發育及再生生物學
The Developmental and Regenerative Biology (DRB) Thematic Research Program covers four specific, but complimentary, research areas listed below. Members are interested in the cellular and molecular mechanisms of how embryos, tissues and stem cells are formed, develop, function and degenerate. Also how factors such as signalling molecules, hormones, growth factors and cytokines control these important processes. Outcome of these researches will help how we understand what is needed to recreate tissue and organs, including new drugs that could be used in regenerative medicine.
Reproductive Biology
- Functional genomics and epigenetics in germ cell and gonad development
- Role of the hypothalamic-pituitary-gonadal axis in health and disease
- Delineating molecular mechanisms underlying germ cell ageing
Developmental Biology
- Using mouse, Xenopus and zebrafish embryos as models to elucidate fundamental development processes
- Foetal development in health and disease: genetics, genomics and the development of biomarkers
Endocrinology
- Hormone action and signal transduction
- Pancreatic physiology and diabetes
- Endocrine disorders : molecular biology and treatment by stem cells and therapeutic agents
- Intracellular protein trafficking and hypothalamic/pituitary hormone secretion
Stem Cells and Regenerative biology
- Investigating fundamental biological and mechanical factors that regulate stem cell proliferation, differentiation and developmental fate
- Use of stem cells and 3D scaffold-printing to generate tissues and organs for regeneration such bone fracture healing, cardiovascular and neural tissue repair etc.
- Reprograming normal and genetically abnormal somatic cells into induced pluripotent stem cell (iPS) and using them as models to study human diseases and developmental processes
- Germline stem cell transdifferentiation for tissue regeneration
| Name | Contact No. | Research Interests |
| Prof BLOCKI Anna Maria | 3943 9797 | Tissue engineering, regenerative medicine, biomaterials, stem cells, cell-based therapy, hydrogel, extracellular matrix |
| 3943 3032 | Tissue engineering, liver regeneration, stem cell, microfluidics, biomaterial, biomechanics |
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| 3943 1383 |
Genetic diseases, germ cells, differentiation, |
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Prof CHAN Wood Yee (Chief)
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3943 6895 | Stem cell therapy, development of enteric nervous system, neural crest stem cells, stem cell migration and differentiation, congenital gut disorders, cell transplantation, mouse embryonicdevelopment, Hirschsprung's disease, irritable bowel syndrome, neural crest cell induction |
| 3943 9796 | Stem cell differentiation and aging | |
| Prof DALTON Stephen 杜卓勳教授 |
3943 0537 | Pluripotent and adult stem cells, Cardiac development, Brown and beige adipocytes, Therapeutic development for type 2 diabetes |
| 3943 1455 | Genome editing, Stem cells, Gene and cell therapy, Inherited hematopoietic and metabolic disorders |
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| 3943 9986 | Infertility, assisted reproduction technologies, male contraceptive, sperm functions, spermatogenesis, germline stem cell biology, germ cell transplantation, testis microenvironment, cancer/testis genes |
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| 3943 6801 | Skeletal Biology, Skeletal Disorders, Wnt/PCP signaling in development and disease | |
| 3943 5747 | Molecular mechanisms of deleterious genetic alterations in inheritable human diseases |
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| Prof JIANG Xiaohua 蔣曉華教授 |
3943 1229 | Stem cell epigenetics, stem cell therapy, stem cell microenvironment, aging |
| 3943 4497 | Muscloskeletal biology, tissue engineering, regenerative medicine, functionally-graded biomaterials, artificial intelligence, machine learning, cell tracking, computer vision |
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| Prof KO Wing Hung 高永雄教授 |
3943 6781 | Epithelial transport, Ca2+/cAMP signaling, purinergic receptors, Heme oxygenase, carbon monoxide, airway inflammation, fluorescence imaging |
| 3943 0415 | Molecular mechanisms of mammalian development and human congenital disorders, transcriptional regulation, functional genomics, craniofacial, inner ear and sensory neural development, neural crest and placode, stem cells and regeneration |
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| 3943 5204 | ||
| 3943 4494 | Bone, cartilage, degeneration, regeneration, stem cells, small molecules, tissue engineering |
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| 3943 4497 | Bone tendon tissue engineering, extracellular matrix, stem cells, immunomodulation |
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| Prof XIA Yin 夏銀教授 |
3943 4480 | Kidney physiology, injury and repair, Male reproductive biology, Metabolic signaling pathways in the liver |
| 3943 1344 | Embryonic development, tumorigenesis of neuroblastoma, tissue regeneration and therapy |
| Name | Contact No. | Research Interests |
| Prof JIANG Yangzi | 3943 5153 | Tissue Degeneration and Tissue Regeneration: Osteoarthritis |
| Prof SO Kam Hei Karl | 3943 0416 | Mammalian development and human congenital disorders, myogenesis, craniofacial development, transcriptional regulation, placode, single-cell genomics, epigenetics |
| Prof WANG Wuming | 3943 0570 | ESC pluripotency, cardiac development and disease, genome editing |
| Name | Contact No. |
| Prof CHAN Chung Ngor Juliana | 3505 3138 |
| Dr CHAN Leung Kwok Clement | --- |
| Prof CHENG Chun Yiu Jack | 3505 2729 |
| Prof CHOY Kwong Wai Richard | 3505 3099 |
| Prof LEUNG Ting Fan | 3505 2860 / 3505 2850 |
| Prof LI Gang | 3505 3592 / 3763 6153 |
| Prof POON Wai Sang | 3505 2624 |
| Prof TANG Leung Sang Nelson | 3505 2320 |
| Prof WANG Huating | 3763 6047 |
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