Professor UNDERWOOD Malcolm John    
顏慕勤

Professor
MB ChB, FRCS (Ed), FRCS (CTh), MD, FCSHK, FRCP Ed

Cardiothoracic Surgery
(852) 3505 2629
mjunderwood@surgery.cuhk.edu.hk
L-6823-2016

Biography

Professor Malcolm John Underwood obtained his MB ChB from the University of Leicester in 1987 and his FRCS from the Royal College of Surgeons of Edinburgh in 1991.  This was followed by a Doctorate of Medicine in 1994 and FRCS (CTh) four years later. Professor Underwood’s scientific contributions led to him being awarded The Ronald Edwards Medal by the Society of Cardiothoracic Surgeons of Great Britain and Ireland in 1993; and The Cardiac Research Club Prize for 1992 and 1993.In 1997, he was further awarded several other prizes, most prestigious, the Francis Fontan Prize from the European Association of Cardiothoracic Surgeons for an International Clinical Fellowship in the Department of Cardiothoracic Surgery, St Luc Hospital Brussels along with a Research Fellowship from the University of Louvain (Brussels), and a travelling scholarship from the Royal College of Surgeons, Edinburgh. He has been a Consultant in Cardiothoracic Surgery for nearly 20 years and was appointed as Senior Lecturer/Consultant Cardiothoracic Surgeon at the Bristol Heart Institute in 1999. Over the years, he has held several positions of responsibility including the Programme Director for Cardiothoracic Surgery and Chairman of the Specialist Training Committee in the United Kingdom (UK) South West Region; and Research and Development Leader for the United Bristol Healthcare Trust, UK.  He was Audit Lead and subsequently Clinical Governance representative for Cardiac Surgery at the Bristol Royal Infirmary, UK. He has held his current position in Hong Kong since 2015 and his commitment to training has resulted in our Division hosting several International Fellows including those sponsored by prestigious scholarships from the Society for Cardiothoracic Surgery of Great Britain and Ireland. He is a founding member of the Aortic Asia Group which aims to support data collection and training in aortic surgery in Asia. In addition, Professor Underwood is Chairman of the Cardiothoracic Board, the College of Surgeons of Hong Kong, Lead Clinician for Quality Assurance and is Professor, Division of Cardiothoracic Surgery at the Chinese University of Hong Kong.

His clinical interests are centred on aortic surgery, valvular surgery, valve repair, in addition to clinical audit and training.

Research Interests

• Systemic responses and clinical outcomes following cardiopulmonary bypass and minimally invasive surgery
• Molecular biology of lung cancer
• Clinical outcomes and monitoring of system processes in clinical practice
• Myocardial endothelial function and protection
• Valvular surgery, repair techniques and echo follow-up
• Complex aortic surgery, neuroprotection and outcomes

Additional Information

Awards
Distinguished Surgeon Award: College of Surgeons, Singapore 2012
International Gold Medal: Royal College of Surgeons of Edinburgh 2014
Honorary Membership: Malaysian Association for Thoracic and Cardiovascular Surgery 2016
Visiting Professorship: PLA 301 Hospital, Beijing China
Honorary Fellowship: Royal College of Physicians Edinburgh 2020

Named Orations
National Hospital Grand Round, National University Hospital, Singapore: International Benchmarking and Real Time Monitoring of Clinical Outcomes: November 2010.
The Mringendra Samjhana Medical Trust Oration, XIV International Congress of Cardiac Society of Nepal and Mayo Clinic 2016 Kathmandu. Nepal: The Art of Cornering: Balancing Training, Outcomes and Beyond' November 2016.

Book Editorships
Coronary Graft Failure Ed: Associate Editor 2011 Springer ISBN: 978-973-27-2034-9
New Approaches to Aortic Diseases from Valve to Abdominal Bifurcation, Associate 2018: Springer, ISBN: 978-012-80-9979-7.
Right Heart Pathology: Associate Editor 2018: Springer, ISBN: 978-3-319-73764-5.

Selected Publications

1. Management of acute type A intramural hematoma: upfront surgery or individualized approach? A retrospective analysis and meta-analysis. Chow SCY, Wong RHL, Lakhani I, Wong MV, Tse G, Yu PSY, Ho JYK, Fujikawa T, Underwood MJ. J Thorac Dis. 2020 Mar;12(3):680-689.
2. 10-year outcomes post coronary artery bypass grafting in Asian patients with ischemic cardiomyopathy: a comprehensive analysis of survival and cardiac performance. Chow SCY, Wong RHL, Yu PSY, Ho JYK, Chan JWY, Kwok MWT, Wan S, Fujikawa T, Underwood MJ. J Thorac Dis. 2020 Mar;12(3):803-812.
3. FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer. Yang S, Liu Y, Li MY, Ng CSH, Yang SL, Wang S, Zou C, Dong Y, Du J, Long X, Liu LZ, Wan IYP, Mok T, Underwood MJ, Chen GG.Mol Cancer. 2017 Jul 17;16(1):124.
4. Functional Implication of Mitral Annular Disjunction in Mitral Valve Prolapse: A Quantitative Dynamic 3D Echocardiographic Study. Lee AP, Jin CN, Fan Y, Wong RHL, Underwood MJ, Wan S. FACC Cardiovasc Imaging. 2017 Dec;10(12):1424-1433.
5. Risk prediction models for delirium in the intensive care unit after cardiac surgery: a systematic review and independent external validation. Lee A, Mu JL, Joynt GM, Chiu CH, Lai VKW, Gin T, Underwood MJ.Br J Anaesth. 2017 Mar 1;118(3):391-399.
6. Patient and family satisfaction levels in the intensive care unit after elective cardiac surgery: study protocol for a randomised controlled trial of a preoperative patient education intervention. Lai VK, Lee A, Leung P, Chiu CH, Ho KM, Gomersall CD, Underwood MJ, Joynt GM.BMJ Open. 2016 Jun 22;6(6).
7. Cellular and molecular mechanisms of endothelial ischemia/reperfusion injury: perspectives and implications for postischemic myocardial protection. Yang Q, He GW, Underwood MJ, Yu CM.Am J Transl Res. 2016 Feb 15;8(2):765-77.