Prof. Anna Lee(???)
BPharm, Dip Hosp Clin Pharm, MPH, PhD, FACE, SFHEA

Professor and Head of Graduate Division

Department of Anaesthesia and Intensive Care
The Chinese University of Hong Kong

My current research interests are in health services research, complementary medicine, postoperative ICU delirium, patient education and systematic reviews in anaesthesia and intensive care. I am currently an editor in the Cochrane Anaesthesia, Critical and Emergency Care Group and a guest reviewer for JAMA, Annals of Internal Medicine and other top tier journals in anaesthesia, critical care medicine and public health.



Publications:

For details about citations arising from my publications and links to online versions of some of the publications, refer to:
http://www.researcherid.com/rid/B-2773-2009(Researcher ID:B-2773-2009)

 
  1. Weatherall A, Poynter E, Garner A, Lee A. Near-infrared spectroscopy monitoring in prehospital trauma patient cohort: an analysis of successful signal collection. Acta Anaesthesiol Scand 2020; 64:117-123.

 
  1. Yau DKW, Wong MKH, Wong WT, Gin T, Underwood MJ, Joynt GM, Lee A. PREhabilitation for improving QUality of recovery after ELective cardiac surgery (PREQUEL) study: protocol of a randomised controlled trial. BMJ Open 2019;9:e027974.

  2. Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Bedside tests for predicting difficult airways: an abridged Cochrane diagnostic test accuracy review. Anaesthesia 2019;74:915-928.

  3. Weatherall A, Gill M, Mulligan J, Harris C, Garner A, Lee A. Comparison of portable blood warming devices under simulated prehospital conditions: a randomised in-vitro blood circuit study. Anaesthesia 2019;74:1026-1032.

  4. Lai VKW, Li JCH, Lee A. Psychometric validation of Chinese Patient- and Family Satisfaction in the Intensive Care Unit questionnaires. J Crit Care 2019;54:58-64.

  5. Yang M, Tse AHW, Lee A, Joynt GM, Zuo Z. Large inter-individual variability in pharmacokinetics of dexmedetomidine and its two major N-glucuronides in adult intensive care unit patients. J Pharm Biomed Anal 2019;175:112777

  6. Joynt GM, Gopalan PD, Argent A, Chetty S, Wise R, Lai VKW, Hodgson E, Lee A, Joubert I, Mokgokong S, Tshukutsoane S, Richards GA, Menzes C, Mathivha LR, Espen B, Levy B, Asante K, Paruk F. The Critical Care Society of Southern Africa Consensus Statement on ICU Triage and Rationing (ConICTri). S Afr Med J 2019;109:613-29.

  7. Joynt GM, Gopalan PD, Argent A, Chetty S, Wise R, Lai VKW, Hodgson E, Lee A, Joubert I, Mokgokong S, Tshukutsoane S, Richards GA, Menzes C, Mathivha LR, Espen B, Levy B, Asante K, Paruk F. The Critical Care Society of Southern Africa Consensus Guideline on ICU Triage and Rationing (ConICTri). S Afr Med J 2019;109:630-42.

  8. Joynt GM, Gopalan PD, Argent A, Chetty S, Wise R, Lai VKW, Hodgson E, Lee A, Joubert I, Mokgokong S, Tshukutsoane S, Richards GA, Menzes C, Mathivha LR, Espen B, Levy B, Asante K, Paruk F. The Critical Care Society of Southern Africa Consensus Statement on ICU Triage and Rationing (ConICTri). S Afr J Crit Care 2019; 35: 36-52.

  9. Joynt GM, Gopalan PD, Argent A, Chetty S, Wise R, Lai VKW, Hodgson E, Lee A, Joubert I, Mokgokong S, Tshukutsoane S, Richards GA, Menzes C, Mathivha LR, Espen B, Levy B, Asante K, Paruk F. The Critical Care Society of Southern Africa Consensus Guidelines on ICU Triage and Rationing (ConICTri). S Afr J Crit Care 2019; 35: 53-65.

  10. Garner AA, Bennett N, Weatherall A, Lee A. Physician staffed helicopter emergency medical services augment ground ambulance paediatric airway management in urban areas: a retrospective cohort study. Emerg Med J 2019; 36: 678-83.

 

 
  1. Smith A, Pace N, Lee A, Herkner H. Quality of evidence in Cochrane systematic reviews in anaesthesia, critical Care and emergency Medicine. Eur J Anaesthesiol 2018; 35: 627-8.

  2. Tse AHW, Ling L, Lee A, Joynt GM. Altered pharmacokinetics in prolonged infusions of sedatives and analgesics among adult critically ill patients: a systematic review and meta-analysis. Clin Ther 2018;40:1598-1615.

  3.  Lau LLN, Li CY, Lee A, Chan SKC. The use of 5% lidocaine medicated plaster for acute postoperative pain after gynecological surgery: a pilot randomized controlled feasibility trial. Medicine (Baltimore) 2018;97:e12582.

