Professor ZHANG Tao, Judy

Current Position:
Research Assistant Professor

Email:
taozhang@cuhk.edu.hk 

Qualifications:
MBBS, MMed (O&G), PhD (O&G)

Research Interests:
Reproductive Immunology (endometriosis, endometrial receptivity,
recurrent miscarriage, implantation failure, PCOS)

 

 

1Immunologic Memory in Pregnancy: Focusing on Memory Regulatory T Cells
Zhang YJ, She L, Zhang T, Muyayalo KP., Luo J, Mor G, Liao AH
Int. J. Biol. Sci. 2022 Mar; 18(6): 2406-2418
2Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2+ macrophage differentiation
Zhou WJ, Yang HL, Mei J, Chang KK, Lu H, Lai ZZ, Shi JW, Wang XH, Wu K, Zhang T, Wang J, Sun JS, Ye JF, Li DJ, Zhao JY, Jin LP, Li MQSci Adv. 2022 Feb 25;8(8):eabj2488
3Insight of Autophagy in Spontaneous Miscarriage
Qin XY, Shen HH, Zhou WJ, Mei J, Lu H, Tan XF, Zhu R, Zhou WH, Li DJ, Zhang T, Ye JF, Li MQ
Int J Biol Sci. 2022 Jan 1;18(3):1150-1170
4 Auto-immunity and endometriosis: evidence, mechanism and therapeutic potential
Zhang T, Li TC, Wang CC
In: Immunology of Endometriosis: Pathogenesis and Management
2021; Volume 2 Ch 6:85-104
5An In-Silico, In-Vitro and In-Vivo Combined approach to identify NMNATs as potential protein targets of ProEGCG for treatment of endometriosis
Hung SW, Liang B, Gao Y, Zhang R, Tan Z, Zhang T, Chung PWJ, Chan TH, Wang CC
Front Pharmacol. 2021 Oct 14;12:714790 
6Protopanaxadiol improves endometriosis associated infertility and miscarriage in sex hormones receptors-dependent and independent manners
Lai ZZ, Yang HL, Shi JW, Shen HH, Wang Y, Chang KK, Zhang T, Ye JF, Sun JS, Qiu XM, Li MQ
Int J Biol Sci. 2021 May 5;17(8):1878-1894
7The identification of endometrial immune cell densities and clustering analysis in the mid-luteal phase as predictor for pregnancy outcomes after IVF-ET treatment
Zhao Y, Man GCW, Wang J, Liu Y, Kwong J, Zhang T, Chung JPW, Wang CC, Chen X, Li TC
J Reprod Immunol. 2021 Oct 5;148:103431
8Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Zhao Y, Man GCW, Chan LKY, Guo X, Liu Y, Zhang T, Kwong J, Wang CC, Chen X, Li TC
J Vis Exp. 2021 Aug 4;(174): e62931
9Receptor tyrosine kinase inhibitor Sunitinib as novel immunotherapy to inhibit myeloid-derived suppressor cells for treatment of endometriosis
He Y, Hung SW, Liang B, Zhang RZ, Gao YT, Chu CY, Xu H, Zhang T, Chung JPW, Wang CC
Front. Immunol. 2021 July;12:641206
10Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review
Hung SW, Zhang RZ, Tan ZYR, Chung JPW, Zhang T, Wang CC
Med Res Rev. 2021 Jul;41(4):2489-2564
11Successful implantation is associated with a transient increase in serum pro-inflammatory cytokine profile, following by a switch to anti-inflammatory cytokine profile prior to confirmation of pregnancy
Zhao Y, Zhang T, Guo X, Wong CK, Chen X, Chan YL, Wang CC, Laird S, Li TC
Fertil Steril. 2021 Apr;115(4):1044-1053
12Ovarian hormones-autophagy-immunity axis in menstruation and endometriosis.
HH Shen, T Zhang, HL Yang, ZZ Lai, WJ Zhou, J Mei, JW Shi, R Zhu, FY Xu, DJ Li, JF Ye, MQ Li.
Theranostics. 2021 Jan; 11(7): 3512-3526.
13Uterine CD56+ cell density and euploid miscarriage in women with a history of recurrent miscarriage: a clinical descriptive study.
XY Chen, T Zhang, YY Liu, WC Cheung, YW Zhao, CC Wang, S Laird, TC Li.
Eur J Immunol. 2021 Sept; 51: 487-489.
14The use of multiplex staining to measure the density and clustering of four endometrial immune cells around the implantation period in women with recurrent miscarriage: comparison with fertial controls.
YW Zhao, XY Chen, T Zhang, LKY Chan, YY liu, JPW Chung, J Kwong, TC Li.
