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​Prof. Benjamin Hon-kei YIP 葉漢基教授

叶汉基教授

Prof. Benjamin Hon-kei YIP

BSc (Örebro University, Swe), PhD (Karolinska Institutet, Swe)

助理教授

电邮: benyip@cuhk.edu.hk

 

ORCID: 0000-0002-4749-7611

Scopus Author ID: 55589080100

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个人简介

叶汉基教授于2011年加入香港中文大学公共卫生与基层医疗学院，现为助理教授。2008年，他在瑞典卡罗林斯卡学院获得博士学位。他的论文是开发估计家谱数据中疾病倾向性和相关性的方差分量的随机效应模型的统计方法。叶教授与他的博士生导师Yudi Pawitan教授一起，在一个大规模的人口样本中研究了精神分裂症和双相情感疾病之间的共病性和倾向性。这项研究结束了精神病学中最持久的争论之一，即精神分裂症和躁郁症是完全不同还是与相同病因过程的临床实现（Lancet 2009）。他继续发展和完善这些方法，体现在最近国际顶级同行评审稿件中发表的文章（JAMA Psychiatry 2019 ，Biological Psychiatry 2018，2020）。

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在卡罗林斯卡学院继续从事遗传流行病学研究的同时，叶教授还担任多项临床研究的首席统计学家，包括临床试验和队列研究，家庭健康账户指导委员会成员，服务学习委员会成员（崇基学院），以及世界大学多发病综合护理模式工作小组的主要成员。他正在教授卫生经济学的本科和研究生课程。目前，他正在指导4名博士生。在此之前，他曾指导/共同指导其他四名已毕业的博士生。

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叶教授是许多资助项目的主要研究者或首席生物统计学家（见下文）。他有83篇学术文章（更新于20/07/2020），h指数为17。完整的论文列表请见 ：

https://www.ncbi.nlm.nih.gov/myncbi/1Jiy6rs2e8zkdf/bibliography/public/

研究方向

  • 心理健康：自闭症谱系障碍的流行病学和遗传流行病学；

  • 电子健康：可穿戴性、监测、行为

  • 卫生经济学：基于试验的经济评估

​近期获资助研究项目

  • As Principal Investigator or Co-Principal Investigator

    • Sex Differences in Autism Spectrum Disorder: A Population-based Genetic Epidemiological Study. (ECS24108520, 2020)

    • The Hong Kong Mental Morbidity Survey for Older People – HKMMSOP (FHB, 2019-2022)

    • Post-discharge health care utilization and needs among young stroke patients: a prospective cohort study (CUHK Direct Grant 143386979, 2020-2021)

    • Integrating Health & Social Care Services to Tackle Asia’s Ageing Population & Rise in Chronic & Multi- Morbidity: Global Developments & Lessons (WUN RDF 4930631, 2020 – 2021)

 

  • As Co-Investigator

    • Effectiveness of a Complex Exercise Intervention to Normalize Blood Pressure and Its Nocturnal Dipping in Patients with Hypertension in Primary Care: A Randomized-controlled Trial (Co-I, HMRF136636363, 2020-2023)

    • Novel Retinal Imaging Biomarkers for Children Amblyopia (Co-I, HMRF136635437, 2020-2023)

    • Preventing Curve Progression and the Need for Bracing in Early Diagnosed Adolescent Idiopathic Scoliosis Using Calcium Plus Vitamin D Supplementation – A Randomized Double-blinded Placebo-controlled Trial (Co-I, GRF138172334, 2018-2023)

    • Low-Concentration Atropine for Myopia Progression (LAMP) Phase 4 Study: 5-year follow up to evaluate the optimal treatment regimen and long-term efficacy of low-concentration atropine eye drops (GRF138277701, 2020-2022)

    • Incidence, Clinical Presentation, Treatment Modalities, and Long Term Outcomes of Retinoblastoma in Hong Kong: Hong Kong Retinoblastoma Registry (HMRF136630353, 2020-2022)

    • Tender for the Provision of Services of the Monitoring and Evaluation Study of Kwai Tsing District Health Centre (FHB136603387, 2019-2022)