  4. Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Airway physical examination tests for detection of difficult airway management in apparently normal patients. Cochrane Database of Systematic Reviews 2018, Issue 5, Art. No.: CD008874. DOI: 10.1002/14651858.CD008874.pub2.


  5. Lee A, Mu JL, Chiu CH, Gin T, Underwood MJ, Joynt GM. Effect of delirium subtypes in the intensive care unit on risk of fast-track failure after cardiac surgery. J Thorac Cardiovasc Surg 2018;155:268-75.e1.

  6. Joynt GM, Wong WT, Ling L, Lee A. Medical students and professionalism – do the hidden curriculum and current role models fail our future doctors? Medical Teacher 2018; 40:395-399.

 

 
  1. Tse AHW, Ling L, Joynt GM, Lee A. Prolonged infusion of sedatives and analgesics in adult intensive care patients: a systematic review of pharmacokinetic data reporting and quality of evidence. Pharmacological Research 2017;117:156-65.

  2. Lee A, Mu JL, Joynt GM, Chiu CH, Lai VKW, Gin T, Underwood MJ. Risk prediction models for delirium in the intensive care unit after cardiac surgery: a systematic review and independent external validation. Br J Anaesth 2017;118:391-9.

  3. Lee A, Cheung L, Joynt GM, Leung CCH, Wong WT, Gomersall CD. Are high nurse workload:staffing ratios associated with decreased survival in critically ill patients? A cohort study. Ann Intens Care Med 2017;7:46.


  4. Leung Y, Cheng N, Chan CP, Lee A, Wong, JK, Yan BP, Ahuja AT, Graham CA, Rainer TH. Early exclusion of major adverse cardiac events in emergency department chest pain patients: a prospective observational study. J Emerg Med 2017;53:287-294.

  5. Hounsome J, Lee A, Greenhalgh J, Lewis SR, Scholfield-Robinson O, Coldwell CH, Smith AF. A systematic review of information format and timing before schedules adult surgery for perioperative anxiety. Anaesthesia 2017;72:1265-72.

  6. Karmakar MK, Samy W, Lee A, Li JW, Chan CW, Chen PP, Tsui BCH,. Survival analysis of breast cancer patients undergoing a modified radical mastectomy with or without a thoracic paravertebral block: a 5-year follow-up of a randomized controlled trial Anticancer Res 2017;37:  5813-5820.


 
  1. Aun CST, McBride C, Lee A, Lau ASC, Chung RCK, Yeung CK, Lai KYC, Gin T. Short-term changes in postoperative cognitive function in children aged 5 to 12 years undergoing general anaesthesia: a cohort study. Medicine (Baltimore) 2016;95:e3250.

  2. Lai VKW, Lee A, Leung P, Chiu CH, Ho KM, Gomersall CD, Underwood MJ, Joynt GM. Patient and family satisfaction levels in the intensive care unit after elective cardiac surgery: study protocol for a randomized controlled trial of a preoperative patient education intervention. BMJ Open 2016; 6:e011341.

  3. Ling L, Gomersall CD, Samy W, Joynt GM, Leung CHC, Wong WT, Lee A. The effect of a freely available flipped classroom patient safety course on healthcare worker patient safety culture: a prospective controlled study. J Med Internet Res 2016;18:e180.

  4. Garner AA, Lee A, Weatherall A, Langcake M, Balogh Z. Physician staffed helicopter emergency medical service case identification – a before and after study in children. Scand J Trauma Resusc Emerg Med 2016;24:92

  5. Rainer TH, Leung YK, Lee A, Chan PY, Cheng NM, Wong JK, Yan BP, Ahuja AT, Graham CA. Add-on tests for improving risk-stratification in Emergency Department Patients with Chest Pain who are at Low to Moderate Risk of 30-day Major Adverse Cardiac Events. Int J Cardiol 2016;220:2229-306.

  6. Milligan J, Lee A, Gill M, Weatherall A, Tetlow C, Garner A. Performance comparison of improvised prehospital blood warming techniques and a commercial blood warmer. Injury 2016;47:1824-7.

  7. Lee A, Samy W, Chiu CH, Chan SKC, Gin T, Chui PT. Determinants of serum 25-hydroxyvitamin D concentrations and a screening test for moderate to severe hypovitaminosis D in Chinese Patients undergoing total joint arthroplasty. J Arthroplasty 2016;31:1921-26.


 
  1. Lee A, Chui PT, Chiu CH, Tan PE, Tam TP, Samy W, Tong PWY, Critchley LAH, Gin T.  Risk of perioperative respiratory complications and postoperative morbidity in a cohort of adults exposed to passive smoking. Ann Surg 2015;261:297-303

  2. Mu JL, Lee A, Joynt GM. Pharmacological agents for the prevention and treatment of delirium in patients undergoing cardiac surgery: systematic review and meta-analysis. Crit Care Med 2015;43:194-204.

