ZHANG Xiujuan

Biography

Dr Zhang’s research interests include ocular imaging and community health in pediatric ocular diseases such as myopia, amblyopia and strabismus.  She has led several epidemiological studies on ocular diseases and blindness prevention. She has good experience in studying the risk factors, prevalence, and burden of ocular disorders, visual impairments and in long term studies on the effectiveness of interventions on child ocular health and blindness prevention.

She has more than 20 publications. She is an Editor of the Asia-Pacific Journal of Ophthalmology. She led a s Special Issue titled “Prevalence and Progression of Myopia in Children and Adolescents” of the international journal of “Children”. She also serves as reviewer for international journals, including Ophthalmology.  She has received 4 research grants from Health and Medical Research Fund (HMRF) Hong Kong, Start-up Grant and Direct Grant from CUHK as Principal Investigator and 5 research grants as C-o-Investigator. Dr. Zhang is also committed in community service of children eye care programmes. She helps administer the Hong Kong Children Eye Study, which is a longitudinal epidemiological study of 5,000 children, CUHK Jockey Club Children’s Eye Care programme, which is a major community service programme, as well as an epidemiological study of over 30,000 children and their families.

Research Areas

1. Pediatric ocular diseases: ocular imaging, etiology and risk factors epidemiology, prevention and ocular imaging
2. Myopia: epidemiology, risk factors, intervention
3. Children Eye Studies: territory-based epidemiology and prevention, intervention, and molecular genetics of children eye diseases.
4. Blindness prevention: epidemiology and prevention

Representative Publications:

1. Xiu Juan Zhang, Stephanie S.L. Cheung, Hei-Nga Chan, Yuzhou Zhang, Yu Meng Wang, Benjamin Hon Kei Yip, Ka Wai Kam, Marco Yu, Ching-Yu Cheng, Alvin L. Young, Mike Y.W. Kwan, Patrick Ip, Kelvin K. Chong, Clement C. Tham, Li Jia Chen, Chi Pui Pang, Jason C. Yam. Myopia Incidence and Lifestyle Changes Among School Children During the COVID-19 Pandemic: A Population-based Prospective Study. British Journal of Ophthalmology. 2021 Aug 2:bjophthalmol-2021-319307. doi: 10.1136/bjophthalmol-2021-319307
2. Jason C. Yam, Xiu Juan Zhang, Yuzhou Zhang, Yu Meng Wang, Shu Min Tang, Fen Fen Li, Ka Wai Kam, Simon T. Ko, Benjamin H.K. Yip, Alvin L. Young, Clement C. Tham, Li Jia Chen, Chi Pui Pang. Three-Year Clinical Trial of Low-concentration Atropine for Myopia Progression (LAMP) Study: Continued Versus Washout Phase 3 Report. Ophthalmology. 2021 Oct 7;S0161-6420(21)00745-4. doi: 10.1016/j.ophtha.2021.10.002.
3. Emily S Wong, Xiu-Juan Zhang, Nan Yuan, Jian Li, Chi Pui Pang Pang, Lijia Chen, Clement C. Tham, Carol Y. Cheung, 1 Jason C. Yam. New OCT angiography metrics detects impaired macular microvasculature and correlates with decreased vision in amblyopic eyes: The Hong Kong Children Eye Study. JAMA Ophthalmology. 2020;138(8):858-865. doi:10.1001/jamaophthalmol.2020.2220 (co-first author)
4. Xiujuan Zhang, Emmy Y. Li, Christopher Kai-Shun Leung, David C. Musch, Xin Tang, Chongren Zheng, Mingguang He, David F. Chang, Dennis Shun-Chiu Lam. Diagnostic Accuracy of Rapid Assessment of Avoidable Blindness (RAAB): a Population-based Assessment. American Journal of Ophthalmolog. 2020 May;213:235-243. doi: 10.1016/j.ajo.2019.12.009
5. Lam Alexander, To E, Weinreb RN, Yu M, Mak H, Lai G, Chiu V, Wu K, Xiujuan Zhang, Cheng TPH, Guo PY, Leung CKS. Use of Virtual Reality Simulation to Identify Vision-Related Disability in Patients With Glaucoma. JAMA Ophthalmology. 2020;138 (5):490-498. doi:10.1001/jamaophthalmol.2020.0392
6. Jason C.S. Yam, Fen-Fen Li, Xiujuan Zhang, Shu Min Tang, Benjamin H Yip, Simon T. Ko, Alvin L. Young, Clement C. Tham, Li Jia Chen, Chi Pui Pang. Two-Year Clinical Trial on Low-concentration Atropine for Myopia Progression (LAMP) Study: 0.05% atropine remained the optimal concentration for myopia control. Ophthalmology. 2020 Jul;127(7):910-919. doi: 10.1016/j.ophtha.2019.12.011.
7. Xiu Juan Zhang, Yi Han Lau, Yu Meng Wang, Ka Wai Kam, Alvin L. Young, Li Jia Chen, Patrick Ip, Clement C. Tham, Chi Pui Pang, Jason C. Yam. Prevalence of strabismus and its risk factors in children: Hong Kong Children Eye Study. Scientific Reports. 2021. 2021 Jul 5;11(1):13820. doi: 10.1038/s41598-021-93131-w.
8. Shi Yao Lu, Xiu Juan Zhang, Yu Meng Wang, Nan Yuan, Ka Wai Kam, Poemen P.M. Chan, Pancy O.S. Tam, Wilson W.K. Yip, Alvin L. Young, Clement C. Tham, Chi Pui Pang, Jason C. Yam, Li Jia Chen. Association of SIX1-SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness in children with spatial, age and sex variation. British Journal of Ophthalmology. 2021Aug.
9. Xiujuan Zhang, Emmy Y. Li, Christopher Kai-Shun Leung, David C. Musch, Xin Tang, Chongren Zheng, Mingguang He, David F. Chang, Dennis Shun-Chiu Lam. Prevalence of visual impairment and outcomes of cataract surgery in Chaonan, South China. Plos one. 2017. Aug 10;12(8):e0180769. doi: 10.1371/journal.pone.018076
10. Emmy Y. Li, Yingpeng Liu, Xingkai Zhan, Yuan Bo Liang, Xiujuan Zhang, Chongren Zheng, Vishal Jhanji, Ping Xu, David F. Chang, Dennis S.C. Lam. Prevalence of Blindness and Outcomes of Cataract Surgery in Hainan Province in South China. Ophthalmology. 2013;120:2176-2183

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