J Mol Histol. 2020 Aug; 51:593-603.
15Associstion between chronic endometritis and uterine natural killer cell density in women with recurrent miscarriage: clinical implications.
XY Chen, YY Liu, YW Zhao, WC Cheung, T Zhang, RF Qi, JPW Chung, CC Wang, TC Li.
J Obstet Gynaecol Res. 2020 Jun; 46(6): 858-863.
16Early transient suppression of immune checkpoint proteins Tim-3 and PD-1 in peripheral blood lymphocytes after blastocyst transfer is associated with successful implantation.
T Zhang, WY Zhu, YW Zhao, WC Cheun, YY Liu, XY Chen, Y Du, KT Leung, YL Chan, CC Wang, S Laird, TC Li.
Fertil and Steril. 2020 Aug;114(2):426-435.
17Effects of high progesterone in in-vitro fertilization cycle on DNA methylation and gene expression of adhesion molecules on endometrium during implantation window.
Xiong Y, Hu L, Zhang T, Wang M, Xu H, Li TC, Sun Y, Wang CC.
J Assist Reprod Genet. 2020 Jan;37(1):33-43.
18Intrauterine infusion of human chorionic gonadotropin before embryo transfer in IVF/ET cycle: the critical review.
T Zhang, XY Chen, CC Wang, TC Li, J Kim.
Am J Reprod Immunol. 2019 Feb; 81(2): e13077.
19The link between immunity, autoimmunity and endometriosis: a literature update.
T Zhang, Caterina De Carolis, GCW Man, Chi-Chiu Wang.
Autoimmunity reviews. 2018 Oct; 17(10): 945-955.
20MDSCs drive the process of endometriosis by enhancing angiogenesis and provide a new potential approach for treatment.
Zhang T, Zhou JH, Man GCW, Leung KT, Liang B, Xiao B, Ma XT, Huang SY, Huang HX, Hegde VL, Zhong Y, Li YM, Kong GWS, Yiu AKW, Kwong J, Ng PC, Lessey BA, Nagarkatti PS, Nagarkatti M, Wang CC.
Eur J Immunol. 2018 Jun; 48(6): 1059-1073.
21Successful treatment with intrauterine delivery of dexamethasone for repeated implantation failure.
Zhang T, Huang CY, Du Y, Lian RC, Mo ML, Zeng Y, Mor G.
Am J Reprod Immunol. 2017 Dec; 78(6): e12766.
22Detection of dendritic cells and related cytokines in follicular fluid of patients with polycystic ovary syndrome.
Zhang T, Tian F, Huo R, Tang A, Zeng Y, Duan YG.
Am J Reprod Immunol. 2017 Sep; 78(3): e12717.
23Efficacy of intrauterine perfusion of granulocyte colony-stimulating factor (G-CSF) for infertile women with thin endometrium: A systematic review and meta-analysis.
Xie YR, Zhang T, Tian ZP, Zhang JM, Wang WX, Zhang H, Zeng Y, Ou JP, Yang YH.
Am J Reprod Immunol. 2017 Aug; 78(2): e12701.
24The regulations and role of circadian clock and melatonin in uterine receptivity and pregnancy-An immunological perspective.
Man GCW, Zhang T, Chen X, Wang J, Wu F, Liu Y, Wang CC, Cheong Y, Li TC.
Am J Reprod Immunol. 2017 Aug; 78(2): e12715.
25Human chorionic gonadotropin potentially affects pregnancy outcome in women with recurrent implantation failure by regulating the homing preference of regulatory cells.
Diao LH, Li GG, Zhu YC, Tu WW, Huang CY, Lian RC, Chen X, Li YY, Zhang T, Huang Y, Zeng Y.
Am J Reprod Immunol. 2017 Mar; 77(3): e12618.
26Modulatory effects of vitamin D on peripheral cellular immunity in patients with recurrent miscarriage.
Chen X, Yin B, Lian RC, Zhang T, Zhang HZ, Diao LH, Li YY, Huang CY, Liang DS, Zeng Y.
Am J Reprod Immunol. 2016 Dec, 76(6): 432-438.
27Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis.
Xu H, Zhang T, Man GCW, May KE, Becker CM, Davis TN, Kung AL, Birsner AE, D’Amato RJ, Wong AW, Wang CC.
Angiogenesis 2013 Jul; 16: 541-551.
28Prodrug of green tea epigallocatchin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice.
Wang CC, Xu H, Man GCW, Zhang T, Chu KO, Chu CY, Cheng JT, Li G, He YX, Qin L, Lau TS, Kwong J, Chan TH.
Angiogenesis 2013 Aug; 16(1): 59-69.