Vice-Chancellor Assistant Professor
Room 160 Science Centre
(852) 3943 6371
Education
| 2014-2018 | Ph. D. , The Chinese University of Hong Kong | |
| 2010-2014 | B. Sc. , Nankai University | |
Positions
| Since 2022 | Vice-Chancellor Assistant Professor, The Chinese University of Hong Kong |
| 2019 – 2022 | Postdoctoral Scholar, University of Chicago |
| 2018 – 2019 | Research Associate, The Chinese University of Hong Kong |
Research Interests
| Main group chemistry, organic synthesis, catalysis, electrochemical reactions |
| Synthetic methodologies involving transition metal catalysis and photo-/electro-catalysis |
| Design, preparation and property study of new organoboron compounds, including borylation reagents and boron-containing functional materials |
| Application of the newly developed reagents and protocols in the synthesis and late-stage functionalization of drug molecules |
Honors and Awards
| 2024 | Croucher Tak Wah Mak Innovation Awards 2024 |
| 2021 | Suzuki Postdoctoral Fellowship Award |
| 2019 | Ministry of Education Higher Education Outstanding Scientific Research Output Awards, Second-class Award in Natural Sciences |
| 2014-2018 | Hong Kong PhD Fellowship |
Representative Publications
| 1. | Lou, X.; Lin, J.; Kwok, C. Y.; Lyu, H.* “Stereoselective Unsymmetrical 1,1-Diborylation of Alkynes with a Neutral sp2-sp3 Diboron Reagent.” Angew. Chem. Int. Ed. 2023, 62, e202312633. (Highlighted in Synlett, Synlett 2024, DOI: 10.1055/s-0042-1751580) |
| 2. | Tao, H.; Lyu, H.* “Functionalization of Boranes through Thiol/Oxygen Catalysis” Chin. J. Chem. 2024, DOI: 10.10022/cjoc.202400494. |
| 3. | Lyu, H.; Tugwell, T. H.; Chen, Z.; Kukier, G. A.; Turlik, A.; Wu, Y.; Houk, K. N.; Liu, P.; Dong, G. “Modular Synthesis of 1,2-Azaborines via Ring-Opening BN-isostere Benzannulation.” Nat. Chem. 2023, DOI: 10.1038/s41557-023-01343-6. |
| 4. | Lyu, H.; Kevlishvili, I.; Xuan, Y.; Liu, P.; Dong, G. “Boron Insertion into Alkyl Ether Bonds via Zinc/Nickel Tandem Catalysis.” Science 2021, 372, 175-182. |
| 5. | Au, Y. K.;† Lyu, H.;† Quan, Y.; Xie, Z. “Copper-Catalyzed Electrochemical Selective B–H Oxygenation of o-Carboranes at Room Temperature.” J. Am. Chem. Soc. 2020, 142, 6940-6945. (†co-first author) |
| 6. | Lyu, H.; Zhang, J.; Yang, J.; Quan, Y.; Xie, Z. “Catalytic Regioselective Cage B(8)-H Arylation of o-Carboranes via “Cage-Walking” Strategy.” J. Am. Chem. Soc. 2019, 141, 4219-4224. |
| 7. | Lyu, H.; Quan, Y.; Xie, Z. “Transition Metal Catalyzed Direct Amination of Cage B(4)−H Bond in o-Carboranes: Synthesis of Tertiary, Secondary and Primary o-Carboranyl Amines.” J. Am. Chem. Soc. 2016, 138, 12727-12730. |
| 8. | Lyu, H.; Quan, Y.; Xie, Z. “Rhodium-Catalyzed Regioselective Hydroxylation of Cage B−H Bonds of o-Carboranes with O2 or Air.” Angew. Chem., Int. Ed. 2016, 55, 11840-11844. |