Medical Retina and Uveitis Fellowship Programme

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  4. Medical Retina and Uveitis Fellowship Programme

Dr Mårten E BRELÉN

Director

Dr Carmen KM CHAN

Faculty

Dr TSANG Chi Wai

Faculty

Dr Angie HC FONG

Faculty  

Dr MOHAMED, Shaheeda

Faculty

Dr Danny SC NG

Faculty

Dr Guy LJ CHEN

Faculty

Dr LI Chi Lai

Faculty  

Introduction

The Medical Retina and Uveitis Service at the Hong Kong Eye Hospital provides high quality subspecialty care in the diagnosis and treatment of Medical Retina diseases and Uveitis for patients in Hong Kong. Our clinic serves more than 100 patients every week. Besides providing high quality patient care, the Medical Retina and Uveitis service has a strong track record in research. During the fellowship, fellows will actively participate in all clinical services and various research projects.

Clinical Attachment for Medical Retina and Uveitis

  • 3 outpatient clinics per week including Medical Retina Clinic, Uveitis Clinic, and Diabetic Macular Edema clinic
  • 1 session of electrophysiology per week
  • 1 session of intravitreal injections and photodynamic therapy per week
  • 2 sessions of laser clinic per month

Ongoing Research Activities in Medical Retina and Uveitis

  • Genetic studies in age-related macular degeneration, hereditary retinal diseases and Uveitis
  • Pharmacological treatment for age-related macular degeneration, diabetic macular edema and other retinal diseases including anti-VEGF and photodynamic therapy
  • Clinical application of visual electrophysiology including multifocal ERG, full-field ERG, pattern ERG, and VEP
  • Evaluation of macular diseases with fluorescein angiography, indocyanine green angiography and optical coherence tomography