    • Combining Mind-body Physical Exercise, Cognitive Training, and Nurse-led Risk Factor Modification to Enhance Cognition among Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial (HMRF136562162, 2019-2022)

    • Complex Interventions for Reducing 30-day Avoidable Hospital Readmission among Adults: Recommendations for Hong Kong via Overview of Systematic Reviews and Stakeholder Consensus (HMRF136561236, 2019-2022)

    • Vibration Therapy as a Primary Prevention Strategy of Fragility Fracture, a Local Invention for the Local Community (Research Committee Group Research Scheme CUHK 136553354, 2020-2021)

    • Do Women with a History of Recurrent Miscarriage Have a Higher Risk of Obstetric and Perinatal Complications in a Subsequent Pregnancy? A Cohort Study (HMRF136594341, 2020-2021)

    • The Feasibility and Effects of Mindfulness Based Relapse Prevention (MBRP) on Reducing Craving and Addictive Behaviour in Local Adults with Substance Abuse Disorders (Beat Drugs Fund 136611718, 2019-2021)

    • Exposure to Alcohol Social Media Marketing and Associations with Young Adult''s Drinking Expectancies and Behaviours: A Study to Inform Regulation and Health Promotion (HMRF136628500, 2020-2021)

    • The Effect of Virtual Reality Phacoemulsification Cataract Extraction Simulation Surgery Training on Patient Safety and Outcomes: A Randomised Controlled Trial (VRPhaco Sim Study) (HMRF136434203, 2018-2021)

    • The effects of a mindfulness based intervention - MYmind - for children with ADHD and their parents: a randomised controlled trial (HMRF 138201888, 2018-2020)

    • Building Capacity to Promote Winter Health in Elderly: Co-production of a Volunteer-based Home Care Programme for Post-discharged Elderlies by Medical-social-academic Sector (HCPS 136453631, 2018-2020)

    • Harms and Second-hand Harms of Alcohol Consumption in Hong Kong: A Population-based Study to Inform Public Policy (HMRF136572358, 2019-2020)

    • Feasibility and Acceptability of World Health Organization’s “Best Buys” for Reducing the Harms of Alcohol Use in Hong Kong: Comparison of Population Attitudes and Stakeholder''s Opinions. (GRF 138207457, 2017-2020)

部份学术文章

  1. Bai D, Marrus N, Yip BHK, Reichenberg A, Constantino JN, Sandin S. Inherited Risk for Autism Through Maternal and Paternal Lineage. Biol Psychiatry. 2020 Apr 2:S0006-3223(20)31384-6. doi:10.1016/j.biopsych.2020.03.013.

  2. Bai D, Yip BHK, Windham GC, Sourander A, Francis R, Yoffe R, Glasson E, Mahjani B, Suominen A, Leonard H, Gissler M, Buxbaum JD, Wong K, Schendel D, Kodesh A, Breshnahan M, Levine SZ, Parner ET, Hansen SN, Hultman C, Reichenberg A, Sandin S. Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort. JAMA Psychiatry. 2019 Jul 17;. doi: 10.1001/jamapsychiatry.2019.1411.

  3. Yip BHK*, Bai D, Mahjani B, Klei L, Pawitan Y, Hultman CM, Grice DE, Roeder K, Buxbaum JD, Devlin B, Reichenberg A, Sandin S. Heritable Variation, With Little or No Maternal Effect , Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden. Biological Psychiatry. 2018;83:589–97.

  4. Yip BHK*, Leonard H, Stock S, Stoltenberg C, Francis RW, Gissler M, Gross R, Schendel D, Sandin S. Caesarean section and risk of autism across gestational age: a multi-national cohort study of 5 million births. International Journal of Epidemiology. 2017;46:429-439.

  5. Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CM. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. The Lancet. 2009;373:234-9.

  6. Yip BH, Pawitan Y, Czene K. Parental age and risk of childhood cancers: A population-based cohort study from Sweden. International Journal of Epidemiology. 2006;35:1495-503

Last Updated: 22 July 2020