The selected publications in prenatal genetic diagnosis, preterm birth, fetal growth restriction, and fetal therapy.
Selected List of Publications
Diagnostic accuracy of the BACs-on-Beads™ assay versus karyotyping for prenatal detection of chromosomal abnormalities: a retrospective consecutive case series.
Choy K, Kwok Y, Cheng Y, Wong K, Wong H, Leung K, Suen K, Adler K, Wang C, Lau T, Schermer M, Lao T, Leung TY.
BJOG 2014; 121:1245-52.
Is High Fetal Nuchal Translucency Associated with Submicroscopic Chromosomal Abnormalities by Array CGH?
Huang J, Poon LC, Akolekar R, Choy KW, Leung TY, Nicolaides KH.
Ultrasound Obstet Gynecol 2014; 43: 620-624.
Noninvasive Prenatal Molecular Karyotyping from Maternal Plasma.
Yu JCY, Jiang PY, Choy KW, Chan AKC, Won HS, Leung WC, Lau ET, Tang MHY, Leung TY, Lo DYM, Chiu RWK
PLos ONE 2013;8(4): e60968
Noninvasive Twin Zygosity Assessment and Aneuploidy Detection by Maternal Plasma DNA Sequencing.
Leung TY, Qu JZZ, Liao GJW, Jiang PY, Cheng YKY, Chan AKC, Chiu RWK, Lo DYM
Prenatal Diag 2013;33(7): 675 - 681
Noninvasive Prenatal Determination of Twin Zygosity by Maternal Plasma DNA Analysis.
Qu JZZ, Leung TY (co-1st author), Jiang P, Liao GJW, Cheng YKY, Sun H, Chiu RWK, Chan KCA, Lo YM.
Clin Chem 2013; 59:427-35.
Identification of Submicroscopic Chromosomal Aberrations in Fetuses with increased Nuchal Translucency and Apparently Normal Karyotype.
Leung TY, Vogel I, Lau TK, Chong WS, Hyett JA, Petersen OB, Choy KW
Ultrasound Obst Gyn 2011;38(3): 314 - 319
Non-Invasive Prenatal Assessment of Trisomy 21 by Multiplexed Maternal Plasma DNA Sequencing : Large Scale Validity Study.
Chiu RWK, Akolekar R, Zheng YWL, Leung TY, Sun H, Chan AKC, Lun FMF, Go ATJI, Lau ET, To WWK, Leung WC, Tang RYK, Au Yeung KC, Lam H, Kung YY, Zhang XQ, Van Vugt JMG, Minekawa R, Tang MHY, Wang J, Oudejans CBM, Lau TK, Nicolaides KH, Lo DYM
Brit Med J 2011;342: c7401
Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus.
Lo DYM, Chan AKC, Sun H, Chen EZ, Jiang PY, Lun FMF, Zheng YWL, Leung TY, Lau TK, Cantor CR, Chiu RWK
Sci Transl Med 2010;2(61): 61ra91
Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma.
Chiu Rossa WK, Chan AKC, Gao Y, Lau VYM, Zheng W, Leung TY, Foo CHF, Xie B, Tsui NBY, Lun FMF, Zee BCY, Lau TK, Cantor CR, Lo DYM
Proc Natl Acad Sci USA 2008;105(51): 20458 - 20463
Cerclage Pessary for Preventing Preterm Birth in Women with a Singleton Pregnancy and a Short Cervix at 20 to 24 Weeks: A Randomized Controlled Trial.
Hui ASY, Chor MCM, Lau TK, Lao TTH, Leung TY
AM J Perinatol 2013;30(4): 283 - 288
Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma.
Chim SSC, Lee WS, Ting YH, Chan OK, Lee SWY, Leung TY
PLos ONE 2012;7(4): e34328
Cervical length at 18 - 22 weeks of gestation for prediction of spontaneous preterm delivery in Hong Kong Chinese women.
Leung TN, Pang MW, Leung TY, Poon CF, Wong SM, Lau TK
Ultrasound Obst Gyn 2005;26(7): 713 - 717
Risk and Prediction of Preterm Delivery in Pregnancies Complicated by Antepartum Hemorrhage of Unknown Origin before 34 Weeks.
Leung TY, Chan LW, Tam WH, Leung TN, Lau TK
Gynecol Obstet Inves 2001;52(4): 227 - 231
A strategy for identifying circulating placental RNA markers for fetal growth assessment.
Pang WWI, Tsui MHY, Sahota DS, Leung TY, Lau TK, Lo DYM, Chiu Rossa WK
Prenatal Diag 2009;29(5): 495 - 504
Which Ultrasound or Biochemical Markers are Independent Predictors of Small-for-Gestational Age?
Law LW, Leung TY, Sahota DS, Chan LW, Fung TY, Lau TK
Ultrasound Obst Gyn 2009;34(3): 283 - 287
Prediction of birth weight by fetal crown-rump length and maternal serum levels of pregnancy-associated plasma protein-A in the first trimester.
Leung TY, Sahota DS, Chan LW, Law LW, Fung TY, Leung TN, Lau TK
Ultrasound Obst Gyn 2008;31(1): 10 - 14
First-trimester maternal serum levels of placental hormones are independent predictors of second-trimester fetal growth parameters.
Leung TY, Chan LW, Leung TN, Fung TY, Sahota DS, Lau TK
Ultrasound Obst Gyn 2006;27(2): 156 - 161
Radiofrequency Ablation for Selective Reduction in Complicated Monochorionic Multiple Pregnancies.
Lu J, Ting YH, Law KM, Lau TK, Leung TY
Fetal Diagn Ther 2013;34(4): 211 - 216
Intrapleural Injection of OK-432 as the Primary In-utero Treatment for Fetal Chylothorax.
Leung VKT, Suen SSH, Ting YH, Law LW, Lau TK, Leung TY
Hong Kong Med J 2012;18(2): 156 - 159
Fetoscopic Laser Photocoagulation in the Management of Twin-Twin Transfusion Syndrome: Local Experience from Hong Kong.
Yang X, Leung TY, Ngan Kee WD, Chen M, Chan LW, Lau TK
Hong Kong Med J 2010;16(4): 275 - 281
Prenatal embolisation of a large chorioangioma using enbucrilate.
Lau TK, Yu SCH, Leung TY, To KF, Fung TY, Leung TN
BJOG 2005;112(7): 1002 - 1004