Prof. Matthew T.V. Chan
MB BS, FANZCA, FHKCA, FHKAM(Anaesthesiology)

Professor
Department of Anaesthesia and Intensive Care
The Chinese University of Hong Kong


Honorary Consultant
Prince of Wales Hospital
Shatin, NT Hong Kong SAR


 

Publications:

For details about citations arising from my publications and links to online versions of some of the publications, refer to:
http://www.researcherid.com/rid/J-2884-2013(Researcher ID:J-2884-2013)

 
  • Buse GL, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC, Sigamani A, Sessler DI, Berwanger O, Biccard BM, Pearse R, Urrutia G, Szczeklik RW, Garutti I, Srinathan S, Malaga G, Abraham V, Chow CK, Jacka MJ, Tiboni M, Ackland G, Macneil D, Sapsford R, Leuwer M, Le Manach Y, Devereaux PJ. Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis. Can J Surg. 2018;61(3):185-94. 
  • Chan H, Zhao S, Zhang L, Ho J, Leung CCH, Wong WT, Tian Y, Liu X, Kwong TNY, Chan RCY, Yu SSB, Wang MHT, Tse G, Wong SH, Chan MTVWu WKK. Clostridium difficile toxin B induces autophagic cell death in colonocytes. J Cell Mol Med. 2018;22(4):2469-77.
  • Chan MTV, Chow BK, Lo T, Ko FW, Ng SS, Gin T, Hui DS. Exhaled air dispersion during bag-mask ventilation and sputum suctioning - Implications for infection control. Sci Rep-Uk. 2018;8.  
  • Graham MM, Sessler DI, Parlow JL, Biccard BM, Guyatt G, Leslie K, Chan MTV, Meyhoff CS, Xavier D, Sigamani A, Kumar PA, Mrkobrada M, Cook DJ, Tandon V, Alvarez-Garcia J, Villar JC, Painter TW, Landoni G, Fleischmann E, Lamy A, Whitlock R, Le Manach Y, Aphang-Lam M, Cata JP, Gao P, Terblanche NCS, Ramana PV, Jamieson KA, Bessissow A, Mendoza GR, Ramirez S, Diemunsch PA, Yusuf S, Devereaux PJ. Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery. Ann Intern Med. 2018;168(4):237-+. 

 

