CChem FRSC CSci
Professor
Room 358 Science Centre
(852) 3943 6375
(852) 2603 5057
Education
| 1990-1993 | D.Phil. in Chemistry Balliol College, University of Oxford |
| 1988-1990 | M.Phil. in Chemistry The Chinese University of Hong Kong |
| 1984-1988 | B.Sc. (Hons.) in Chemistry, First Class Chung Chi College, The Chinese University of Hong Kong |
Positions
| Since 2002 | Professor, Department of Chemistry, The Chinese University of Hong Kong |
| Since 2002 | Warden, Pentecostal Mission Hall Complex (High Block) Chung Chi College, The Chinese University of Hong Kong |
| 2017-2021 | Pro-Vice-Chancellor/Vice-President, The Chinese University of Hong Kong |
| 2019-2020 | Acting University Dean of Students, The Chinese University of Hong Kong |
| 2011-2017 | Associate Vice-President, The Chinese University of Hong Kong |
| 2009-2017 | University Dean of Students, The Chinese University of Hong Kong |
| 2004-2008 | Associate Dean (Student Affairs), Faculty of Science, The Chinese University of Hong Kong |
| 2002-2005 | Part-Time Professor, Fuzhou University, China |
| 2001-2004 | Associate Director, Applied Chemistry with Management Studies Programme, The Chinese University of Hong Kong |
| 1997-2000 | Part-Time Lecturer, School of Pharmacy, The Chinese University of Hong Kong |
| 1994-2002 | Lecturer in Chemistry, The Chinese University of Hong Kong |
| 1993-1994 | Research Fellow in Chemistry, California Institute of Technology, USA |
Research Interests
| Our current research interests lie in the chemistry of various functional dyes, particularly phthalocyanines and boron dipyrromethene derivatives, focusing on their synthesis, supramolecular chemistry, bioconjugation, bioorthogonal chemistry and applications in photodynamic therapy, photothermal therapy, bioimaging, fluorescence sensing, logic devices and renewable energy production. The ongoing projects include: |
| A. | Design and preparation of multifunctional molecular and nano-photoresponsive agents for targeted phototherapies |
| B. | Use of supramolecular and bioorthogonal chemistry for advanced theranostic applications |
| C. | Development of efficient peptide and protein conjugation methods |
| D. | Development of molecular-based fluorescent sensors and logic devices |
| E. | Synthetic studies and applications of low-symmetry phthalocyanines |
| F. | Exploration of phthalocyanine-based materials for CO2 fixation, water splitting and batteries |
Honours and Awards
| 2000, 2009, 2013,2020 | Faculty Exemplary Teaching Award, The Chinese University of Hong Kong |
| 2009 | The Vice-Chancellor’s Exemplary Teaching Award, The Chinese University of Hong Kong |
| 2005 | Young Researcher Award, The Chinese University of Hong Kong |
| 1990-1993 | Croucher Foundation Scholarship |
| 1988-1990 | Croucher Foundation Studentship |
Professional Qualifications
| Nov. 2004 | Chartered Scientist (CSci), Science Council, UK |
| Jul. 2000 | Fellow of the Royal Society of Chemistry (FRSC) |
| Mar. 1993 | Chartered Chemist, Member of the Royal Society of Chemistry (CChem MRSC) |
Teaching Experience
| A. | Undergraduate Teaching Subjects: Transition Metal Chemistry, Fundamental of Spectroscopic Analysis |
| B. | Postgraduate Being the supervisor of 37 Ph.D. students (30 of them have completed their study) and 14 M.Phil. students (all of them have graduated) |
| Group Members (Past & Present) |
Publications
| Full List of Publications | |
| Total Number of Publications = 245 | |
| Number of Citations = 9,514 | |
| H-index = 59 | |
| (taken from Scopus as of June 20, 2022) |
External Research Grants (As Principal Investigator for the last 5 years)
(1) Project: Selective Photodynamic Eradication of Senescent Cells with b-Galactosidase-Activated Photosensitizers (Ref. No. CUHK14307518)
Grant: RGC General Research Fund 2018-19 – HK$ 505,298
Period: Jan. 1, 2019 – Dec. 31, 2021
(2) Project: Targeted Delivery and Activation of Photosensitizers for Photodynamic Therapy using Supramolecular Bioorthogonal Chemistry (Ref. No. CUHK14307719)
Grant: RGC General Research Fund 2019-20 – HK$ 558,272
Period: Sep. 1, 2019 – Aug. 31, 2022
(3) Project: Tumor-Selective Activatable Polydopamine-Based Nanophotosensitizers for Targeted Photodynamic Therapy (Ref. No. CUHK14306320)
Grant: RGC General Research Fund 2020-21 – HK$ 441,074
Period: Sep. 1, 2020 – Aug. 31, 2023
(4) Project: Dual Receptor-Mediated Endocytosis of Bioorthogonal Components for Site-Specific Activation of Photodynamic Therapy (Ref. No. CUHK14307321)
Grant: RGC General Research Fund 2021-22 – HK$ 806,375
Period: Sep. 1, 2021 – Aug. 31, 2024
(5) Project: Development of Novel Cell Penetrating Peptide-Conjugated Drugs for Treatment of Ocular Uveitis (Ref. No. PRP/015/21FX)
Grant: Innovation and Technology Commission (ITC) Partnership Research Programme – HK$ 1,715,800
ITC Research Talent Hub – HK$ 3,291,635
Period: Feb. 4, 2022 – Jul. 31, 2024
Editorial Work
- Editorial Board Member, Colorants
- Editorial Board Member, Nanomaterials
- Guest Editor for the “Special Collection on Photodynamic Therapy” in ChemPlusChem