中大職務
- 醫學院助理院長 (內地事務)
- 矯形外科及創傷學系研究生部主任
- 矯形外科及創傷學系教授
- 骨關節肌肉研究實驗室實驗室主任
- 骨質量健康評定中心主任
- 李嘉誠健康科學研究所骨科創新生物材料和藥物轉化醫學中心主任
專業範疇
- 聯合醫科、老年病學、風濕科、傳統醫學及生醫材料的臨床及科研團隊作跨學科研究,以助診斷、預防及治療骨骼損傷及骨代謝異常疾病,特別是骨質疏鬆症及骨關節炎等病症
- 骨關節影像檢查,特別是骨質密度測量、骨組織形態學定量分析法及骨生物力學指標
教育及資歷
BEd, MEd (Beijing Inst. of Phy. Ed.); PhD (German Sports Univ. Cologne); MIBMS, MSIROT, MASBMR
專注研究
- 骨關節疾病,包括骨質疏鬆、骨頭壞死及骨關節炎
- 骨骼損傷及修復,包括骨折及腱骨修復
更多資訊
獎項及榮譽
- 美國醫學暨生物工程學院院士
- 美國骨礦鹽學會會士
- 國際骨科研究聯合會會士
- 國際生物材料科學與工程學會聯合會會士
專業服務
- 國際華人骨研學會前主席
- Journal of Orthopaedic Translation主編
- Clinical Biomechanics and Chinese Journal of Orthopaedic Surgery 副編輯
- International Journal of Sports Medicine編輯委員會會員
部分論文 (只有英文版本)
- Tong WX, Zeng YL, Chow HK, Yeung W, Xu JK, Deng YJ, Chen SH, Zhao H, Zhang XL, Ho KW, QinL*, Mak KL*. Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade. Annals of the Rheumatic Diseases, 78:551-561, 2019
- Feng Q, Xu JK, Zhang KY, Yao H, Zheng NY, Zheng LZ, Wang JL, Wei KC, Xiao XF, Qin L*, Bian LM* Dynamic and cell-infiltratable hydrogels as injectable carrier of therapeutic cells and drugs for treating challenging bone defects. ACS Central Science, 5:440-450, 2019
- Huang L, Wang XL, Cao HJ, Li L, Chow HW, Tian L, Wu H, Zhang JY, Wang N, Zheng LZ, Yao XS, Yang ZJ*, Qin L*. A bone-targeting delivery system carrying osteogenic phytomolecule icaritin prevents osteoporosis in mice. Biomaterials, 182:58-72, 2018
- Wang JL, Wu YH, Li HF, Liu Y, Bai XL, Chau WH, Zheng YF*, Qin L*. Magnesium Alloy based Interference Screw Developed for ACL Reconstruction Attenuates Peri-Tunnel Bone Loss in Rabbits. Biomaterials,11;157:86-97, 2018
- Wang J, Xu J, Song B, Chow DH, Shu-Hang Yung P, Qin L*. Magnesium (Mg) based interference screws developed for promoting tendon graft incorporation in bone tunnel in rabbits. Acta Biomaterialia 63:393-410, 2017
- Zhang Y, Xu J, Ruan YC, Yu MK, O'Laughlin M, Wise H, Chen D, Tian L, Shi D, Wang J, Chen S, Feng JQ, Chow DH, Xie X, Zheng L, Huang L, Huang S, Leung K, Lu N, Zhao L, Li H, Zhao D, Guo X, Chan K, Witte F, Chan HC, Zheng Y, Qin L*. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine, 22(10):1160-1169, 2016
- Zheng LZ, Cao HJ, Chen SH, Tang T, Fu WM, Huang L, Chow DH, Wang YX, Griffith JF, He W, Zhou H, Zhao DW, Zhang G, Wang XL, Qin L*. Blockage of Src by Specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in Rabbits. J Bone Miner Res 30(11):2044-57, 2015
- Wang JL, Witte F, Xi TF, Zhang YF, Yang K, Yang YS, Zhao DW, Meng J, Li YD, Li WR, Chan KM, Qin L*. Recommendation for modifying current cytotoxicity testing standards for biodegradable magnesium-based materials. Acta Biomaterialia 21:237-49, 2015
- Qin L*, Yao D, Zheng LZ, Liu WC, Liu Z, Lei M, Huang L, Xie XH, Wang XL, Chen Y, Yao XS, Peng J, Gong H, Griffith JF, Huang YP, Zheng YP, Feng JQ, Liu Y, Chen SH, Xiao DM, Wang DP, Xiong JY, Pei DQ, Zhang P, Pan XH, Wang XH, Lee KM, CY Cheng. Phytomolecule Icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits. Biomaterials 59: 125-43, 2015
- Zhang G*, Guo BS, Wu H, Tang T, Zhang BT, Zheng LZ, He YX, Yang ZJ, Pan XH, Chow HL, To KW, Li YP, Li DH, Wang XL,Wang YX, Lee KM, Hou ZB, Dong N, Li G, Leung KS, Hung LK, He FC, Zhang LQ*, Qin L*. A delivery system targeting bone formation surface to facilitate RNAi-based bone anabolic therapy. Nature Medicine 18(2):307-14, 2012
*corresponding author