Professor WONG Kwok Chu George    
黃國柱

Professor
MB ChB (CUHK), MD (CUHK), FRCSEd (SN), FCSHK, FHKAM (Surgery)

Neurosurgery
(852) 3505 2624
georgewongadd this for spam@add this for spamsurgery.cuhk.edu.hk
L-4344-2016

Biography

Experienced Neurosurgeon and Neuro-interventionist with a demonstrated history of working in the hospital & health care industry and skilled in Clinical and Translational Research, Debriefing, Medical Education, Sedation and Communication Workshops, Certified Healthcare Simulation Educator (CHSE), Medical Devices, and Medicine. Mediation with training from HKU Intensive Mediation Course / Accord Group programme and HKU Family Mediation Module. Arbitration professional with a Master of Laws - LLM focused in Arbitration and Dispute Resolution from The University of Hong Kong and a Fellow member of the Chartered Institute of Arbitrators FCIArb.

Scopus: https://www.scopus.com/authid/detail.uri?authorId=13605133200
ResearchGate: https://www.researchgate.net/profile/George-Wong-2

Research Interests

• Subarachnoid Haemorrhage
• Intracranial Aneurysm
• Brain Tumour
• Brain Injury Outcome Research
• Translational Stroke Research

Additional Information

Specialization:

• Neuro-endovascular intervention
• Neurosurgery

Award and Honour:

• GB Ong Travelling Fellowship (2007)
• Royal College of Surgeons of Edinburgh Syme Medal (2011)
• State Scientific and Technological Progress Award Second-class Award (2011)
• World Federation of Neurological Surgeons Young Neurosurgeon Award (2013)
• American College of Surgeons Centennial Scholar (2013)
• American College of Surgeons Elias Hanna Scholar (2013)
• Sir Robert Black Trust Fund Scholar and Harvard MGH Athinoula A. Martinos Center for Biomedical Imaging fMRI Visiting Fellowship (2013)
• Chinese National Medical Association Science and Technology Award (2014)
• Boston Center for Medical Simulation Scholar (2015)
• American Heart Association Paul Dudley White International Scholar (2019)
• Fellow of the American Heart Association (2019)
• Fellow of the European Stroke Organization (2020)

Others:

1. Honorary Appointment:
   
   • Consultant (Honorary), NTEC, Hospital Authority
2. Editorship:
   
   • Neurointervention (Korean Society of Interventional Neuroradiology)
   • Journal of Japanese Medical Association
   • Frontiers in Surgery (Neurosurgery)
3. Professional Service:
   
   • Deputy Director of the Hong Kong Jockey Club Innovative Learning Centre for Medicine
   • Chairman, Education Subcommittee of the HKJC Innovative Learning Centre for Medicine, Workplace Based Assessment Course, OSCE Workshop
   • Chairmen, HST and Fellow Education Subcommittee, Procedural Sedation Course, Workplace Based Assessment Working Group, & Simulation Education Working Group, the College of Surgeons of Hong Kong
   • Members, Professionalism and Ethics Committee & Task Forces on Law for Healthcare Practitioners, Disclosure Apology Alternative Dispute Resolution, eHKAM, Hong Kong Academy of Medicine
   • Chairperson, Advancing Neurosurgery Through Audit (ANTA) Programme of the COC(Neurosurgery) and Hospital Authority
   • Council member of the Asian Australasian Federation of Interventional and Therapeutic Neuroradiology
   • Steering committee member (Unruptured Cerebral Aneurysms and Subarachnoid Hemorrhage) of US National Library of Medicine and National Institute of Neurological Disorders and Stroke Common Data Elements
   • President of the Hong Kong Society of Simulation in Healthcare (2022-2023)
   • Vice President of the Hong Kong Society of Interventional and Therapeutic Neuroradiology (2022-2024)
   • Certified Healthcare Simulation Educator, Society of Simulation in Healthcare
   • Fellow of the International Society for Quality in Healthcare
   • Fellow of the Chartered Institute of Arbitrators
4. Academic Engagement:
   
   • Module coordinator of Neurosurgery CUHK MB ChB program
   • Undergraduate programs
   • Taught master programs
   • Research postgraduate supervision (MPhil, PhD)

