   • Chairmen, Fellow Education Subcommittee, Procedural Sedation Course, Workplace Based Assessment Working Group, & Simulation Education Working Group, the College of Surgeons of Hong Kong
   • Council member of the College of Surgeons of Hong Kong
   • Members, Professionalism and Ethics Committee & Task Forces on Law for Healthcare Practitioners, Disclosure Apology Alternative Dispute Resolution, eHKAM, Hong Kong Academy of Medicine
   • Chairperson, Audit Programme of the COC(Neurosurgery) and Hospital Authority
   • Council member of the Asian Australasian Federation of Interventional and Therapeutic Neuroradiology
   • Steering committee member (Unruptured Cerebral Aneurysms and Subarachnoid Hemorrhage) of US National Library of Medicine and National Institute of Neurological Disorders and Stroke Common Data Elements
   • President of the Hong Kong Society of Simulation in Healthcare (2022-2023)
   • Vice President of the Hong Kong Society of Interventional and Therapeutic Neuroradiology (2022-2024)
   • Certified Healthcare Simulation Educator (CHSE), Society of Simulation in Healthcare
   • Fellow of the International Society for Quality in Healthcare
   • Fellow member of the Chartered Institute of Arbitrators (FCIArb)
   • Simulation Education Committee member of the European Stroke Organization
   • Congress President of the 15th Asian Australasian Federation of Interventional and Therapeutic Neuroradiology Biennial Congress (2023)
4. Academic Engagement:
   
   • Module coordinator of Neurosurgery CUHK MB ChB program
   • Undergraduate programs
   • Taught master programs
   • Research postgraduate supervision (MPhil, PhD)

Selected Publications

1. Chen J, Sun L, Lyu H, Zheng Z, Lai H, Wang Y, Luo Y, Lu G, Chan WY, Guan S, Zhang Y, Chen X, Li Z, Ko H, Wong KCG*. Single-cell analysis of microglial transcriptomic diversity in subarachnoid haemorrhage. Clin Transl Med. 2022 Apr;12(4):e783. doi: 10.1002/ctm2.783.
2. Yan J, Chen J, Chen J, Yan W, Ding Q, Yan K, Du J, Lam CP, Wong GKC, Cheng SS. A Continuum Robotic Cannula with Tip Following Capability and Distal Dexterity for Intracerebral Hemorrhage Evacuation. IEEE Trans Biomed Eng. 2022 Sep;69(9):2958-2969. doi: 10.1109/TBME.2022.3158539.
3. Chan HSC, Ng HK, Chan AK, Cheng SH, Chow C, Wong N, Wong GKC*. Establishment and characterization of meningioma patient-derived organoid. J Clin Neurosci. 2021 Dec;94:192-199. doi: 10.1016/j.jocn.2021.10.035.
4. Zheng ZV, Chen J, Lyu H, Lam SYE, Lu G, Chan WY, Wong GKC*. Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage. Stroke Vasc Neurol. 2022 Feb;7(1):62-70. doi: 10.1136/svn-2021-001028.
5. Zheng ZY, Lu G, Xiong ZQ, Leung CK, Su XW, Li T, Poon WS, Chan WY, Wong GKC*. Integrated analysis of gait parameters and gene expression profiles in a murine model of subarachnoid hemorrhage. Genes Brain Behav. 2021 Jun;20(5):e12728. doi: 10.1111/gbb.12728.
6. Zheng ZV, Lyu H, Lam SYE, Lam PK, Poon WS, Wong GKC*. The Dynamics of Microglial Polarization Reveal the Resident Neuroinflammatory Responses After Subarachnoid Hemorrhage. Transl Stroke Res. 2020 Jun;11(3):433-449. doi: 10.1007/s12975-019-00728-5.
7. Lu G, Wong MS, Xiong MZQ, Leung CK, Su XW, Zhou JY, Poon WS, Zheng VZY, Chan WY, Wong GK*. Circulating MicroRNAs in Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage. J Am Heart Assoc. 2017 Apr 25; 6(4). pii: e005363. doi: 10.1161/JAHA.116.005363.
8. Su XW, Chan AH, Lu G, Lin M, Sze J, Zhou JY, Poon WS, Liu Q, Zheng VZ, Wong GK*. Circulating microRNA 132-3p and 324-3p Profiles in Patients after Acute Aneurysmal Subarachnoid Hemorrhage. PLoS One. 2015; 10(12):e0144724.
9. Wong GK*, Nung RC, Sitt JC, Mok VC, Wong A, Ho FL, Poon WS, Wang D, Abrigo J, Siu DY. Location, Infarct Load, and 3-Month Outcomes of Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage. Stroke. 2015 Nov;46(11):3099-104. doi: 10.1161/STROKEAHA.115.010844.
10. Wong GK*, Chan DY, Siu DY, Zee BC, Poon WS, Chan MT, Gin T, Leung M, HDS-SAH Investigators. High dose simvastatin for aneurysmal subarachnoid hemorrhage. Stroke. 2015 Feb;46(2):382-8. doi: 10.1161/STROKEAHA.114.007006.
11. Wong GK*, Lam SW, Ngai K, Wong A, Poon WS, Mok V, Cognitive Dysfunction after Aneurysmal Subarachnoid Haemorrhage Investigators. Cognitive domain deficits in patients with aneurysmal subarachnoid haemorrhage at 1 year. J Neurol Neurosurg Psychiatry. 2013 Sep;84(9):1054-8. doi: 10.1136/jnnp-2012-304517.
12. Wong GK*, Lam S, Ngai K, Wong A, Mok V, Poon WS; Cognitive Dysfunction after Aneurysmal Subarachnoid Haemorrhage Investigators. Evaluation of cognitive impairment by the Montreal cognitive assessment in patients with aneurysmal subarachnoid haemorrhage: prevalence, risk factors and correlations with 3 month outcomes. J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1112-7. doi: 10.1136/jnnp-2012-302217.
13. Wong GK*, Yeung JH, Graham CA, Zhu XL, Rainer TH, Poon WS. Neurological outcome in patients with traumatic brain injury and its relationship with computed tomography patterns of traumatic subarachnoid hemorrhage. J Neurosurg. 2011 Jun;114(6):1510-5. doi: 10.3171/2011.1.JNS101102.
14. Wong GK*, Yeung DK, Ahuja AT, King AD, Lam CW, Chan MT, Gin T, Poon WS. Intracellular free magnesium of brain and cerebral phosphorus-containing metabolites after subarachnoid hemorrhage and hypermagnesemic treatment: a ³¹P–magnetic resonance spectroscopy study. Clinical article. J Neurosurg. 2010 Oct;113(4):763-9. doi: 10.3171/2009.10.JNS09915.
15. Wong GK, Zhu CX, Ahuja AT, Poon WS. Craniotomy and clipping of intracranial aneurysm in a stereoscopic virtual reality environment. Neurosurgery. 2007 Sep;61(3):564-8; discussion 568-9. doi: 10.1227/01.NEU.0000290904.46061.0D.