履歷(教育及工作經驗)

教育：

1. 1997 河南中醫藥大學醫學學士 (中醫學)
2. 2000 成都中醫藥大學醫學碩士 (中醫內科學)
3. 2003 上海中醫藥大學醫學博士 (中醫內科學)

工作經驗：

1. 2003-2005 同濟大學附屬上海市第十人民醫院中醫心腦血管病臨床醫學中心主治醫師
2. 2006-2008 香港理工大學康復治療科學系博士後研究員
3. 2008-2009 澳大利亞悉尼大學醫學科學院生理系博士後研究員
4. 2009-2010 香港理工大學康復治療科學系副研究員
5. 2011-2011 香港中文大學醫學院威爾斯親王醫院矯形外科及創傷學系副研究員
6. 2011-2017 香港中文大學中醫學院助理教授
7. 2017至今 香港中文大學中醫學院副教授
8. 2018至今 香港中文大學中醫學院助理院長

教學

1. BCME3102 中醫內科學 (一)
2. BCME3202 中醫內科學 (二)
3. BCME3208 香港醫療制度
4. BCME4107 五官科
5. BCME4200 中醫學研究方法
6. BCME5405 内科學(中醫)(一)
7. BCME5505 内科學(中醫)(二)
8. BCME6125 中醫古籍導讀
9. BCME6160 當代中醫研究方法及論文
10. BCME6506 針灸學研究方法
11. BCME6507 中醫專題講座
12. BCME6510 針灸專題研究及論文

科研範圍

分子機理發現以及基於中醫藥天然產物和基因干預策略的藥物開發研究：

1. 肌肉骨骼系統疾病（骨質疏鬆、骨折、骨壞死、老年性肌量減少症、失重性肌肉萎縮和肌肉創傷）
2. 癌症（卵巢癌、乳腺癌、骨肉瘤等）
3. 心腦血管疾病 （動脈粥樣硬化性心腦血管疾病中醫傳統理論和實驗研究）
4. 呼吸系統疾病（塵肺病）

著作及論文（選列)

1. Zhang ZK, Li J, Guan D, Liang C, Zhuo Z, Liu J, Lu A, Zhang G, Zhang BT*. A newly identified lncRNA MAR1 acts as a miR-487b sponge to promote skeletal muscle differentiation and regeneration. Journal of Cachexia, Sarcopenia and Muscle 9(3):613-626, 2018. (Impact factor: 9.697; Ranking: Q1, 8 of 155 in Medicine, General & Internal)
2. Li F, Lu J, Liu J, Liang C, Wang M, Wang L, Li D, Yao H, Zhang Q, Wen J, Zhang ZK, Li J, Lv Q, He X, Guo B, Guan D, Yu Y, Dang L, Wu X, Li Y, Chen G, Jiang F, Sun S, Zhang BT*, Lu A, Zhang G. A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer. Nature Communications 2017; 8: 1390. (Impact factor: 12.124; Ranking: Q1, 3 of 64 in Multidisciplinary Sciences)
3. Liang C, Wang L, Zhang ZK, Wang C, Li J, He B, Zhu H, Zhang BT*, Li F, Lu A, Zhang G. Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGF-A in osteosarcoma. Biomaterials 147:68-85, 2017. (Impact factor: 8.402; Ranking: Q1, 1 out of 33 in Materials Science, Biomaterials)
4. Li J, Liang C, Zhang ZK, Pan X, Peng S, Lee WS, Lu A, Lin Z, Zhang G, Leung WN, Zhang BT*. TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis. Cell Discovery 3:17023, 2017.
5. Liu J, Liang C, Guo B, Wu X, Li D, Zhang Z, Zheng K, Dang L, He X, Lu C, Peng S, Pan X, Zhang BT*, Lu A, Zhang G. Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging. Aging Cell 16(2): 360-376, 2017 (Impact factor: 6.714; Ranking: Q1, 2 of 49 in Geriatrics & Gerontology)
6. Zhang ZK, Li J, Liu J, Guo B, Leung A, Zhang G, Zhang BT*. Icaritin requires Phosphatidylinositol 3 kinase (PI3K)/Akt signaling to counteract skeletal muscle atrophy following mechanical unloading. Scientific Reports 6:20300, 2016. (Impact factor: 4.259; Ranking: Q1, 10 of 64 in Multidisciplinary Sciences)
7. Zhang ZK, Li J, Yan DX, Leung WN, Zhang BT*. Icaritin Inhibits Collagen Degradation-Related Factors and Facilitates Collagen Accumulation in Atherosclerotic Lesions: A Potential Action for Plaque Stabilization. International Journal of Molecular Sciences 17(2): E169, 2016. (Impact factor: 3.226; Ranking: Q2, 54 of 166 in Chemistry, Multidisciplinary)
8. Liang C, Guo B, Wu H, Shao N, Li D, Liu J, Dang L, Wang C, Li H, Li S, Lau WK, Cao Y, Yang Z, Lu C, He X, Au DWT, Pan X, Zhang BT, Lu C, Zhang H, Yue KM, Qian A, Shang P, Xu JK, Xiao L, Bian Z, Tan W, Liang Z, He F, Zhang L, Lu AP & Zhang G. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. Nature Medicine 21(3):288-94, 2015. (Impact factor: 29.886 ; Ranking: Q1, 2 of 290 in Biochemistry & Molecular Biology; 3 of 190 in Cell Biology; 1 of 128 in Medicine, Research & Experimental)
9. Peng S, Zhang G, Zhang BT*, Guo B, He Y, Bakker AJ, Pan X, Zhen W, Hung L, Qin L, Leung WN. The beneficial effect of Icaritin on osteoporotic bone is dependent on the treatment initiation timing in adult ovariectomized rats. Bone 55(1):230-40, 2013. (Impact factor: 4.140; Ranking: Q1, 32 of 138 in Endocrinology & Metabolism)
10. Zhang G, Guo B, Wu H, Tang T, Zhang BT*, Zheng L, He Y, Yang Z, Pan X, Chow H, To K, Li Y, Li D, Wang X, Wang Y, Lee K, Hou Z, Dong N, Li G, Leung K, Hung L, He F, Zhang L*, Qin L*. A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nature Medicine 18(2): 307-314, 2012. (# Co-first author) (Impact factor: 29.886 ; Ranking: Q1, 2 of 290 in Biochemistry & Molecular Biology; 3 of 190 in Cell Biology; 1 of 128 in Medicine, Research & Experimental)

 *Corresponding author