2017.12.5
Prof. Kam Bo Wong and his research team. (From Left) Yap Shing Nim, Kam Bo Wong, Man Hon Yuen, and Yu Hang Fong
A research team led by Prof. Kam-Bo Wong, Director and Professor of the School of Life Sciences at The Chinese University of Hong Kong (CUHK), has recently released its research results which show how a Helicobacter pylori (H. pylori) can survive in the human stomach by using a toxic metal, nickel ions, to activate an enzyme that can neutralize gastric acid. This discovery helps the future development of novel drugs against H. pylori infection. The team’s research findings were published today (5 Dec) in the Proceedings of the National Academy of Sciences of the USA, a prestigious international scientific journal. (extracted from CUHK press release)
Original Article: “Structural insights into how GTP-dependent conformational changes in a metallochaperone UreG facilitate urease maturation” (2017) Proc. Natl. Acad. Sci. USA http://www.pnas.org/cgi/doi/10.1073/pnas.1712658114
About Prof. Kam-Bo Wong
Prof. Kam-Bo Wong is the Director of the School of Life Sciences at CUHK, and the deputy director of the Centre for Protein Science and Crystallography at CUHK. He is also member of State Key Laboratory of Agrobiotechnology.
Read more: CUHK Press Release