  •  Kwong TNY, Wang XS, Nakatsu G, Chow TC, Tipoe T, Dai RZW, Tsoi KKK, Wong MCS, Tse G, Chan MTV, Chan FKL, Ng SC, Wu JCY, Wu WKK, Yu J, Sung JJY, Wong SH. Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer. Gastroenterology. 2018;155(2):383-+.  
  • Li XC, Xu WQ, Kang W, Wong SH, Wang MY, Zhou Y, Fang XD, Zhang XQ, Yang HM, Wong CH, To KF, Chan SL, Chan MTV, Sung JJY, Wu WKK, Yu J. Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features. Theranostics. 2018;8(6):1740-51. 
  • Li Z, Chen C, Lin YX, Li XY, Tan HN, Chan MTVWu WKK, Zhan ST, Cao Q, Shen JX. A novel probe for measuring tissue bioelectrical impedance to enhance pedicle screw placement in spinal surgery. Am J Transl Res. 2018;10(7):2205-12. 
  • Li Z, Jiang C, Li XY, Wu WKK, Chen X, Zhu SB, Ye CH, Chan MTV, Qian WW. Circulating microRNA signature of steroid-induced osteonecrosis of the femoral head. Cell Proliferat. 2018;51(1). 
  • Li Z, Li XY, Jiang C, Qian WW, Tse G, Chan MTVWu WKK. Long non-coding RNAs in rheumatoid arthritis. Cell Proliferat. 2018;51(1). 
  • Li Z, Shen JX, Chan MTVWu WKK. The long non-coding RNA SPRY4-IT1: An emerging player in tumorigenesis and osteosarcoma. Cell Proliferat. 2018;51(4). 
  • Li Z, Yang B, Weng XS, Tse G, Chan MTVWu WKK. Emerging roles of MicroRNAs in osteonecrosis of the femoral head. Cell Proliferat. 2018;51(1).
  • Lindroth H, Bratzke L, Purvis S, Brown R, Coburn M, Mrkobrada M, Chan MTV, Davis DHJ, Pandharipande P, Carlsson CM, Sanders RD. Systematic review of prediction models for delirium in the older adult inpatient. Bmj Open. 2018;8(4).  
  • Myles PS, Bellomo R, Corcoran T, Forbes A, Peyton P, Story D, Christophi C, Leslie K, McGuinness S, Parke R, Serpell J, Chan MTV, Painter T, McCluskey S, Minto G, Wallace S, Anaes ANZC, C ANZI. Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery. New Engl J Med. 2018;378(24):2263-74. 
  • Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper J, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Network ACT. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery (vol 376, pg 136, 2017). New Engl J Med. 2018;378(8):782-. 
  • Nakatsu G, Zhou HK, Wu WKK, Wong SH, Coker OO, Dai ZW, Li XC, Szeto CH, Sugimura N, Lam TYT, Yu ACS, Wang XS, Chen ZG, Wong MCS, Ng SC, Chan MTV, Chan PKS, Chan FKL, Sung JJY, Yu J. Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes. Gastroenterology. 2018;155(2):529-+. 
  • Tian Y, Liu X, Jia M, Yu H, Lichtner P, Shi Y, Meng Z, Kou S, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK, Gin TWu WKK, Chen Z, Chan MTV. Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain (vol 128, pg 587, 2018). Anesthesiology. 2018;128(5):1049-. 
  • Tian YY, Liu XD, Jia MZ, Yu H, Lichtner P, Shi YJ, Meng ZY, Kou SL, Ho IHT, Jia B, Cheng BCP, Lam CKM, Tsang S, Wong SH, Yu J, Cheng CHK, Gin TWu WKK, Chen ZY, Chan MTV, Stud PPAS. Targeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain. Anesthesiology. 2018;128(3):587-97. 
  • Tipoe TL, Wu WKK, Chung L, Gong MQ, Dong M, Liu T, Roever L, Ho J, Wong MCS, Chan MTV, Tse G, Wu JCY, Wong SH. Plasminogen Activator Inhibitor 1 for Predicting Sepsis Severity and Mortality Outcomes: A Systematic Review and Meta-Analysis. Front Immunol. 2018;9. 
  • Wang XJ, Zhang X, Chu ESH, Chen XT, Kang W, Wu F, To KF, Wong VWS, Chan HLY, Chan MTV, Sung JJY, Wu WKK, Yu J. Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis. Faseb J. 2018;32(1):37-51. 
  • Wong WT, Phua J, Joynt GM. Worldwide end-of-life practice for patients in ICUs. Curr Opin Anesthesio. 2018;31(2):172-8. 
  • Wu WKK, Sun R, Zuo T, Tian YY, Zeng ZR, Ho J, Wu JCY, Chan FKL, Chan MTV, Yu J, Sung JJY, Wong SH, Wang MH, Ng SC. A novel susceptibility locus in MST1 and gene-gene interaction network for Crohn's disease in the Chinese population. J Cell Mol Med. 2018;22(4):2368-77. 
  • Yu X, Zheng HY, Chan MTVWu WKK. Immune consequences induced by photodynamic therapy in non-melanoma skin cancers: a review. Environ Sci Pollut R. 2018;25(21):20569-74. 
  • Yu X, Zheng HY, Chan MTVWu WKK. NOVA1 acts as an oncogene in melanoma via regulating FOXO3a expression. J Cell Mol Med. 2018;22(5):2622-30. 
  • Yu X, Zheng HY, Tse G, Chan MTVWu WKK. Long non-coding RNAs in melanoma. Cell Proliferat. 2018;51(4). 
  • Zhang L, Hu W, Cho CH, Chan FKL, Yu J, Fitzgerald JR, Cheung CKY, Xiao ZG, Shen J, Li LF, Li MX, Wu JCY, Ling TKW, Chan JYK, Ko H, Tse G, Ng SC, Yu S, Wang MHT, Gin T, Ashktorab H, Smoot DT, Wong SH, Chan MTVWu WKK. Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori. J Pathol. 2018;244(4):432-44. 
  • Zhang L, Zhang YC, Wong SH, Law PTY, Zhao S, Yu J, Chan MTVWu WKK. Common Deregulation of Seven Biological Processes by MicroRNAs in Gastrointestinal Cancers. Sci Rep-Uk. 2018;8.

