Home People Teaching Staff Alvin H. T. LEUNG

Education:

• PhD, University of Cambridge, United Kingdom, 2012
• BSc (Hons), University of Hong Kong, Hong Kong, 2008

Position:

• 2016-now, Lecturer, Department of Physics, The Chinese University of Hong Kong, Hong Kong
• 2013-2015, Postdoctoral Researcher, Biozentrum, University of Basel, Switzerland

Research Interest:

• Molecular dynamics simulations of biomolecules
• NMR spectroscopy

Honours and Awards:

• Croucher Postdoctoral Fellowship (2013)
• St John's College Benefactor Scholarship (2008)
• Sir Edward Youde Memorial Scholarship (2008)

Selected Recent Publications:

• H. T. A. Leung, O. Bignucolo, R. Aregger, S. A. Dames, A. Mazur, S. Bernèche and S. Grzesiek. A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content. J. Chem. Theory Comput. (In press)
• O. Bignucolo, H. T. A. Leung, S. Grzesiek and S. Bernèche. Backbone hydration determines the folding signature of amino acid residues. J. Am. Chem. Soc., 137 (13), pp 4300–4303 (2015)
• P. Kukic, H. T. A. Leung, F. Bemporad, F. A. Aprile, J. R. Kumita, A. De Simone, C. Camilloni and M. Vendruscolo. The structure and dynamics of the lymphocyte function associated antigen-1 I-domain in the inactive state underlie its inside-out/outside-in signalling and allosteric mechanism. Structure, 23, 1-9 (2015)
• H. T. A. Leung, P. Kukic, C. Camilloni, F. Bemporad, A. De Simone, F. A. Aprile, J. Kumita and M. Vendruscolo. NMR characterisation of the conformational fluctuations of the human lymphocyte function associated antigen-1 I domain. Protein Sci. 23 (11), 1596-606 (2014)