The Chinese University of Hong Kong & Prince of Wales Hospital

Department of Obstetrics and Gynaecology

Dr. Tang Tao Research Fellow
(852) 3505 2580 tangtao@cuhk.edu.hk

Qualifications

PhD (2008)

Dr. TANG Tao got his PhD in Dept of. O&G of the Chinese University of Hong Kong in 2008. He worked as Research Assistant Professor from 2013 and his current research interests mainly focused on Cervical cancer, RNAi based therapy strategy in cancer and Postmenopausal osteoporosis.

Research Interest:

Cervical cancer; RNAi based therapy strategy in cancer and Postmenopausal osteoporosis

Summary of research output:

  • Total publication: 11
  • H-index 6
1
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T Front Endocrinol (Lausanne). 2022 Mar 18;13:781149
2
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome Deng Y, Li H, Song Y, Cen J, Zhang Y, Sui Y, Cui D, Li TC, Xu Y, Wang CC, Chung PWJ, Tang T Front Endocrinol (Lausanne). 2022 Mar 18;13:781149
3
Transdermal Delivery of Adipocyte Phospholipase A2 siRNA using Microneedles to Treat Thyroid Associated Ophthalmopathy-Related Proptosis Liu G, Deng Y, Song Y, Sui Y, Cen J, Shao Z, Li H, Tang T Cell Transplantation 2021 Apr; 30: 1-8
4
Phage display screening identifies a prostate specific antigen (PSA)-/lo prostate cancer cell specific peptide to retard castration resistance of prostate cancer Sui Y, Zhu R, Hu W, Zhang W, Zhu H, Gong M, Gao L, Cao T, Tang T, Bo Y, Yang T Transl Oncol. 2021 Mar;14(3):101020
5
Novel genetic variants of PPARγ2 promoter in gestational diabetes mellitus and its molecular regulation in adipogenesis Wu L, Song Y, Zhang Y, Liang B, Deng Y, Tang T, Ye YC, Hou HY, Wang CC Front Endocrinol. 2021 Jan 22, 11:499788
6
Roles of NANOGP8 in cancer metastasis and cancer stem cell invasion during development of castration-resistant prostate cancer Sui Y, Zhang W, Zhu R, Gao L, Cao T, Chen C, Gong M, Zhu H, Tang T, Yu Bo Yang T Ann Transl Med. 2021 Jan;9(1):45
7
5mC profiling characterized TET2 as an anti-adipogenic demethylase Hou Y, Zhang Z, Wang Y, Gao T, Liu X, Tang T, Du Q Gene. 2020 Apr 5;733:144265
8
Insulin-like growth factor-II overexpression accelerates parthenogenetic stem cell differentiation into cardiomyocytes and improves cardiac function after acute myocardial infarction in mice Sui Y, Zhang W, Tang T, Gao L, Cao T, Zhu H, You Q, Yu B, Yang T Stem Cell Res Ther. 2020 Feb 26;11(1):86 (17 pages)
9
Specifcity profling of CRISPR system reveals greatly enhanced of-target gene editing Wang Y, Wang M, Zheng T, Hou Y, Zhang P, Tang T, Wei J, Du Q Sci Rep. 2020 Feb 10;10(1):2269
10
The high-risk HPV oncogene E7 upregulates miR-182 expression through the TGF-β/Smad pathway in cervical cancer Chen J, Deng Y, Ao L, Song Y, Xu Y, Wang CC, Choy KW, Chung TKH, Du Q, Sui Y, Yang T, Yang J, Li H, Zou C, Tang T Cancer Lett. 2019 Sep 24;460:75-85
11
Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer Dong PX, Xiong Y, Yu JH, Chen L, Tang T, Song Y, Hanley SJB, Yue JM, Watari H, Sakuragi N Oncogene. 2018 Sep; 37(39): 5257-5268
12
Linc-ROR Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Functioning as a Competing Endogenous RNA for miR-138 and miR-145 Feng L, Shi L, Lu YF, Wang B, Tang T, Fu WM, He W, Li G, Zhang JF Mol Ther Nucleic Acids. 2018 Jun 1;11:345-353
13
Bioinformatics and Microarray Analysis of miRNAs in Aged Female Mice Model Implied New Molecular Mechanisms for Impaired Fracture Healing. He B, Zhang ZK, Liu J, He YX, Tang T, Li J, Guo BS, Lu AP, Zhang BT, Zhang G Int J Mol Sci Aug 2016;17(8): E1260
14
Local Administration of siRNA through Microneedle: Optimization, Bio-distribution, Tumor Suppression and Toxicity. Tang T, Deng Y, Chen J, Zhao Y, Yue RF, Choy KW, Wang CC, Du Q, Xu Y, Han L, Chung TKH Sci Rep Jul 2016;6 (30430): 1 - 8
15
Maternal Somatic Mosaicism of FOXF1 Mutation Causes Recurrent Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins in Siblings. Luk HM, Tang T, Choy KW, Tong TMF, Wong OK, Lo FM Am J Med Genet Part A Jul 2016;170(7): 1942 - 1944
16
Transdermal Delivery of siRNA through Microneedle Array. Deng Y, Chen J, Zhao Yi, Yan X, Zhang L, Choy KW, Hu J, Sant HJ, Gale BK, Tang T Sci Rep Feb 2016;6 (21422): 1 - 8
17
Inter-molecular β-sheet Structure Facilitates Lung-targeting siRNA Delivery. Zhou J, Li D, Wen H, Zheng S, Su C, Yi F, Wang J, Liang Z, Tang T, Zhou D, Zhang L, Liang D, Du Q Sci Rep 2016;622(731): 1 - 10
18
Blockage of Src by Specific siRNA as a Novel Therapeutic Strategy to Prevent Destructive Repair in Steroid-Associated Osteonecrosis in Rabbits. Zheng L, Cao H, Chen S, Tang T, Fu W, Huang L, Chow DHK, Wang Y, Griffith JF, He W, Zhou H, Zhao D, Zhang G, Wang X, Qin L J Bone Miner Res 2015;30(11): 2044 - 2057
19
Magnetite Nanostructured Porous Hollow Helical Microswimmers for Targeted Delivery. Yan X, Zhou Q, Yu J, Xu T, Deng Y, Tang T, Feng Q, Bian L, Zhang Y, Ferreira A, Zhang L Adv Funct Mater 2015;25(33): 5333 - 5342
20
Nanocomposite-strengthened Dissolving Microneedles for Improved Transdermal Delivery to Human Skin. Yan L, Raphael AP, Zhu X, Wang B, Chen W, Tang T, Deng Y, Sant HJ, Zhu G, Choy KW, Gale BK, Prow TW, Chen X Adv Healthc Mater 2014;3(4): 555 - 564
21
Therapeutic Potentials of Gene Silencing by RNA Interference: Principles, Challenges, and New Strategies. Deng Y, Wang CC, Choy KW, Du Q, Chen J, Wang Q, Li L, Chung TKH, Tang T Gene 2014;538: 217 - 227
22
MicroRNA-182 Plays an Onco-miRNA Role in Cervical Cancer. Tang T, Wong HK, Gu W, Yu MMY, To KF, Wang CC, Wong YF, Cheung TH, Chung TKH, Choy KW Gynecol Oncol 2013;129(1): 199 - 208
23
Authentication of nasopharyngeal carcinoma tumor lines. Chan SYY, Choy KW, Tsao GSW, Tao Q, Tang T, Chung GTY, Lo KW Int J Cancer 2008;122(9): 2169 - 2171