Selected Publications

1. Chen J, Sun L, Lyu H, Zheng Z, Lai H, Wang Y, Luo Y, Lu G, Chan WY, Guan S, Zhang Y, Chen X, Li Z, Ko H, Wong KCG*. Single-cell analysis of microglial transcriptomic diversity in subarachnoid haemorrhage. Clin Transl Med. 2022 Apr;12(4):e783. doi: 10.1002/ctm2.783.
2. Yan J, Chen J, Chen J, Yan W, Ding Q, Yan K, Du J, Lam CP, Wong GKC, Cheng SS. A Continuum Robotic Cannula with Tip Following Capability and Distal Dexterity for Intracerebral Hemorrhage Evacuation. IEEE Trans Biomed Eng. 2022 Mar 11;PP. doi: 10.1109/TBME.2022.3158539.
3. Chan HSC, Ng HK, Chan AK, Cheng SH, Chow C, Wong N, Wong GKC*. Establishment and characterization of meningioma patient-derived organoid. J Clin Neurosci. 2021 Dec;94:192-199. doi: 10.1016/j.jocn.2021.10.035.
4. Zheng ZV, Chen J, Lyu H, Lam SYE, Lu G, Chan WY, Wong GKC*. Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage. Stroke Vasc Neurol. 2022 Feb;7(1):62-70. doi: 10.1136/svn-2021-001028.
5. Zheng ZY, Lu G, Xiong ZQ, Leung CK, Su XW, Li T, Poon WS, Chan WY, Wong GKC*. Integrated analysis of gait parameters and gene expression profiles in a murine model of subarachnoid hemorrhage. Genes Brain Behav. 2021 Jun;20(5):e12728. doi: 10.1111/gbb.12728.
6. Zheng ZV, Lyu H, Lam SYE, Lam PK, Poon WS, Wong GKC*. The Dynamics of Microglial Polarization Reveal the Resident Neuroinflammatory Responses After Subarachnoid Hemorrhage. Transl Stroke Res. 2020 Jun;11(3):433-449. doi: 10.1007/s12975-019-00728-5.
7. Chan MTH, Wong JYY, Leung AKT, Lu G, Poon WS, Lau AY, Chan WY, Wong GK*. Plasma and CSF miRNA dysregulations in subarachnoid hemorrhage reveal clinical courses and underlying pathways. J Clin Neurosci. 2019 Apr;62:155-161.
8. Lu G, Wong MS, Xiong MZQ, Leung CK, Su XW, Zhou JY, Poon WS, Zheng VZY, Chan WY, Wong GK*. Circulating MicroRNAs in Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage. J Am Heart Assoc. 2017 Apr 25; 6(4). pii: e005363. doi: 10.1161/JAHA.116.005363.
9. Su XW, Chan AH, Lu G, Lin M, Sze J, Zhou JY, Poon WS, Liu Q, Zheng VZ, Wong GK*. Circulating microRNA 132-3p and 324-3p Profiles in Patients after Acute Aneurysmal Subarachnoid Hemorrhage. PLoS One. 2015; 10(12):e0144724.
10. Wong GK*, Nung RC, Sitt JC, Mok VC, Wong A, Ho FL, Poon WS, Wang D, Abrigo J, Siu DY. Location, Infarct Load, and 3-Month Outcomes of Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage. Stroke. 2015 ;46(11):3099-104.
11. Wong GK*, Chan DY, Siu DY, Zee BC, Poon WS, Chan MT, Gin T, Leung M, HDS-SAH Investigators. High dose simvastatin for aneurysmal subarachnoid hemorrhage. Stroke 2015; 46:382-388.
12. Wong GK*, Lam SW, Ngai K, Wong A, Poon WS, Mok V, Cognitive Dysfunction after Aneurysmal Subarachnoid Haemorrhage Investigators. Cognitive domain deficits in patients with aneurysmal subarachnoid haemorrhage at 1 year. J Neurol Neurosurg Psychiatry. 2013; 84:1054-1058.
13. Wong GK*, Yeung DK, Ahuja AT, King AD, Lam CW, Chan MT, Gin T, Poon WS. Intracellular free magnesium of brain and cerebral phosphorus-containing metabolites after subarachnoid hemorrhage and hypermagnesemic treatment: a ^³¹P–magnetic resonance spectroscopy study. Clinical article. J Neurosurg. 2010;113(4):763-9.
14. Wong GK*, Poon WS, Boet R, Chan MT, Gin T, Zee B. Plasma magnesium concentrations and clinical outcomes in aneurysmal subarachnoid hemorrhage patients: post-hoc analysis of Intravenous Magnesium Sulphate for Aneurysmal Subarachnoid Hemorrhage (IMASH) trial. Stroke. 2010; 41:1441-1444.
15. Wong GK, Poon WS, Chan MT, Gin T, Boet R, Zee B. Intravenous Magnesium Sulphate for Aneurysmal Subarachnoid Hemorrhage (IMASH): a randomized double-blinded placebo-controlled multicenter phase III trial. Stroke. 2010; 41:921-926.