Recent Representative Publications

  1. Huang H, Guan C, Ng DS, Liu X, Chen H. Macular Pigment Optical Density Measured by a Single Wavelength Reflection Photometry with and without Mydriasis. Curr Eye Res. 2019 Mar;44(3):324-328. (Impact Factor: 2.120) [https://www.ncbi.nlm.nih.gov/pubmed/30376638]
  2. Szeto SKH, Wong R, Lok J, Tang F, Sun Z, Tso T, Lam TCH, Tham CC, Ng DS, Cheung CY. Non-mydriatic ultrawide field scanning laser ophthalmoscopy compared with dilated fundal examination for assessment of diabetic retinopathy and diabetic macular oedema in Chinese individuals with diabetes mellitus. Br J Ophthalmol. 2018 Oct 31. pii: bjophthalmol-2018-311924. (Impact Factor: 3.384) [https://www.ncbi.nlm.nih.gov/pubmed/30381391]
  3. Yim CL, Tam M, Chan HL, Tang SM, Au SCL, Yip WWK, Ko STC, Rong SS, Chen LJ, Ng DS, Yam JCS. Association of antenatal steroid and risk of retinopathy of prematurity: a systematic review and meta-analysis. Br J Ophthalmol. 2018 Oct;102(10):1336-1341. (Impact Factor: 3.384) [https://www.ncbi.nlm.nih.gov/pubmed/29632000]
  4. Tang F, Sun Z, Wong R, Lok J, Lam A, Tham CC, Chan CK, Mohamed S, Lam TC, Szeto SK, Ng DS, Cheung CY. Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study. Br J Ophthalmol. 2018 Jun 4. pii: bjophthalmol-2017-312010. (Impact Factor: 3.384) [https://www.ncbi.nlm.nih.gov/pubmed/29866787]
  5. Cheung CY, Tang F, Ng DS, Wong R, Lok J, Sun Z, Tso T, Lam A, Brelén M, Chong KK, Luk AO, Chan JC, Wong TY, Tham CC. The Relationship of Quantitative Retinal Capillary Network to Kidney Function in Type 2 Diabetes. Am J Kidney Dis. 2018 Jun;71(6):916-918. (Impact Factor: 7.543) [https://www.ncbi.nlm.nih.gov/pubmed/29501263]
  6. Mak CY, Sin HP, Ho M, Chan VC, Young AL, Brelen ME. Bilateral acute retinal necrosis after bilateral cataract surgery in an immunocompromised patient: a case report. Int Ophthalmol. 2018 Jun;38(3):1329-1332. (Impact Factor: 1.335) [https://www.ncbi.nlm.nih.gov/pubmed/28536762]
  7. Ng DS, Sun Z, Young AL, Ko ST, Lok JK, Lai TY, Sikder S, Tham CC. Impact of virtual reality simulation on learning barriers of phacoemulsification perceived by residents. Clin Ophthalmol. 2018 May 11;12:885-893. [https://www.ncbi.nlm.nih.gov/pubmed/29785084]
  8. Bakthavatchalam M, Lai FHP, Rong SS, Ng DS, Brelen ME. Treatment of cystoid macular edema secondary to retinitis pigmentosa: a systematic review. Surv Ophthalmol. 2018 May – Jun;63(3):329-339. (Impact Factor: 3.764) [https://www.ncbi.nlm.nih.gov/pubmed/28987613]
  9. Ng DSC, Lai TYY, Cheung CMG, Ohno-Matsui K. Anti-Vascular Endothelial Growth Factor Therapy for Myopic Choroidal Neovascularization. Asia Pac J Ophthalmol (Phila). 2017 Nov-Dec;6(6):554-560. [https://www.ncbi.nlm.nih.gov/pubmed/29057641]
  10. Lu X, Chen W, Xia H, Zheng K, Jin C, Ng DSC, Chen H. Atrophy of retinal inner layers is associated with poor vision after endophthalmitis: a spectral domain optical coherence tomography study
    Eye (Lond). 2017 Oct;31(10):1488-1495. (Impact Factor: 2.275) [https://www.ncbi.nlm.nih.gov/pubmed/28574491]
  11. Bakthavatsalam M, Ng DS, Lai FH, Tang FY, Brelén ME, Tsang CW, Lai TY, Cheung CY. Choroidal structures in polypoidal choroidal vasculopathy, neovascular age-related maculopathy, and healthy eyes determined by binarization of swept source optical coherence tomographic images.
    Graefes Arch Clin Exp Ophthalmol. 2017 May;255(5):935-943. (Impact Factor: 1.991) [https://www.ncbi.nlm.nih.gov/pubmed/28150038]
