葉兆波 博士

履歷(教育及工作經驗)

教育：

1. 1993 香港中文大學生物化學系榮譽理學學士
2. 1998 香港科技大學生物化學系哲學博士

工作經驗：

1. 1998-2000 裘槎基金會博士後研究員
2. 2001 香港中文大學中醫學院博士後研究員
3. 2002-2006 香港中文大學中醫學院科學主任
4. 2006-2009 香港中文大學中醫學院研究助理教授
5. 2009-2017 香港中文大學中醫學院研究員
6. 2017至今  香港中文大學中醫學院高級研究員

教學

1. BCME5112 Pharmacology and toxicology of Chinese Medicines, The Chinese University of Hong Kong
2. BCME4106 Tutorial in Chinese Medicine (Current Literature of Chinese Medicine and Management of Information), The Chinese University of Hong Kong
3. BCME5102 Authentication of Chinese Medicinal Materials, The Chinese University of Hong Kong
4. Certificate Programme in Authentication of Chinese Materia Medica (funded by Innovation and Technology Commission), The Chinese University of Hong Kong

科研範圍

1. 中藥藥理研究
2. 中藥標準化及質量控制
3. 中藥化學成分分析服務
4. 中成藥註冊諮詢服務

著作及論文（選列)

1. Zhao J, Niu X, Yu J, Xiao X, Li W, Zang L, Hu Z, Siu-Po Ip P, Li W. Poria cocos polysaccharides attenuated ox-LDL-induced inflammation and oxidative stress via ERK activated Nrf2/HO-1 signaling pathway and inhibited foam cell formation in VSMCs. Int Immunopharmacol 2020;80:106173. DOI:10.1016/j.intimp.2019.106173.
2. Xian YF, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX. Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3β signaling pathway. FASEB J 2019;33(9):10393-408. DOI:10.1096/fj.201802743RR.
3. Xian YF, Hu Z, Ip SP, Chen JN, Su ZR, Lai XP, Lin ZX. Comparison of the anti-inflammatory effects of Sinapis alba and Brassica juncea in mouse models of inflammation. Phytomedicine 2018;50:196-204. DOI:10.1016/j.phymed.2018.05.010.
4. Lai ZQ, Ip SP, Liao HJ, Lu Z, Xie JH, Su ZR, Chen YL, Xian YF, Leung PS, Lin ZX. Brucein D, a Naturally Occurring Tetracyclic Triterpene Quassinoid, Induces Apoptosis in Pancreatic Cancer through ROS-Associated PI3K/Akt Signaling Pathway. Front Pharmacol 2017;8:936. DOI:10.3389/fphar.2017.00936.
5. Mao QQ, Huang Z, Zhong XM, Xian YF, Ip SP*. Brain-derived neurotrophic factor signalling mediates the antidepressant-like effect of piperine in chronically stressed mice. Behav Brain Res 2014;261:140-5. DOI:10.1016/j.bbr.2013.12.020.
6. Yang JM, Xian YF, Ip PS, Wu JC, Lao L, Fong HH, Sung JJ, Berman B, Yeung JH, Che CT. Schisandra chinensis reverses visceral hypersensitivity in a neonatal-maternal separated rat model. Phytomedicine 2012;19(5):402-8. DOI:10.1016/j.phymed.2011.11.013.
7. Tjong Y, Ip S, Lao L, Fong HH, Sung JJ, Berman B, Che C. Analgesic effect of Coptis chinensis rhizomes (Coptidis Rhizoma) extract on rat model of irritable bowel syndrome. J Ethnopharmacol 2011;135(3):754-61. DOI:10.1016/j.jep.2011.04.007.
8. Ip SP, Zhao M, Xian Y, Chen M, Zong Y, Tjong YW, Tsai SH, Sung JJ, Bensoussan A, Berman B, Fong HH, Che CT. Quality assurance for Chinese herbal formulae: standardization of IBS-20, a 20-herb preparation. Chin Med 2010;5:8. DOI:10.1186/1749-8546-5-8.
9. Mao QQ, Xian YF, Ip SP*, Che CT. Involvement of serotonergic system in the antidepressant-like effect of piperine. Prog Neuropsychopharmacol Biol Psychiatry 2011;35(4):1144-7. DOI:10.1016/j.pnpbp.2011.03.017.
10. Chen Y, Ip SP*, Ko KM, Poon TC, Ng EW, Lai PB, Mao QQ, Xian YF, Che CT. A proteomic approach in investigating the hepatoprotective mechanism of Schisandrin B: role of raf kinase inhibitor protein. J Proteome Res 2011;10(1):299-304. DOI:10.1021/pr100871h.