PHYS5610 Introduction to Biophysics
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PHYS5610 Introduction to Biophysics

Biophysics investigates biological phenomena using theoretical and experimental approaches derived from physics, such as statistical mechanics, fluid mechanics, and optics. This course provides an introduction to biophysics for students with no biology background. Students will be introduced to basic biology and physics concepts relevant to the course, followed by topics including the functions of biomolecules, physics of cellular behavior, and recent development of computer modeling and single-molecule techniques. Through this course, students will become familiar with the scope and basic approaches of biophysics research, learn how to perform computer simulations on biomolecules, and develop interest in exploring new territories of biophysics. Prerequisite: Undergraduate level thermodynamics and statistical mechanics.
Lecturer

Prof. Wang, Yi
Office: SC 208, Tel: 39436355, Email: yiwang@cuhk.edu.hk
Consultation Hour: Tue 3:00-4:30pm, SC 208 or by email/appointment

Teaching Assistant

Ms. Li Yisen
Office: SC 313, Tel:39436394 , Email:leeeasonnn@gmail.com
Consultation Hour:Tuesday 10:30-12:00 Join Zoom Meeting https://zoom.com.cn/j/410579244?pwd=RG5QckZtSVVveTAxSEJmSXZSREN4Zz09 Meeting ID: 410 579 244 Password: 5610

Lectures

  • Tue 4:30PM - 6:15PM Science center LG23
  • Thr 4:30PM - 6:15PM Science center LG23

  • Reference Books

  • Philip Nelson, Biological Physics
  • Rob Phillips, Physical Biology of the Cell
  • Meyer Jackson, Molecular and Cellular Biophysics

  • Assessment Scheme

    Homeworks 30%
    Journal presentation 15%
    Two quizzes 30%
    Final report 25%

    Course Outline

    Introduction to Biology
  • Types of cells
  • Biomolecules inside cells
    Basic concepts in biophysics
  • Friction and diffusion
  • Life in the slow lane: the low Reynolds-number world
  • Entropy, temperature and free energy
  • Chemical forces and self-assembly
    Molecules, machines and mechanisms
  • Enzymes and molecular machines
  • Membranes and machines in membranes
  • Bioelectricity and nerve impulses
    Techniques in biophysics research
  • Computer modeling and simulation
  • A brief survey of single-molecule techniques