韋妙宜教授
教授
- mary-waye@cuhk.edu.hk
- 3943 9302
- BSc, PhD
- ELB632
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研究領域 |
Study of Association of Genetic Variants with Human Conditions, including Psychiatric Disorders |
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簡歷
Professor Waye received the degree of Bachelor of Science (Hon) from the University of Western Ontario, Canada, majoring in Bacteriology and Immunology, and then took graduate work and received Ph.D. in Medical Biophysics at the University of Toronto, Canada. During her graduate period, she received support as a research student of the National Cancer Institute. In completing her Ph.D. she received a King George V Fellowship and received her post-doctoral training at the Laboratory of Molecular Biology, Medical Research Council, Cambridge, UK as a National Cancer Institute Research Fellow. She did research in the Division of Protein and Nucleic Acid and later also received training in the Division of Structural Studies in Cambridge. She returned to the University of Toronto as an assistant professor. She has been at The Chinese University of Hong Kong since 1992. She was appointed as the Founding Director of the Croucher Laboratory for Human Genomics in 2004.
獎項及榮譽
| Sub Category | Awards & Honour |
|---|---|
| 研究獎項 | Silver Poster Award at Global Proteome Research Congress, Human Proteome Organization (2004) |
| 榮譽 | King George V Fellowship |
| 榮譽 | Top applicant of National Cancer Institute of Canada Research Fellow (1982) |
| 榮譽 | NCI Post-doctoral Fellowship, National Cancer Institute of Canada (1982–1985) |
| 榮譽 | A publication ranked third in LetPub’s in citation ranking for 2015 Medical articles published by Chinese authors (2015年醫學領域中國作者發表的高被引研究論文排行榜排名第三) : Liang, W. C., Fu, W. M., Wong, C. W., Wang, Y., Wang, W. M., Hu, G. X., … Waye, M. M. Y. (2015). The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer. ONCOTARGET, 6(26), 22513-22525. |
校外服務
| Sub Category | Awards & Honours |
|---|---|
| 榮譽委任 | Adjunct Professor, School of Biomedical Sciences, The Chinese University of Hong Kong (2014 – 2016) |
| 榮譽委任 | Assistant Professor (cross appointment), Department of Microbiology, Faculty of Medicine, University of Toronto (1991 – 1992) |
| 編輯職務 | Editor in chief, Journal of Biochemistry and Molecular Biology in the Post Genomic Era (2011 – 2014) |
| 編輯職務 | Editor (Chinese translation), Influenza Report 2006 |
| 編輯職務 | Chinese Translator, Supercourse lecture on Myths and Realities of Ebola Virus Disease 2014 |
| 專業服務 | Vice-Chairperson, Hong Kong Association of Specific Learning Disabilities (2019 – 2021) |
| 專業服務 | Founding President, Hong Kong Society of Behavioural and Neural Genetics (2011 – present) |
| 專業服務 | President, Hong Kong Society of Biochemistry and Molecular Biology (2006 – 2018) |
| 專業服務 | Member, American Association for the Advancement of Science (1990 – 2014) |
| 專業服務 | Member, American Society for Cell Biology (1990 – 2014) |
| 專業服務 | Member, Canadian Society of Cell Biologists (1978 – 2014) |
| 專業服務 | Lifetime Member, Cell Stress Society International (1999 – present) |
| 專業服務 | Member, Hong Kong Association For Specific Learning Disabilities (2003 – present) |
| 專業服務 | Member, Hong Kong Society of Medical Genetics (1992 – 2014) |
| 專業服務 | Member, Human Genome Organization (1999 – 2014) |
| 專業服務 | Member, Human Proteome Organization (2003 – 2014) |
| 專業服務 | Member, International Society of Computational Biology (1997 – 2014) |
| 專業服務 | Member, Society for the study for Endocrinology, Metabolism and Reproduction, Hong Kong (1992 – 2014) |
| 專業服務 | Lifetime Member, Society of Chinese Bioscientists in America (1988 – present) |
| 專業服務 | Member, Hong Kong Society of Child Neurology & Developmental Paediatrics (2005 – present) |
| 專業服務 | Member of the Grant Panel on Engineering and Science, University of Macau (2011–2016) |
