Sample Size : Power : Confidence Interval : Pilot Studies :

Data Input for Sample Size Estimation is a table of 4 columns

• Each row contains data from a separate study
• Col 1 = probability of Type I error (α)
• Col 2 = power (1-β)
• Col 3 = mean of paired differences
• Col 4 = Standard Deviation of paired differences

Data Input for Power Estimation is a table of 4 columns

• Each row contains data from a separate study
• Col 1 = probability of Type I error (α)
• Col 2 = sample size (Pairs) used
• Col 3 = mean of Paired Differences observed
• Col 4 = Standard Deviation of paired differences

Data Input for Confidence Interval Estimation is a table of 3 columns

• Each row contains data from a separate study
• Col 1 = percent confidence (usually 95)
• Col 2 = sample size used (pairs)
• Col 3 = standard deviation of paired differences observed

Data Input for Pilot Study is for a single plan, a single column with 4 rows

• Row 1 : Percent Confidence required, usually 95 or 99
• Row 2 : Standard Deviation of Paired Mean
• Row 3 : Sample Size Interval
• Row 4 : Maximum sample size

Machin D, Campbell M, Fayers, P, Pinol A (1997) Sample Size Tables for Clinical Studies. Second Ed. Blackwell Science IBSN 0-86542-870-0 p. 73-74