 

 
  • Chan MTV, Chu MHM, Lam CKM, Jia B, Tsang S, Wu WKK. Deep anesthesia: too much of a good thing? Can J Anesth. 2017;64(6):574-80.
  • Corcoran T, Kasza J, Short TG, O'Loughlin E, Chan MTV, Leslie K, Forbes A, Paech M, Myles P, Investigators E-I. Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial (EnDEX). Brit J Anaesth. 2017;118(2):190-9.
  • Ho AMH, Leung JYC, Mizubuti GB, Contardi LH, Chan MTV, Lo TSF, Lee AKT. Inattentional blindness in anesthesiology: A simulation study. J Clin Anesth. 2017;42:36-9.
  • Ho J, He WJ, Chan MTV, Tse G, Liu T, Wong SH, Leung CCH, Wong WT, Tsang S, Zhang L, Chan RYP, Gin T, Leung J, Lau BWM, Wu WKK, Ngai SPC. Eosinophilia and clinical outcome of chronic obstructive pulmonary disease: a meta-analysis. Sci Rep-Uk. 2017;7.
  • Ho J, Zhang L, Liu XD, Wong SH, Wang MHT, Lau BWM, Ngai SPC, Chan H, Choi G, Leung CCH, Wong WT, Tsang S, Gin T, Yu J, Chan MTVWu WKK. Pathological Role and Diagnostic Value of Endogenous Host Defense Peptides in Adult and Neonatal Sepsis: A Systematic Review. Shock. 2017;47(6):673-9.
  • Li Z, Li XY, Chan MTVWu WKK, Tan DX, Shen JX. Melatonin antagonizes interleukin-18-mediated inhibition on neural stem cell proliferation and differentiation. J Cell Mol Med. 2017;21(9):2163-71.
  • Li Z, Li XY, Chen C, Chan MTVWu WKK, Shen JX. Melatonin inhibits nucleus pulposus (NP) cell proliferation and extracellular matrix (ECM) remodeling via the melatonin membrane receptors mediated PI3K-Akt pathway. J Pineal Res. 2017;63(3).
  • Li Z, Shen JX, Chan MTVWu WKK. The role of microRNAs in intrahepatic cholangiocarcinoma. J Cell Mol Med. 2017;21(1):177-84.
  • Li Z, Shen JX, Chan MTVWu WKK. MicroRNA-379 suppresses osteosarcoma progression by targeting PDK1. J Cell Mol Med. 2017;21(2):315-23.
  • Liu QM, Wang QZ, Liu HG, Wu WKKChan MTV. Warning criteria for intraoperative neurophysiologic monitoring. Curr Opin Anesthesio. 2017;30(5):557-62.
  • Liu Y, Zhu ZY, Ho IHT, Shi YJ, Xie YX, Li JZ, Zhang Y, Chan MTV, Cheng CHK. Germline-specific dgcr8 knockout in zebrafish using a BACK approach. Cell Mol Life Sci. 2017;74(13):2503-11.
  • Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Network ACT. Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. New Engl J Med. 2017;376(2):136-48.
  • Peng YM, Li Y, Jian MY, Liu XY, Sun J, Jia B, Dong J, Zeng M, Lin N, Zhang L, Gelb AW, Chan MTV, Han RQ. Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke: Protocol for a randomized controlled (CANVAS) trial. Int J Stroke. 2017;12(9):991-7.
  • Wu WKK, Li XC, Wang XS, Dai RZW, Cheng ASL, Wang MHT, Kwong T, Chow TC, Yu J, Chan MTV, Wong SH. Oncogenes without a Neighboring Tumor-Suppressor Gene Are More Prone to Amplification. Mol Biol Evol. 2017;34(4):903-7.
  • Xin Y, Li Z, Zheng HY, Chan MTVWu WKK. CCAT2: A novel oncogenic long non-coding RNA in human cancers. Cell Proliferat. 2017;50(3).
  • Xin Y, Li Z, Zheng HY, Ho J, Chan MTVWu WKK. Neuro-oncological ventral antigen 1 (NOVA1): Implications in neurological diseases and cancers. Cell Proliferat. 2017;50(4).
  • Yu X, Li Z, Zheng HY, Chan MTVWu WKK. NEAT1: A novel cancer-related long non-coding RNA. Cell Proliferat. 2017;50(2).
  • Yu X, Li Z, Zheng HY, Ho J, Chan MTVWu WKK. Protective roles of melatonin in central nervous system diseases by regulation of neural stem cells. Cell Proliferat. 2017;50(2).
  • Yu X, Zheng HY, Chan MTVWu WKK. MicroRNAs: new players in cataract. Am J Transl Res. 2017;9(9):3896-903.
  • Yu X, Zheng HY, Chan MTVWu WKK. Modulation of chemoresponsiveness to platinum-based agents by microRNAs in cancer. Am J Cancer Res. 2017;7(9):1769-78.
  • Yu X, Zheng HY, Chan MTVWu WKK. BANCR: a cancer-related long non-coding RNA. Am J Cancer Res. 2017;7(9):1779-87.
  • Yu X, Zheng HY, Chan MTVWu WKK. HULC: an oncogenic long non-coding RNA in human cancer. J Cell Mol Med. 2017;21(2):410-7.