  12. Ng DS, Yip YW, Bakthavatsalam M, Chen LJ, Ng TK, Lai TY, Pang CP, Brelén ME. Elevated angiopoietin 2 in aqueous of patients with neovascular age related macular degeneration correlates with disease severity at presentation. Sci Rep. 2017 Mar 27;7:45081. (Impact Factor: 5.228) [https://www.ncbi.nlm.nih.gov/pubmed/28345626]
  13. Ng DS, Bakthavatsalam M, Lai FH, Cheung CY, Cheung GC, Tang FY, Tsang CW, Lai TY, Wong TY, Brelén ME. Classification of Exudative Age-Related Macular Degeneration With Pachyvessels on En Face Swept-Source Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1054-1062. (Impact Factor: 3.427) [https://www.ncbi.nlm.nih.gov/pubmed/28195603]
  14. Ke Liu, Li Ma, Timothy Y.Y. Lai, Marten E. Brelen, Pancy O.S. Tam, Cement C. Tham, Chi Pui Pang, Li Jia Chen. Evaluation of the Association of C5 with Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy. Eye and Vision 2019 Nov 7;6:34.
  15. Li Ma, Tsz Kin Ng, Haoyu Chen, Marten Brelen, Timothy Lai, Mary Ho, Pancy O.S. Tam, Alvin Young, Dr Weiqi Chen, Clement Tham, Chi Pui Pang, Li Jia Chen. Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration. Experimental Eye Research 2019 Oct;187:107748.
  16. Mary Ho, Li Jia Chen, Helena PY Sin, Lawrence PL Iu, # Marten Brelen, Assunta CH Ho, Timothy Y Y Lai, Alvin L Young. Experience of using adalimumab in treating sight-threatening paediatric or adolescent Behcet’s disease related uveitis. Journal of Ophthalmic Inflammation and Infection 2019 Jul 31;9(1):14.
  17. Caryssa L. Yan, # Mårten E. Brelén, Haoyu Chen, Weiqi Chen. Spontaneous Intrapapillary Hemorrhage With Adjacent Peripapillary Subretinal Hemorrhage In Adolescents. Cli Exp Vis Eye Res 2019, 2, 6–10.
  18. Brelén ME, Ng DS, Cheung CY. The Question of Prescribing Calcium Supplements to Patients at High Risk of Age-Related Macular Degeneration. JAMA Ophthalmol. 2019 May 1;137(5):550-551.
  19. Tang FY, Chan EO, Sun Z, Wong R, Lok J, Szeto S, Chan JC, Lam A, Tham CC, Ng DS, Cheung CY. Eye Vis (Lond). 2020 Feb 3;7:7. doi: 10.1186/s40662-019-0173-y. eCollection 2020.
  20. Yam JC, Tang SM, Kam KW, Chen LJ, Yu M, Law AK, Yip BH, Wang YM, Cheung CYL, Ng DSC, Young AL, Tham CC, Pang CP. Acta Ophthalmol. 2020 Jan 24. doi: 10.1111/aos.14350. [Epub ahead of print]
  21. Sun Z, Tang F, Wong R, Lok J, Szeto SKH, Chan JCK, Chan CKM, Tham CC, Ng DS, Cheung CY. Ophthalmology. 2019 Dec;126(12):1675-1684. doi: 10.1016/j.ophtha.2019.06.016. Epub 2019 Jun 26.
  22. Liao X, Jin C, Chen W, Zhang G, Cen LP, Ng DS, Chen H. Eye (Lond). 2019 Jul 18. doi: 10.1038/s41433-019-0537-5. [Epub ahead of print] No abstract available. Select item 310346945.
  23. Lai FHP, Iao TWU, Ng DSC, Young AL, Leung J, Au A, Ko STC, Chong KKL. Clin Exp Ophthalmol. 2019 Sep;47(7):918-924. doi: 10.1111/ceo.13525. Epub 2019 May 20.
  24. Rong SS, Lee BY, Kuk AK, Yu XT, Li SS, Li J, Guo Y, Yin Y, Osterbur DL, Yam JCS, Cheung CY, Chen LJ, Wong TY, Ng DS. Brelén ME, Ng DS, Cheung CY. JAMA Ophthalmol. 2019 May 1;137(5):550-551. doi: 10.1001/jamaophthalmol.2019.0291. No abstract available.
  25. Szeto SKH, Wong R, Lok J, Tang F, Sun Z, Tso T, Lam TCH, Tham CC, Ng DS, Cheung CY. Br J Ophthalmol. 2019 Sep;103(9):1327-1331. doi: 10.1136/bjophthalmol-2018-311924. Epub 2018 Oct 31.
  26. Huang H, Guan C, Ng DS, Liu X, Chen H. Curr Eye Res. 2019 Mar;44(3):324-328. doi: 10.1080/02713683.2018.1542735. Epub 2018 Nov 9.
  27. Ophthalmology. 2019 Dec;126(12):1675-1684. doi: 10.1016/j.ophtha.2019.06.016. Epub 2019 Jun 26.
  28. OCT Angiography Metrics Predict Progression of Diabetic Retinopathy and Development of Diabetic Macular Edema: A Prospective Study.
  29. Sun Z1, Tang F1, Wong R2, Lok J2, Szeto SKH2, Chan JCK2, Chan CKM2, Tham CC1, Ng DS1, Cheung CY3.