  3. Zhu F, Gomersall CD, Ng SK, Underwood MJ, Lee A. A randomized controlled trial of Adaptive Support Ventilation mode to wean patients following fast-track cardiac valvular surgery. Anesthesiology 2015;122:832-40.

  4. Lee A, Chan SKC, Samy W, Chiu CH, Gin T. Effect of hypovitaminosis D on postoperative pain outcomes and short-term health-related quality of life after joint arthroplasty: a cohort study. Medicine 2015;94:e1812
  5. Lee A, Chan SKC, Fan LTY. Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting. Cochrane Database of Systematic Reviews 2015, Issue 11. Art. No.: CD003281. DOI: 10.1002/14651858.CD003281.pub4



  6. Lee A, Chan SKC, Fan LTY. Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting. Cochrane Database of Systematic Reviews 2015, Issue 11. Art. No.: CD003281. DOI: 10.1002/14651858.CD003281.pub4

 
  1. Ngan Kee WD, Khaw KS, Ng KF, Ng K, So R, Lee A. Synergistic interaction between fentanyl and bupivacaine given intrathecally for labor analgesia. Anesthesiology 2014;120:1126-36

  2. Karmakar MK, Samy W, Li JW, Lee A, Chan WC, Chen PP, Ho AMH. Thoracic paravertebral block and its effects on chronic pain and health-relate quality of life after modified radical mastectomy. Reg Anesth Pain Med 2014;39:289-98.

  3. Lee A, Chiu CH, Cho MWA, Gomersall CD, Lee KF, Cheung YS, Lai PBS. Factors associated with failure of enhanced recovery protocol in patients undergoing major hepatobiliary and pancreatic surgery: a retrospective cohort study. BMJ Open 2014;4:e005330.

  4. Weatherall A, Garner A, Lovell N, Redmond S, Lee A, Skowno J, Egan J. Study protocol for the PHANTOM study: prehospital assessment of noninvasive tissue oximetry monitoring. Scand J Trauma Resusc Emerg Med 2014;22:57

  5. Pace NL, Carlisle J, Eberhart LHK, Kranke P, Trivella M, Lee A , Bennett MH. Prediction models for the risk of postoperative nausea and vomiting [protocol]. Cochrane Database Systematic Review 2014, Issue 9.  CD011318.

  6. Mu J, Lee A, Joynt GM. Pharmacological agents for the prevention of delirium after cardiac surgery: a systematic review. Anaesth Intens Care 2014;42:120

  7. Mu JL, Lee A, Leung PPN, Chiu CH, Underwood MJ, Joynt GM. Comparative performance of three risk prediction models for delirium in the intensive care unit after cardiac surgery and association with fast-track failure. Intensive Care Med 2014;40(Suppl 1):S292

 

 
  1. Lee A, Chan SKC, Gin T.   "Opioid Requirements and Responses in Asians".  Culture, Brain & Analgesia Understanding and Managing Pain in Diverse Pupulations .  Ed. by Mario Incayawar, Knox Todd.   United States of America: Oxford University Press. 2013;334-348. 

  2. Ngan Kee WD, Lee A.  "Multi-Dimensional Response-Probability-Dose Curves for Bupivacaine and Ropivacaine Epidural Labour Analgesia".   Anaesthesia 2013;68 ;368-376. 

  3. Lee A, Zhu F, Underwood MJ, Gomersall CD.    "Fast-Track Failure After Cardiac Surgery: External Model Validation and Implications to ICU Bed Utilization".    Critical Care Medicine  2013;41 ;1205-1213. 

  4. Ngan Kee WD, Khaw KS, Ng F, Lee A.  "Determination and Quantification of the Interaction of Local Anaesthetics and Lipophilic Opioids Administered Intrathecally for Labour Analgesia".   International Journal of Obstetric Anesthesia  2013;22;S6. 

  5. Gin T, Lee A, Chiu CCP, Chui PT, Samy W.    "Active Smokers and Passive Exsmokers Have Increased Risks of Postoperative Morbidity After Major Elective Surgery: A Prospective Cohort Study". European Journal of Anaesthesiology 2013;30 ;236.  17AP1-9 .

  6. Lee A, Gin T, Chui PT, Tan PE, Chiu CH, TAM TP, Samy W.    "The Accuracy of Urinary Continine Immunoassay Test Strip as an Add-On Test to Self-Reported Smoking Before Major Elective Surgery".    Nicotine & Tabacco Research  2013;15 ;10;1690-1695.



  7. Nicholson A, Lewis SR, Lee A, Smith AF, Coldwell CH. Different formats and timing of educational interventions for surgical patients [protocol]. Cochrane Database Systematic Review2013, Issue 12. CD010889. 

 

 

 

 

 

 

 

 

 

 

 

 

 

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