| 專業服務 | Member of the Research Programme Sub-committee, Centre for Emerging Infectious Diseases, School of Public Health, Faculty of Medicine, The Chinese University of Hong Kong (2004 – 2006) |
| 專業服務 | Judge, Hong Kong Awards for Industry: Technological Achievement, HKSTP (2005 – 2006) |
| 專業服務 | Ad hoc Reviewer, Asia-Pacific Psychiatry, Oncogene, Genomics, Genes, BioTechniques, Developmental Medicine & Child Neurology, BMC Medical Genetics, Progress in Neuro-Psychopharmacology and Biological Psychiatry and Experimental Cell Research |
| 專業服務 | Ad hoc Reviewer for grant proposal, Wellcome Trust, UK |
| 專業服務 | Ad hoc Reviewer for faculty employment/promotion for universities in Singapore, Taiwan, Malaysia and Macau |
主要研究撥款
(最近五年以首席研究員或合作研究員身分獲得之主要研究撥款)
| 撥款來源 | 項目名稱 |
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| Research Institute for Smart Ageing, PolyU | Quantification of brain age by functional MRI data: Complexity and functional connectivity |
| Health Care and Promotion Scheme | New wine in old bottle: The effects of SUDOKU Mind Activation and Revitalizing Training (SMART) Program on cognitive function among people with mild cognitive impairment |
主要學術著作
(最近三年發表的十篇主要論文)
| Publications |
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| Chan, C. W. H., Law, B. M. H., Ng, M. S. N., Wong, C. C. Y., Wong, C. W. Y., Quinley, M., Orgusyan, J. M., Chow, K. M., & Maye, M. M. Y. (2021). Association of single nucleotide polymorphisms of cytochrome P450 enzymes with experience of vasomotor, vaginal and musculoskeletal symptoms among breast cancer patients: A systematic review. BMC Cancer, 21(1), 570. |
| Maggu, A. R., Lau, J. C. Y., Waye, M. M. Y., & Wong, P. C. M. (2021). Combination of absolute pitch and tone language experience enhances lexical tone perception. Sci Rep., 11(1), 1485. |
| Sabit, H., Tombuloglu, H., Rehman, S., Almandil, N. B., Cevik, E., Abdel-Ghany, S., Rashwan, S., Abasiyanik, M.,Waye, M. (2021). Gut microbiota metabolites in autistic children: An epigenetic perspective. Heliyon, 7(1), e06105. |
| Cheung, D. W. S., Koon, J. C. M., Wong, P. H., Yau, K. C., Wat, E. C. L., Chan, J. Y. W., Lau, V. K. M., Ko, E. C. H., Waye, M. M Y., & Fung, K. P. (2021). Combination of atorvastatin or hydrochlorothiazide/amlodipine with Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) for atherosclerosis, hyperlipidaemia, and hypertension: A preclinical in vivo study (abridged secondary publication). Hong Kong Medical Journal, 27 Suppl 2(3), 18–22. |
| Chan, C. W. H., Law, B. M. H., So, W. K. W., Chow, K. M., & Waye, M. M. Y. (2020). Pharmacogenomics of breast cancer: highlighting CYP2D6 and tamoxifen. J Cancer Res Clin Oncol, 146(6), 1395–1404. |
| Chan, H. C., Lau, Y. T., Ding, Q., Li, C. K., Wong, C. M., Shaw, P. C., Waye, M. M. Y., & Tsang, S. Y. (2020). Pinx1t, a novel pinx1 transcript variant, positively regulates cardiogenesis of embryonic stem cells. J Am Heart Assoc, 9(6), e010240. |
| Rao, S., Shi, M., Han, X., Lam, M. H. B., Chien, W. T., Zhou, K. , Liu, G., Wing, Y. K., So, H. C., & Waye, M. M. Y. (2020). Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder. Gene, 755, 144901. |
| Chan, C. W. H., Law, B. M. H., Waye, M. M Y., Chan, J. Y. W., So, W. K. W., & Chow, K. M. (2019). Trimethylamine-N-oxide as one hypothetical link for the relationship between intestinal microbiota and cancer – Where we are and where shall we go? J Cancer, 10(23), 5874–5882. |
| Rao, S., Han, X., Shi, M., Siu, C. O., Waye, M. M. Y., Liu, G., & Wing, Y. K. (2019). Associations of the serotonin transporter promoter polymorphism (5-HTTLPR) with bipolar disorder and treatment response: A systematic review and meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry, 89, 214–226. |
| Liang, W. C., Wong, C. W., Liang, P. P., Shi, M., Cao, Y., Rao, S. T., Tsui, S. K. W., Waye, M. M. Y., Zhang, Q., Fu, W. M., & Zhang, J. F. (2019). Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway. Genome Biol., 20(1), 84. |