| 1963 | Faculty of Science founded, with the Departments of Mathematics (1954), Chemistry (1956), Physics (1956) and Biology (1957) coexisting in the respective Colleges as independent yet closely affiliated units |
| 1969 | The first M.Phil. programmes introduced |
| 1970 | Department of Electronic Engineering established |
| 1971 | Department of Biochemistry – a joint venture of the Faculties of Science and Medicine – established |
| 1973 | Department of Computer Science established |
| 1981 | The first Ph.D. programmes introduced |
| 1982 | Department of Statistics established |
| 1989 | First part-time programme, in Mathematics and Statistics, launched |
| 1990 | Second part-time programme, in Biology and Chemistry, launched |
| 1991 | Departments of Electronic Engineering and Computer Science left the Faculty of Science to form the new Faculty of Engineering |
| 1995-1998 | Part-time programmes phased out in view of increased provision of similar courses by other tertiary institutions, and later redeployed the resources to developing new full-time programmes |
| 1994 | Environmental Science and Food & Nutritional Sciences, first two out of seven new undergraduate interdisciplinary programmes, launched |
| 1998 | Materials Science (later renamed Materials Science and Engineering in 2001) and Molecular Biotechnology programmes launched |
| 1999 | Chinese Medicine programme launched (administered under the School of Chinese Medicine) |
| 2000 | Risk Management Science programme launched |
| 2001 | Applied Chemistry with Management Studies programme launched, which was subsequently phased out by 2007 |
| 2006 | Double Degree Programme in Mathematics and Information Engineering launched (jointly administered by the Faculties of Science and Engineering) |
| 2009 | Cell and Molecular Biology Programme launched; Interdisciplinary Major Programme in Quantitative Finance and Risk Management Science launched (jointly administered by the Faculties of Science and Business Administration) |
| 2010 | Establishment of the School of Life Sciences by merging Biochemistry and Biology departments, and four programmes, Cell and Molecular Biology, Environmental Science, Food and Nutritional Sciences and Molecular Biotechnology, under the Faculty of Science |
| 2012 | SCIENCE broad-based admission scheme and Earth System Science programme launched |
| 2013 | Science Faculty 50th Anniversary; The School of Chinese Medicine migrated to the Faculty of Medicine |
| 2014 | Natural Sciences, the first programme at the Science Faculty for articulation of local Associate Degree/Higher Diploma Holders, launched |
| 2017 | Science, Technology And Research Stream (STARS) launched |
