Students

Name: Ziheng Huang

Post: Full-time Ph.D (Three years)

Enrolled: August 2021-persent

Origin: Mainland China

First Degree: Bachelor of Science in Bioinformatics, Harbin Medical University, Heilongjiang, PRC

Master’s degree: Master of Science in Biomedical Engineering, Harbin Medical University, Heilongjiang, PRC

Supervisor: Prof. William Wu

Title of Thesis:

The Mechanism of Cancer on the Evolution of the Human Genome

Publications: ORCID 0000-0002-6643-5707

Xiujie Chen^1,* , Lei Liu^1,*, YunFeng Wang^1,*, Bo Liu^1,*, Diheng Zeng¹, Qing Jin¹, MengJian Li¹, DeNan Zhang¹, Qiuqi Liu¹, Hongbo Xie¹, “Identification of breast cancer recurrence risk factors based on functional pathways in tumor and normal tissues”. Oncotarget. 2017 Mar 28;8(13):20679-20694.
Hongbo Xie^1,*, Diheng Zeng^1,*, Xiujie Chen^1,*, Diwei Huo^2,*, Lei Liu¹, Denan Zhang¹, Qing Jin¹, Kehui Ke¹ and Ming Hu¹, “Prediction on the risk population of idiosyncratic adverse reactions based on molecular docking with mutant proteins”. Oncotarget. 2017 Oct 5;8(56):95568-95576.
Huan Liu^#, Jinpu Wei^#, Ting Yang^#, Weixue Mu, Bo Song, Tuo Yang, Yuan Fu, Xuebing Wang, Guohai Hu, Wangsheng Li, Hongcheng Zhou, Yue Chang, Xiaoli Chen, Hongyun Chen, Le Cheng, Xuefei He, Hechen Cai, Xianchu Cai, Mei Wang, Yang Li, Sunil Kumar Sahu, Jinlong Yang, Yu Wang, Ranchang Mu, Jie Liu, Jianming Zhao, Ziheng Huang, Xun Xu, Xin Liu^*,“Molecular digitization of a botanical garden: high-depth whole genome sequencing of 689 vascular plant species from the Ruili Botanical Garden”. GigaScience, 2019, giz007, https://doi.org/10.1093/gigascience/giz007
Iqbal N, Liu X, Yang T, Huang Z, Hanif Q, Asif M, et al. (2019) Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan. PLoS ONE 14(4): e0215065. https://doi.org/10.1371/journal.pone.0215065
Ye Yin^*, Ting Yang^*, Huan Liu^*, Ziheng Huang, Yaolei Zhang, Yue Song, Wenliang Wang, Karstn Kristiansen. The draft genome of mandrill (Mandrillus sphinx): An Old World monkey. Sci Rep 10, 2431 (2020). https://doi.org/10.1038/s41598-020-59110-3
Fang S, Zhang L, Liu Y, Xu W, Wu W, Huang Z, Wang X, Liu H, Sun Y, Zhang R, Peng B, Liu X, Sun X, Yu J, Chan FKL, Ng SC, Wong SH, Wang MHT, Gin T, Joynt GM, Hui DSC, Feng T, Wu WKK, Chan MTV, Zou X, Xia J. Lysosome activation in peripheral blood mononuclear cells and prognostic significance of circulating LC3B in COVID-19. Brief Bioinform. 2021 Mar 22;22(2):1466-1475. doi: 10.1093/bib/bbab043. PMID: 33620066; PMCID: PMC7929326.
Li Z, Huang Z, Li X, Huang C, Shen J, Li S, Zhang L, Wong SH, Chan MTV, Wu WKK. Bioinformatic analyses hinted at augmented T helper 17 cell differentiation and cytokine response as the central mechanism of COVID-19-associated Guillain-Barré syndrome. Cell Prolif. 2021 May;54(5):e13024. doi: 10.1111/cpr.13024. Epub 2021 Mar 10. PMID: 33751722; PMCID: PMC8088459.
Huang D, Wang X, Liu Y, Huang Z, Hu X, Hu W, Li Q, Chan H, Zou Y, Ho IHT, Wang Y, Cheng ASL, Kang W, To KF, Wang MHT, Wong SH, Yu J, Gin T, Zhang Q, Li Z, Shen J, Zhang L, Chan MTV, Liu X, Wu WKK. Multi-omic analysis suggests tumor suppressor genes evolved specific promoter features to optimize cancer resistance. Brief Bioinform. 2021 Mar 30:bbab040. doi: 10.1093/bib/bbab040. Epub ahead of print. PMID: 33783485.