Students

Name:Angel ZHU Fang

Post: Full-time Ph.D (3-years)

Enrolled: August 2010 - Present

Origin:Mainland China, Hunan Province

First Degree:

Bachelor & Master of Medicine(Seven-years), Xiangya Medical School, Central South University, Changsha, China

Supervisor:Prof. Anna LEE & Prof. Charles Gomersall

Title of Thesis:

Fast track Anasthesia in Adult Patients

Outline of the Thesis:

To contain the high cost of ICU and ensure optimal ICU utilization for patients undergoing cardiac surgery, fast-track cardiac anaesthesia (FTCA) clinical pathways have been implemented in many centres around the world. Early extubation has the potential to reduce the cost by shortening intubation time during ICU stay and overall hospital stay.

The aims of my thesis will be three folds. Firstly, I will answer the question whether the FTCA can reduce ICU length of stay without an increased risk of mortality and morbidity when compared to conventional late extubation (LE). The second challenge is how to identify the suitable candidates to include on the fast-track pathway, given the complexity and diversity of cardiac surgical procedures and differences in the level of patient comorbidities. The third part is about the protocol-driven fast-tracking patients in the ICU. I expect to develop a generalizable protocol for FTCA

Current Employment:

Postdoctoral Fellow, Department of Anesthesia and Perioperative Medicine, Western University, London, Canada.

Publications:

(A) Scientific Papers:

Lee A, Zhu F, Underwood MJ, Gomersall CD. Fast-track failure after cardiac surgery: external model validation and implications to intensive care unit bed utilization. Crit Care Med 2013; 41: 1205-13
Zhu F, Lee A, Chee YE. Fast-track cardiac care for adult cardiac surgical patients. Cochrane Database Systematic Review 2012, Issue 10. CD003587

Yang XX, Critchley LAH, Rowlands DK, Zhu F, Huang L. "Systematic Error of Cardiac Output Measured by Bolus Thermodilution With a Pulmonary Artery Catheter Compared With That Measured by an Aortic Flow Probe in a Pig Model". Journal of Cardiothoracic and Vascular Anesthesia 2013;27 ;6;1133-1139.
Zhu F, Gomersall CD, Ng SK, Underwood MJ, Lee A. A randomized controlled trial of Adaptive Support Ventilation mode to wean patients following fast-track cardiac valvular surgery. Anesthesiology 2015;122:832-40.

(B) Conference Abstracts:

Zhu F, Lee A, Chee YE. The effectiveness and safety of fast-track anaesthesia in cardiac surgery: a Cochrane systematic review update of randomized controlled trials. Eur Heart J 2012; 14 (Suppl A); A15-16

(C)Conference presentations

Zhu F, Lee A, Chee YE. The effectiveness and safety of fast-track anaesthesia in cardiac surgery: a Cochrane systematic review update of randomized controlled trials. International Congress in Cardiology, Hong Kong, 2012.
Zhu F, Lee A, Underwood M, Gomersall C. External validation and recalibration of the St Mary’s fast-track failure propensity score for adult cardiac surgical patients. 11th Congress in Evidence Based Perioperative Medicine, London, 2012.