Data 80 95 120 124 75 72 75 92 84 94 100 106 88 96 92 98

Data a single column with 1 (for prefer tmt 1) and -1 (for prefer tmt2). 0 can be used for ties but will be ignored. Click button to run program using example data, or replace example parameters and data then click button to tun. Probability of Type I Error (α)(one tail) Power (1 - β) Mean difference to detect Standard deviation of difference

MacroPlot Code

Known Variance
Armitage P. Restricted sequential procedures(1957) Biometrika 44: p 9-26.

Unknown Variance
Sneiderman MA, Armitage P. Closed sequential t test(1952) Biometrika 49:p 359-366.
S. Zhang & J. Jin "Computation of Special Functions" (Wiley, 1996), with fortran algorithm downloaded from http://jin.ece.uiuc.edu/routines/mchgm.for