Students

Name:Wang Qinzhou

Post: Full-time Ph.D (3-years)

Enrolled: August 2009 - July 2012

Origin: Mainland China, Shandong Province

First Degree:

Bachelor of Medicine, Binzhou Medical College, PRC

Master Degree:

Master of Clinical Medicine Science, Shandong University, PRC

Supervisor: Prof.Matthew T V Chan

Title of Thesis:

Development of GH and IGF-I Gene Therapy for Spinal Cord Injury

Outline of the Thesis:

Backgound:

Previous studies have implicated the potential benefits of the somatotropic hormones such as growth hormone (GH) and insulin-like growth factor-I (IGF-I) to improve neurologic functions after spinal cord injury. In order to apply such bench-side discovery to clinical practice, we propose a systematic study to evaluate the efficacy of such therapy.

Study Content:

Design a series of plasmid DNA constructs harboring pGH and pIGF-I.

The development of Spinal cord injury model.

Application of the above DNA constructs on the spinal cord injury model, followed by evaluation of the efficacy of the gene therapy.