Choh-Ming Li Professor of Orthopaedics and Traumatology 卓敏矯形外科及創傷學教授
Director of CUHU SZ-HK Innovation Technology Research Institute (Futian) 香港中文大學深港創新研究院(福田)院長
Assistant Dean (Mainland Affairs), Faculty of Medicine
中大醫學院助理院長(內地事務)
Professor and Director of Musculoskeletal Research Laboratory
矯形外科及創傷學系教授兼實驗室主任
Director of Innovative Orthopaedic Biomaterials and Drug Translational Research Laboratory of Li Ka Shing Institute of Health Sciences
醫學院骨科創新生物材料和藥物轉化醫學中心主任
BIOGRAPHY
Professor Qin is Professor and Director of Musculoskeletal Research Laboratory in the Department of Orthopaedics & Traumatology, the Chinese University of Hong Kong (http://www.ort.cuhk.edu.hk). Professor Qin also holds joint professorship in Shenzhen Institutes of Advance Technology (SIAT) of Chinese Academy of Sciences (CAS) and serves Director of the Translational Medicine Research & Development Center of Institute of Biomedical & Health Engineering of SIAT (http://www.siat.cas.cn). He received his BA and M.Phil. in basic medical and life sciences in physical education at the Beijing Sports University in China, and his PhD from German Sports University, Cologne, Germany and postdoctoral training in AO-Research Institute, Davos, Switzerland. Professor Qin was research scientist in the Department of Trauma & Reconstructive Surgery, University Clinic Rudolf Virchow, Charite Medical University in Germany before joining CUHK in late 1994.
Professor Qin is the past President of the International Chinese Musculoskeletal Research Society (ICMRS) (http://www.icmrs.net) and member of a number of journal editorial boards, including Editor-in-chief of Journal of Orthopaedic Translation (http://www.e-jot.com)and editorial board member of International Journal of Sports Medicine (http://www.thieme.de/sportsmed). He holds memberships in several international and national orthopaedic and related research organizations, including college fellow of American Institute of Medical and Biological Engineering (AIMBE) (http://www.aimbe.org). He has received over 40 Research Awards and holds 30 innovation or new utility patents from PR China and USA.
Professor Qin published 10 monographs as editor or associate editor, 5 conference proceedings, 80 book chapters, and over 460 journal papers in English, German, and Chinese, including around 380 SCI articles published in Nat Med, Nat Comm, ARD, JBMR, Osteoporosis Int, Bone, A&R, Biomaterials, Acta Biomaterialia, Am J Sports Med, Int J Sports Med, etc. with citation >13000 and a H-index of 56.
EXPERTISE
Advanced Diagnosis, Prevention and Treatment of Bone Metabolic Disorders, especially Osteoporosis and Osteonecrosis, and Healing Enhancement of Musculoskeletal Injuries, in Collaboration with Research and Clinical Scientists in Medicine, Geriatrics, Rheumatologists, Traditional Medicine, and Biomaterials
Musculoskeletal Imaging, especially in Bone Densitometry, Histomorphometry and Skeletal Biomechanics
SPECIALISED RESEARCH AREAS
Musculoskeletal Disorders, including Osteoporosis, Osteonecrosis and Osteoarthritis
Musculoskeletal Injury and Repair, including Fracture and Tendon-Bone Insertion Repair
Innovation, Research and Development of Biodegradable Metals for Orthopaedic Applications
Qin L*, Genant HK, Griffith J, Leung KS (eds). Advanced Bioimaging Technologies in Assessment of Quality of Bone and Scaffold Biomaterials. Springer Verlag, 2007.
2.
Leung KS, Qin YX, Cheung WH, Qin L*. (2008) A Practical Manual for Musculoskeletal Research. World Scientific, 2008.
3.
秦嶺(主編)*:骨內科學 人民衛生出版社, 2013 (Qin L*(Ed) Orthopaedic Medicine (in Chinese). Peoples' Medical Publishing House, 2013
Yao H, Xu JK, Wang JL, Zhang YF, Zheng NY, Yue J, Mi J, Zheng LZ, Dao BY, Huang WH, Yung SH, Hu PJ, Ruan YC, Xue QY, Ho KW, Qin L*. Combination of magnesium ions and Vitamin C alleviates synovitis and osteophyte formation in osteoarthritis of mice. Bioactive Materials, 6:1341-1352, 2021.
2.
Wang JL, Xu JK, Hopkins C, Chow DH, Qin L*. Biodegradable Magnesium-Based Implants in Orthopedics-A General Review and Perspectives. Advanced Science, 7(8):1902443, 2020.
3.
Tong WX, Zeng YL, Chow HK, Yeung W, Xu JK, Deng YJ, Chen SH, Zhao H, Zhang XL, Ho KW, QinL*, Mak KL. Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade. Annals of the Rheumatic Diseases, 78:551-561, 2019.
4.
Feng Q, Xu JK, Zhang KY, Yao H, Zheng NY, Zheng LZ, Wang JL, Wei KC, Xiao XF, Qin L*, Bian LM. Dynamic and cell-infiltratable hydrogels as injectable carrier of therapeutic cells and drugs for treating challenging bone defects. ACS Central Science, 5:440-450, 2019.
5.
Huang L, Wang XL, Cao HJ, Li L, Chow HW, Tian L, Wu H, Zhang JY, Wang N, Zheng LZ, Yao XS, Yang ZJ, Qin L*. A bone-targeting delivery system carrying osteogenic phytomolecule icaritin prevents osteoporosis in mice. Biomaterials, 182:58-72, 2018.
6.
Wang J, Xu J, Song B, Chow DH, Shu-Hang Yung P, Qin L*. Magnesium (Mg) based interference screws developed for promoting tendon graft incorporation in bone tunnel in rabbits. Acta Biomaterialia 63:393-410, 2017.
7.
Zhang Y, Xu J, Ruan YC, Yu MK, O'Laughlin M, Wise H, Chen D, Tian L, Shi D, Wang J, Chen S, Feng JQ, Chow DH, Xie X, Zheng L, Huang L, Huang S, Leung K, Lu N, Zhao L, Li H, Zhao D, Guo X, Chan K, Witte F, Chan HC, Zheng Y, Qin L*. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine, 22(10):1160-1169, 2016.
8.
Wang JL, Witte F, Xi TF, Zhang YF, Yang K, Yang YS, Zhao DW, Meng J, Li YD, Li WR, Chan KM, Qin L*. Recommendation for modifying current cytotoxicity testing standards for biodegradable magnesium-based materials. Acta Biomaterialia 21:237-49, 2015.
9.
Qin L*, Yao D, Zheng LZ, Liu WC, Liu Z, Lei M, Huang L, Xie XH, Wang XL, Chen Y, Yao XS, Peng J, Gong H, Griffith JF, Huang YP, Zheng YP, Feng JQ, Liu Y, Chen SH, Xiao DM, Wang DP, Xiong JY, Pei DQ, Zhang P, Pan XH, Wang XH, Lee KM, CY Cheng. Phytomolecule Icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits. Biomaterials 59: 125-43, 2015.
10.
Zhang G, Guo BS, Wu H, Tang T, Zhang BT, Zheng LZ, He YX, Yang ZJ, Pan XH, Chow HL, To KW, Li YP, Li DH, Wang XL,Wang YX, Lee KM, Hou ZB, Dong N, Li G, Leung KS, Hung LK, He FC, Zhang LQ, Qin L*. A delivery system targeting bone formation surface to facilitate RNAi-based bone anabolic therapy. Nature Medicine 18(2):307-14, 2012.